ATE446748T1 - Verwendung von r-carprofen zur vorbeugung der alzheimerschen krankheit - Google Patents

Verwendung von r-carprofen zur vorbeugung der alzheimerschen krankheit

Info

Publication number
ATE446748T1
ATE446748T1 AT05026505T AT05026505T ATE446748T1 AT E446748 T1 ATE446748 T1 AT E446748T1 AT 05026505 T AT05026505 T AT 05026505T AT 05026505 T AT05026505 T AT 05026505T AT E446748 T1 ATE446748 T1 AT E446748T1
Authority
AT
Austria
Prior art keywords
disease
carprofen
prevent alzheimer
alzheimer
nsaid
Prior art date
Application number
AT05026505T
Other languages
English (en)
Inventor
William Wechter
John Mccracken
Original Assignee
Univ Loma Linda Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/814,490 external-priority patent/US6160018A/en
Application filed by Univ Loma Linda Med filed Critical Univ Loma Linda Med
Application granted granted Critical
Publication of ATE446748T1 publication Critical patent/ATE446748T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT05026505T 1997-03-10 1998-03-04 Verwendung von r-carprofen zur vorbeugung der alzheimerschen krankheit ATE446748T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/814,490 US6160018A (en) 1995-03-13 1997-03-10 Prophylactic composition and method for alzheimer's Disease

Publications (1)

Publication Number Publication Date
ATE446748T1 true ATE446748T1 (de) 2009-11-15

Family

ID=25215202

Family Applications (2)

Application Number Title Priority Date Filing Date
AT98908904T ATE311865T1 (de) 1997-03-10 1998-03-04 Verwendung von r-enantiomeren nichtsteroidaler entzündungshemmer zur vorbeugung der alzheimerschen krankheit
AT05026505T ATE446748T1 (de) 1997-03-10 1998-03-04 Verwendung von r-carprofen zur vorbeugung der alzheimerschen krankheit

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT98908904T ATE311865T1 (de) 1997-03-10 1998-03-04 Verwendung von r-enantiomeren nichtsteroidaler entzündungshemmer zur vorbeugung der alzheimerschen krankheit

Country Status (9)

Country Link
EP (2) EP0966277B1 (de)
JP (1) JP2001514655A (de)
AT (2) ATE311865T1 (de)
AU (1) AU6682298A (de)
CA (1) CA2283255C (de)
DE (2) DE69832695T2 (de)
DK (1) DK0966277T3 (de)
ES (1) ES2253810T3 (de)
WO (1) WO1998040061A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2163986B1 (es) * 1999-07-13 2003-02-16 Menarini Lab Acidos-alfa-arilpropionicos y arilaceticos como inhibidores de la ciclooxigenasa-ii.
AU5702201A (en) * 2000-04-13 2001-10-30 Mayo Foundation Abeta<sub>42</sub> lowering agents
JP2006502188A (ja) * 2002-09-17 2006-01-19 ニューヨーク ユニバーシティ 年齢関連記憶欠陥（ａａｍｉ）、中程度認識欠陥（ｍｃｉ）、および痴呆を細胞周期インヒビターで処置する方法
EP1551384A4 (de) * 2002-10-07 2008-04-09 Encore Pharmaceuticals Inc R-nsaid-ester und ihre verwendung
US7521481B2 (en) 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
JP2007528857A (ja) * 2003-07-11 2007-10-18 ミリアド ジェネティクス， インコーポレイテッド アルツハイマー病の処置のための薬学的方法、投与レジメンおよび投薬形態
US8110681B2 (en) * 2006-03-17 2012-02-07 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Compounds for the treatment of spinal muscular atrophy and other uses
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
WO2008034244A1 (en) * 2006-09-21 2008-03-27 Waratah Pharmaceuticals Inc. The combination of a cyclohexanehexol and a nsaid for the treatment of neurodegenerative diseases
AU2007354632B2 (en) 2007-06-04 2014-06-26 Techfields Inc Pro-drugs of NSAIAs with very high skin and membranes penetration rates and their new medicinal uses
MX337730B (es) 2008-12-04 2016-03-16 Chongxi Yu Composiciones de alta penetracion y sus aplicaciones.
KR20220130239A (ko) 2012-01-18 2022-09-26 테크필즈 파마 코., 엘티디. 폐 병태의 치료를 위한 고침투 전구약물 조성물 및 그의 약제학적 조성물
JP6228302B2 (ja) 2013-07-11 2017-11-08 ユニバーシティー オブ ノース テキサス ヘルス サイエンス センター アット フォートワースＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｎｏｒｔｈ Ｔｅｘａｓ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅ Ｃｅｎｔｅｒ Ａｔ Ｆｏｒｔ Ｗｏｒｔｈ プライマリーケアセッティングにおいて神経学的疾患を検出するための血液に基づくスクリーニング
JP6364488B2 (ja) 2013-11-26 2018-07-25 ユニバーシティー オブ ノース テキサス ヘルス サイエンス センター アット フォートワースＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｎｏｒｔｈ Ｔｅｘａｓ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅ Ｃｅｎｔｅｒ Ａｔ Ｆｏｒｔ Ｗｏｒｔｈ 認知欠損を治療するための個別化医療的手法
US20220107305A1 (en) * 2018-01-18 2022-04-07 University Of North Texas Health Science Center At Fort Worth Companion Diagnostics for NSAIDS and Donepezil for Treating Specific Subpopulations of Patients Suffering from Alzheimer's Disease

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4028906A1 (de) * 1990-09-12 1992-03-19 Paz Arzneimittelentwicklung Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen
US5192753A (en) * 1991-04-23 1993-03-09 Mcgeer Patrick L Anti-rheumatoid arthritic drugs in the treatment of dementia
FR2687915B1 (fr) * 1992-02-28 1995-05-05 Rhone Poulenc Rorer Sa Composition pharmaceutique utilisable comme analgesique contenant l'acide (benzoyl-3 phenyl)-2 propionique-(r).
US5331000A (en) * 1992-03-09 1994-07-19 Sepracor Inc. Antipyretic and analgesic methods and compositions containing optically pure R(-) ketoprofen
US5382591A (en) * 1992-12-17 1995-01-17 Sepracor Inc. Antipyretic and analgesic methods using optically pure R-ketorolac
US6160018A (en) * 1995-03-13 2000-12-12 Loma Linda University Medical Center Prophylactic composition and method for alzheimer's Disease
US5955504A (en) * 1995-03-13 1999-09-21 Loma Linda University Medical Center Colorectal chemoprotective composition and method of preventing colorectal cancer
US6255347B1 (en) * 1996-06-21 2001-07-03 Advanced Research And Technology Institute Methods and compositions comprising R-ibuprofen

Also Published As

Publication number Publication date
EP0966277A1 (de) 1999-12-29
DE69841267D1 (de) 2009-12-10
DE69832695D1 (de) 2006-01-12
JP2001514655A (ja) 2001-09-11
CA2283255C (en) 2007-01-02
EP1642575A1 (de) 2006-04-05
WO1998040061A1 (en) 1998-09-17
EP0966277B1 (de) 2005-12-07
ES2253810T3 (es) 2006-06-01
AU6682298A (en) 1998-09-29
ATE311865T1 (de) 2005-12-15
CA2283255A1 (en) 1998-09-17
DE69832695T2 (de) 2006-09-14
EP1642575B1 (de) 2009-10-28
DK0966277T3 (da) 2006-03-27

Similar Documents

Publication Publication Date Title
ATE446748T1 (de) Verwendung von r-carprofen zur vorbeugung der alzheimerschen krankheit
DE50008336D1 (de) Mehrschichttablette zur verabreichung einer fixen kombination von tramadol und diclofenac
TR200000129T2 (tr) Yepyeni spiroazabisiklik heterosiklik bileşikler.
ATE369848T1 (de) Verwendung von d-serine oder d-alanine zur behandlung von schizophrenie
ID24487A (id) Senyawa-senyawa benzosikloheptatiofen
ATE174221T1 (de) Behandlung von pankreaskrankheit mit 15-keto- prostaglandin e-derivaten
DE69808440D1 (de) Verwendung von (+)mefloquine zur behandlung von malaria
IT1302243B1 (it) Sintesi dell&#39;1,1,1,3,3-pentafluoropropano.
FR2684543B1 (fr) Ligament artificiel, notamment pour la cheville.
ES2177024T3 (es) Empleo de la fanquinoma para el tratamiento de la enfermedaad de alzheimer.
ITMI913465A0 (it) Procedimento per la depurazione dell&#39;1.1.1-trifluoro-2-fuoroetano
DK0424156T3 (da) Behandling af hepatobiliær sygdom med 15-ketoprostaglandinforbindelser
DE69007065D1 (de) Verwendung von Diadenosin-5&#39;,5&#39;&#39;&#39;-p1,p4-tetraphosphat zur Herstellung eines Arzneimittels zur Behandlung von Herzkrankheiten.
DE59609977D1 (de) Trapidil zur verwendung in der therapie von immunmodulatorisch beeinflussbaren krankheitsbildern
SE9701438D0 (sv) A new process
ID20165A (id) Penggunaan asam 2-(3,4-dimetoksisinamoil)aminobenzoat untuk pembuatan obat untuk pengobatan atau pencegahan restenosis
IT1296613B1 (it) Farmaco per la cura dell&#39;ircismo contenente un adrenocorticosteroide.
DK1148129T3 (da) Modifikation af betacellulin
NO970190D0 (no) Preparat til behandling av Parkinsons sykdom
MXPA02002486A (es) Uso de dexrazoxano para tratar la psoriasis.
SE9304236D0 (sv) New use
SE9501773D0 (sv) New use
IT9047979A0 (it) Procedimento per la sintesi dell&#39;alfa-tertiofene.
IT8921468A0 (it) Composti otticamente attivi aventi attivita&#39; vasodilatatrici periferica, e loro composizioni farmaceutiche.
IT233870Y1 (it) Dispositivo simmetropredeterminatore per la riproduzione del tracciato dell&#39;arcata dentale

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties