ATE440103T1 - Mannose-6-phosphonat-verbindungen zur behandlung von entzündungskrankheiten - Google Patents
Mannose-6-phosphonat-verbindungen zur behandlung von entzündungskrankheitenInfo
- Publication number
- ATE440103T1 ATE440103T1 AT04752819T AT04752819T ATE440103T1 AT E440103 T1 ATE440103 T1 AT E440103T1 AT 04752819 T AT04752819 T AT 04752819T AT 04752819 T AT04752819 T AT 04752819T AT E440103 T1 ATE440103 T1 AT E440103T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- mannose
- treatment
- migration
- inflammatory diseases
- Prior art date
Links
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 3
- 230000005012 migration Effects 0.000 abstract 3
- 238000013508 migration Methods 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000001404 mediated effect Effects 0.000 abstract 2
- NBSCHQHZLSJFNQ-QTVWNMPRSA-N D-Mannose-6-phosphate Chemical compound OC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O NBSCHQHZLSJFNQ-QTVWNMPRSA-N 0.000 abstract 1
- 201000004624 Dermatitis Diseases 0.000 abstract 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 abstract 1
- 102000001696 Mannosidases Human genes 0.000 abstract 1
- 108010054377 Mannosidases Proteins 0.000 abstract 1
- HOGAGKVTOGTBKP-UHFFFAOYSA-N O=P(=O)C1CCCCO1 Chemical class O=P(=O)C1CCCCO1 HOGAGKVTOGTBKP-UHFFFAOYSA-N 0.000 abstract 1
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 abstract 1
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
- 206010046851 Uveitis Diseases 0.000 abstract 1
- 208000002552 acute disseminated encephalomyelitis Diseases 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037765 diseases and disorders Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000003278 mimic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 208000001050 sialadenitis Diseases 0.000 abstract 1
- 208000025889 stromal keratitis Diseases 0.000 abstract 1
- 206010043778 thyroiditis Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
- C07H11/04—Phosphates; Phosphites; Polyphosphates
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47171603P | 2003-05-20 | 2003-05-20 | |
| PCT/US2004/015876 WO2004104015A2 (en) | 2003-05-20 | 2004-05-20 | Mannose-6-phosphonate compounds for the treatment of inflammatory diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE440103T1 true ATE440103T1 (de) | 2009-09-15 |
Family
ID=33476877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04752819T ATE440103T1 (de) | 2003-05-20 | 2004-05-20 | Mannose-6-phosphonat-verbindungen zur behandlung von entzündungskrankheiten |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7648966B2 (de) |
| EP (1) | EP1628987B1 (de) |
| AT (1) | ATE440103T1 (de) |
| AU (1) | AU2004240938B2 (de) |
| CA (1) | CA2525328C (de) |
| DE (1) | DE602004022659D1 (de) |
| DK (1) | DK1628987T3 (de) |
| ES (1) | ES2330004T3 (de) |
| NZ (1) | NZ544085A (de) |
| PL (1) | PL1628987T3 (de) |
| PT (1) | PT1628987E (de) |
| WO (1) | WO2004104015A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2930942B1 (fr) * | 2008-05-07 | 2011-03-04 | Centre Nat Rech Scient | Nouvelles utilisations de derives de d-mannopyranose activateurs de l'angiogenese |
| EP2424542A4 (de) * | 2009-04-28 | 2012-12-19 | Pharmaxis Ltd | Phosphotetrahydropyran-verbindungen zur behandlung von wunden und fibrotischen erkrankungen |
| US20220023434A1 (en) | 2018-12-19 | 2022-01-27 | The Board Of Trustees Of The Leland Stanford Junior University | Bifunctional Molecules for Lysosomal Targeting and Related Compositions and Methods |
| JP2024524614A (ja) | 2021-07-14 | 2024-07-05 | ライシア セラピューティクス， インコーポレイテッド | Ａｓｇｐｒ細胞表面受容体結合化合物及びコンジュゲート |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0181351A4 (de) * | 1984-05-09 | 1989-06-21 | Univ Australian | Verfahren zur modulierung der immunologischen antwort. |
| US6140301A (en) * | 1995-04-27 | 2000-10-31 | The Procter & Gamble Company | Process for producing granular detergent components or compositions |
| GB9516012D0 (en) * | 1995-08-04 | 1995-10-04 | Univ Manchester | Pharmaceutical composition |
| AU728393B2 (en) | 1996-10-18 | 2001-01-11 | Australian National University, The | Novel phosphosugars and phosphosugar-containing compounds having anti-inflammatory activity |
| AUPQ872300A0 (en) | 2000-07-11 | 2000-08-03 | Praxis Pharmaceuticals Pty Ltd | Compounds and methods |
-
2004
- 2004-05-20 AT AT04752819T patent/ATE440103T1/de active
- 2004-05-20 WO PCT/US2004/015876 patent/WO2004104015A2/en not_active Ceased
- 2004-05-20 DK DK04752819T patent/DK1628987T3/da active
- 2004-05-20 AU AU2004240938A patent/AU2004240938B2/en not_active Ceased
- 2004-05-20 ES ES04752819T patent/ES2330004T3/es not_active Expired - Lifetime
- 2004-05-20 CA CA2525328A patent/CA2525328C/en not_active Expired - Fee Related
- 2004-05-20 NZ NZ544085A patent/NZ544085A/en not_active IP Right Cessation
- 2004-05-20 EP EP04752819A patent/EP1628987B1/de not_active Expired - Lifetime
- 2004-05-20 US US10/557,773 patent/US7648966B2/en not_active Expired - Fee Related
- 2004-05-20 PT PT04752819T patent/PT1628987E/pt unknown
- 2004-05-20 DE DE602004022659T patent/DE602004022659D1/de not_active Expired - Lifetime
- 2004-05-20 PL PL04752819T patent/PL1628987T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004104015A8 (en) | 2005-05-26 |
| CA2525328C (en) | 2012-07-31 |
| PT1628987E (pt) | 2009-10-29 |
| WO2004104015A2 (en) | 2004-12-02 |
| DE602004022659D1 (de) | 2009-10-01 |
| DK1628987T3 (da) | 2009-12-21 |
| WO2004104015A3 (en) | 2005-03-24 |
| US20070082850A1 (en) | 2007-04-12 |
| EP1628987A2 (de) | 2006-03-01 |
| ES2330004T3 (es) | 2009-12-03 |
| PL1628987T3 (pl) | 2010-01-29 |
| AU2004240938B2 (en) | 2009-11-19 |
| CA2525328A1 (en) | 2004-12-02 |
| US7648966B2 (en) | 2010-01-19 |
| NZ544085A (en) | 2008-10-31 |
| AU2004240938A1 (en) | 2004-12-02 |
| EP1628987B1 (de) | 2009-08-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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