ATE440537T1 - Vorrichtungen zum auffangen von interessierenden analyten in tränen - Google Patents

Vorrichtungen zum auffangen von interessierenden analyten in tränen

Info

Publication number
ATE440537T1
ATE440537T1 AT04719393T AT04719393T ATE440537T1 AT E440537 T1 ATE440537 T1 AT E440537T1 AT 04719393 T AT04719393 T AT 04719393T AT 04719393 T AT04719393 T AT 04719393T AT E440537 T1 ATE440537 T1 AT E440537T1
Authority
AT
Austria
Prior art keywords
interest
tears
devices
analytes
collecting analytes
Prior art date
Application number
AT04719393T
Other languages
English (en)
Inventor
Fiona Carney
Carol Morris
Yongxing Qiu
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE440537T1 publication Critical patent/ATE440537T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/42Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/41Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • A61B2010/0067Tear or lachrymal fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/43Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
AT04719393T 2003-03-12 2004-03-11 Vorrichtungen zum auffangen von interessierenden analyten in tränen ATE440537T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45415003P 2003-03-12 2003-03-12
PCT/EP2004/002543 WO2004080297A1 (en) 2003-03-12 2004-03-11 Devices for collecting analytes of interest in tears

Publications (1)

Publication Number Publication Date
ATE440537T1 true ATE440537T1 (de) 2009-09-15

Family

ID=32990873

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04719393T ATE440537T1 (de) 2003-03-12 2004-03-11 Vorrichtungen zum auffangen von interessierenden analyten in tränen

Country Status (5)

Country Link
US (2) US20040181172A1 (de)
EP (1) EP1617757B1 (de)
AT (1) ATE440537T1 (de)
DE (1) DE602004022793D1 (de)
WO (1) WO2004080297A1 (de)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR038269A1 (es) * 2002-01-09 2005-01-12 Novartis Ag Articulos polimericos que tienen un recubrimiento lubrico, y metodo para fabricarlos
US7429465B2 (en) * 2002-09-13 2008-09-30 Novartis Ag Process for analyzing tear fluid
US20040181167A1 (en) * 2003-03-13 2004-09-16 Carney Fiona Patricia Method and kits for monitoring women's health
FR2881339B1 (fr) * 2005-02-02 2009-07-10 Commissariat Energie Atomique Dispositif de prelevement moleculaire par contact
US7795359B2 (en) * 2005-03-04 2010-09-14 Novartis Ag Continuous process for production of polymeric materials
FR2903590B1 (fr) * 2006-07-13 2013-05-10 Commissariat Energie Atomique Dispositif de prelevement cellulaire par contact
US8385998B2 (en) 2008-10-24 2013-02-26 Jin Zhang Contact lens integrated with a biosensor for the detection of glucose and other components in tears
US20130204245A1 (en) * 2010-02-05 2013-08-08 Albena Ivanisevic Surface Modification of Surgical Instruments for Selective Manipulation of Biological Tissues
WO2013137496A1 (ko) * 2012-03-14 2013-09-19 엘지전자 주식회사 눈물 추출 장치
US8798332B2 (en) 2012-05-15 2014-08-05 Google Inc. Contact lenses
US9298020B1 (en) 2012-07-26 2016-03-29 Verily Life Sciences Llc Input system
US8857981B2 (en) 2012-07-26 2014-10-14 Google Inc. Facilitation of contact lenses with capacitive sensors
US9158133B1 (en) 2012-07-26 2015-10-13 Google Inc. Contact lens employing optical signals for power and/or communication
US9523865B2 (en) 2012-07-26 2016-12-20 Verily Life Sciences Llc Contact lenses with hybrid power sources
US8919953B1 (en) 2012-08-02 2014-12-30 Google Inc. Actuatable contact lenses
US9696564B1 (en) 2012-08-21 2017-07-04 Verily Life Sciences Llc Contact lens with metal portion and polymer layer having indentations
US8971978B2 (en) 2012-08-21 2015-03-03 Google Inc. Contact lens with integrated pulse oximeter
US9111473B1 (en) 2012-08-24 2015-08-18 Google Inc. Input system
US9395468B2 (en) 2012-08-27 2016-07-19 Ocular Dynamics, Llc Contact lens with a hydrophilic layer
US8820934B1 (en) 2012-09-05 2014-09-02 Google Inc. Passive surface acoustic wave communication
US20140192315A1 (en) 2012-09-07 2014-07-10 Google Inc. In-situ tear sample collection and testing using a contact lens
US9398868B1 (en) 2012-09-11 2016-07-26 Verily Life Sciences Llc Cancellation of a baseline current signal via current subtraction within a linear relaxation oscillator-based current-to-frequency converter circuit
US10010270B2 (en) 2012-09-17 2018-07-03 Verily Life Sciences Llc Sensing system
US9326710B1 (en) 2012-09-20 2016-05-03 Verily Life Sciences Llc Contact lenses having sensors with adjustable sensitivity
US8960898B1 (en) 2012-09-24 2015-02-24 Google Inc. Contact lens that restricts incoming light to the eye
US8870370B1 (en) 2012-09-24 2014-10-28 Google Inc. Contact lens that facilitates antenna communication via sensor impedance modulation
US20140088372A1 (en) 2012-09-25 2014-03-27 Google Inc. Information processing method
US8989834B2 (en) 2012-09-25 2015-03-24 Google Inc. Wearable device
US8979271B2 (en) 2012-09-25 2015-03-17 Google Inc. Facilitation of temperature compensation for contact lens sensors and temperature sensing
US8985763B1 (en) 2012-09-26 2015-03-24 Google Inc. Contact lens having an uneven embedded substrate and method of manufacture
US8821811B2 (en) 2012-09-26 2014-09-02 Google Inc. In-vitro contact lens testing
US9884180B1 (en) 2012-09-26 2018-02-06 Verily Life Sciences Llc Power transducer for a retinal implant using a contact lens
US8960899B2 (en) 2012-09-26 2015-02-24 Google Inc. Assembling thin silicon chips on a contact lens
US20140088381A1 (en) * 2012-09-26 2014-03-27 Google Inc. Facilitation of tear sample collection and testing using a contact lens
US9063351B1 (en) 2012-09-28 2015-06-23 Google Inc. Input detection system
US8965478B2 (en) 2012-10-12 2015-02-24 Google Inc. Microelectrodes in an ophthalmic electrochemical sensor
US9176332B1 (en) 2012-10-24 2015-11-03 Google Inc. Contact lens and method of manufacture to improve sensor sensitivity
US9757056B1 (en) 2012-10-26 2017-09-12 Verily Life Sciences Llc Over-molding of sensor apparatus in eye-mountable device
US8874182B2 (en) 2013-01-15 2014-10-28 Google Inc. Encapsulated electronics
US9289954B2 (en) 2013-01-17 2016-03-22 Verily Life Sciences Llc Method of ring-shaped structure placement in an eye-mountable device
US9636016B1 (en) 2013-01-25 2017-05-02 Verily Life Sciences Llc Eye-mountable devices and methods for accurately placing a flexible ring containing electronics in eye-mountable devices
US20140209481A1 (en) 2013-01-25 2014-07-31 Google Inc. Standby Biasing Of Electrochemical Sensor To Reduce Sensor Stabilization Time During Measurement
US9289623B2 (en) * 2013-03-15 2016-03-22 Johnson & Johnson Vision Care, Inc. Method and device for monitoring and treatment of seasonal affective disorder
US9161712B2 (en) 2013-03-26 2015-10-20 Google Inc. Systems and methods for encapsulating electronics in a mountable device
US9113829B2 (en) 2013-03-27 2015-08-25 Google Inc. Systems and methods for encapsulating electronics in a mountable device
US20140371560A1 (en) 2013-06-14 2014-12-18 Google Inc. Body-Mountable Devices and Methods for Embedding a Structure in a Body-Mountable Device
US9084561B2 (en) 2013-06-17 2015-07-21 Google Inc. Symmetrically arranged sensor electrodes in an ophthalmic electrochemical sensor
US9948895B1 (en) 2013-06-18 2018-04-17 Verily Life Sciences Llc Fully integrated pinhole camera for eye-mountable imaging system
US9685689B1 (en) 2013-06-27 2017-06-20 Verily Life Sciences Llc Fabrication methods for bio-compatible devices
US9814387B2 (en) 2013-06-28 2017-11-14 Verily Life Sciences, LLC Device identification
US9028772B2 (en) 2013-06-28 2015-05-12 Google Inc. Methods for forming a channel through a polymer layer using one or more photoresist layers
US9307901B1 (en) 2013-06-28 2016-04-12 Verily Life Sciences Llc Methods for leaving a channel in a polymer layer using a cross-linked polymer plug
US9492118B1 (en) 2013-06-28 2016-11-15 Life Sciences Llc Pre-treatment process for electrochemical amperometric sensor
US9636050B1 (en) 2013-11-07 2017-05-02 Verily Life Sciences Llc Methods and apparatus for forming a channel through a polymer layer using a protrusion
TWI654440B (zh) 2013-11-15 2019-03-21 美商實體科學公司 具有親水層的隱形眼鏡
US9654674B1 (en) 2013-12-20 2017-05-16 Verily Life Sciences Llc Image sensor with a plurality of light channels
US9572522B2 (en) 2013-12-20 2017-02-21 Verily Life Sciences Llc Tear fluid conductivity sensor
US9366570B1 (en) 2014-03-10 2016-06-14 Verily Life Sciences Llc Photodiode operable in photoconductive mode and photovoltaic mode
US9184698B1 (en) 2014-03-11 2015-11-10 Google Inc. Reference frequency from ambient light signal
US9789655B1 (en) 2014-03-14 2017-10-17 Verily Life Sciences Llc Methods for mold release of body-mountable devices including microelectronics
US10232531B1 (en) 2014-07-08 2019-03-19 Verily Life Sciences Llc Methods and apparatus for forming a polymer layer around a structure using a plurality of protrusions
WO2016029139A1 (en) * 2014-08-21 2016-02-25 University Of Central Florida Research Foundation, Inc. Functionalized eyewear device for detecting biomarker in tears
US9907498B2 (en) 2014-09-04 2018-03-06 Verily Life Sciences Llc Channel formation
US9459201B2 (en) 2014-09-29 2016-10-04 Zyomed Corp. Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing
AU2015360637B2 (en) 2014-12-09 2019-08-22 Tangible Science, Inc. Medical device coating with a biocompatible layer
EP3291886A1 (de) * 2015-05-04 2018-03-14 Ecole Polytechnique Federale de Lausanne (EPFL) Ophthalmische kontaktlinse mit komprimierbarer affinitätsmatrix
US10135076B1 (en) 2015-05-05 2018-11-20 Verily Life Sciences Llc Tear-activated micro-battery for use on smart contact lenses
WO2017114398A1 (en) * 2015-12-27 2017-07-06 Tsinghua-Berkeley Shenzhen Institute Compositions of diagnostic contact lenses and uses thereof
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
CA3032588C (en) * 2016-09-20 2021-03-23 Novartis Ag Hydrogel contact lenses with lubricious coating thereon
CN111936853A (zh) 2018-03-13 2020-11-13 目立康株式会社 确定系统、计算装置、确定方法及程序
EP3934623A4 (de) * 2019-03-08 2022-11-23 University of Pittsburgh - Of the Commonwealth System of Higher Education Mehrschichtige wirkstoffabgabebeschichtung für kontaktlinsen
WO2021033789A1 (en) * 2019-08-19 2021-02-25 Nexmos Co., Ltd. An aptamer-functionalized contact lens and an early diagnosis method of disease using the same
US20210338211A1 (en) * 2020-05-01 2021-11-04 TearDX LLC Ocular inserts with analyte capture and release agents

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US192657A (en) * 1877-07-03 Improvement in sand-core boxes
US45783A (en) * 1865-01-03 Improved stove
DE3218999C1 (de) * 1982-05-19 1983-12-15 Peter 8750 Aschaffenburg Höfer Vorrichtung zur Untersuchung von Tränenflüssigkeit
DE3243339C2 (de) * 1982-11-19 1986-03-27 Helmut Dr.med. 2000 Hamburg Opel Verfahren zur Gewinnung von Tränenflüssigkeit
EP0236023A3 (de) 1986-03-03 1988-09-07 Seymour Norman Blackman Nicht-eindringendes Verfahren zum Messen des Blut-Glucose-Spiegels
GB9217866D0 (en) 1992-08-21 1992-10-07 Unilever Plc Monitoring method
GB9217808D0 (en) 1992-08-21 1992-10-07 Unilever Plc Advisory method
US5352411A (en) 1993-08-13 1994-10-04 Khuri Raja N Device for determination of tear constituents
DE4335961A1 (de) * 1993-10-21 1995-04-27 Behringwerke Ag Probenabnahmebesteck zur Gewinnung von Tränenflüssigkeit
ATE182987T1 (de) 1993-11-12 1999-08-15 Unipath Ltd Nachweisverfahren und vorrichtung dafür
DK0703454T3 (da) 1994-09-23 2002-04-02 Unilever Nv Fremgangsmåder til overvågning og indretninger til anvendelse derved
GB9419267D0 (en) 1994-09-23 1994-11-09 Unilever Plc Assay devices
US6060256A (en) * 1997-12-16 2000-05-09 Kimberly-Clark Worldwide, Inc. Optical diffraction biosensor
US6451871B1 (en) * 1998-11-25 2002-09-17 Novartis Ag Methods of modifying surface characteristics
US6131580A (en) * 1998-04-17 2000-10-17 The University Of Washington Template imprinted materials by RFGD plasma deposition
US20020007113A1 (en) * 1999-08-26 2002-01-17 March Wayne Front Ocular analyte sensor
WO2001013783A1 (en) * 1999-08-26 2001-03-01 Novartis Ag Ocular analyte sensor
TW434854B (en) * 1999-11-09 2001-05-16 Advanced Semiconductor Eng Manufacturing method for stacked chip package
US20020192657A1 (en) * 2001-06-19 2002-12-19 Erwin Robert L. Bio-tolerant substrata having analyte binding microarray

Also Published As

Publication number Publication date
DE602004022793D1 (de) 2009-10-08
WO2004080297A1 (en) 2004-09-23
EP1617757A1 (de) 2006-01-25
US20080139963A1 (en) 2008-06-12
US20040181172A1 (en) 2004-09-16
EP1617757B1 (de) 2009-08-26

Similar Documents

Publication Publication Date Title
ATE440537T1 (de) Vorrichtungen zum auffangen von interessierenden analyten in tränen
ATE317242T1 (de) Vorrichtung zum sammeln von flüssigen proben
DE50310420D1 (de) Ophthalmologische Vorrichtung für die Auflösung von Augengewebe
DE60311906D1 (de) Direktes Immunosensortestverfahren
DE602004007962D1 (de) Flüssigkeitsanschluss für eine blutabnahme-vorrichtung
ATE495715T1 (de) Filtermembran mit vergrösserter oberfläche
SE0203435L (sv) Blodprovsapparat
DE10397003A5 (de) Biosensor, Biosensorchip und Biosensoreinrichtung
DE502005003997D1 (de) Ophthalmologische Vorrichtung für die Auflösung von Augengewebe
DE60225723D1 (de) Mikrobandelektrode
DE602004019406D1 (de) Sensoreinrichtung zum nachweis von sacchariden
WO2007102053A3 (en) System and method for determining human emotion by analyzing eye properties
MX2007002968A (es) Monitoreo de glucosa salivar.
DE60212522D1 (de) Vorrichtung für die Entnahme von flüssigen Proben
DE60132875D1 (de) Am Handgelenk getragene Biosignaldetektionsvorrichtung
DE60332248D1 (de) Vorrichtungen und verfahren zum nachweis von fruchtwasser in vaginalsekreten
WO2008014135A3 (en) Non-invasive analyte measurement glasses and method of use
DE602005016286D1 (de) Vorrichtung zum frühen und schnellen immunochromatographischen Nachweis von HIV und dessen Anwendung
ATE446864T1 (de) Vorrichtung zum zusammenhalten von flexiblen leitern
DE60114134D1 (de) Blutentnahmevorrichtung
DE60330632D1 (de) Vorrichtung zur Überwachung des Herzens
FR2839438B1 (fr) Sphygmographie et dispositif de mesure de la pression et du debit sanguin.
DE60327789D1 (de) Behälter für die abgabe von flüssigkeit an ein ophthalmisches chirurgisches handstück
DE50205380D1 (de) Vorrichtung zum erfassen und darstellen von bewegungen
WO2006074450A3 (en) Methods and compositions for detecting and modulating periodontal disorders and periodontal diseases

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties