ATE437890T1 - Neue multimere cd40-liganden, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von arzneimitteln - Google Patents

Neue multimere cd40-liganden, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von arzneimitteln

Info

Publication number
ATE437890T1
ATE437890T1 AT05826561T AT05826561T ATE437890T1 AT E437890 T1 ATE437890 T1 AT E437890T1 AT 05826561 T AT05826561 T AT 05826561T AT 05826561 T AT05826561 T AT 05826561T AT E437890 T1 ATE437890 T1 AT E437890T1
Authority
AT
Austria
Prior art keywords
production
residues
amino acid
multimer
ligands
Prior art date
Application number
AT05826561T
Other languages
English (en)
Inventor
Gilles Guichard
Sylvie Fournel
Olivier Chaloin
Nathalie Trouche
Sebastien Wieckowski
Johan Hoebeke
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of ATE437890T1 publication Critical patent/ATE437890T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT05826561T 2004-12-15 2005-12-15 Neue multimere cd40-liganden, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von arzneimitteln ATE437890T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0413331A FR2879202B1 (fr) 2004-12-15 2004-12-15 Nouveaux ligands multimeriques de cd40, leur procede de preparation et leur utilisation pour la preparation de medicaments
PCT/FR2005/003146 WO2006064133A2 (fr) 2004-12-15 2005-12-15 Nouveaux ligands multimeriques de cd40, leur procede de preparation et leur utilisation pour la preparation de medicaments

Publications (1)

Publication Number Publication Date
ATE437890T1 true ATE437890T1 (de) 2009-08-15

Family

ID=34953347

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05826561T ATE437890T1 (de) 2004-12-15 2005-12-15 Neue multimere cd40-liganden, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von arzneimitteln

Country Status (9)

Country Link
US (1) US8357654B2 (de)
EP (1) EP1828240B1 (de)
JP (1) JP5039561B2 (de)
AT (1) ATE437890T1 (de)
CA (1) CA2591035A1 (de)
DE (1) DE602005015754D1 (de)
ES (1) ES2331321T3 (de)
FR (1) FR2879202B1 (de)
WO (1) WO2006064133A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108976147B (zh) * 2017-05-31 2021-02-12 首都医科大学 氨基正己酰氨基甲环酰氨基正己酰碱性氨基酸，其合成，活性和应用
WO2018234455A1 (en) * 2017-06-21 2018-12-27 Xl-Protein Gmbh CONJUGATES OF PROTEIN MEDICINAL PRODUCTS AND PEPTIDES M / S
KR102389725B1 (ko) * 2020-02-14 2022-04-25 서울대학교산학협력단 피페라진산을 함유하는 사이클릭 펩티드 화합물, 이의 생산 방법, 및 이의 용도

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999052877A1 (en) * 1998-04-14 1999-10-21 Smithkline Beecham Corporation Receptor ligands
DE19963859A1 (de) 1999-12-30 2001-07-12 Apotech Res & Dev Ltd Bi- oder Oligomer eines Di-, Tri-, Quattro- oder Pentamers von rekombinanten Fusionsproteinen
GB0015426D0 (en) 2000-06-24 2000-08-16 Univ Southampton Method for generating soluble highly multimeric proteins
FR2840307B1 (fr) * 2002-05-30 2006-07-07 Centre Nat Rech Scient Nouvelles molecules multimeriques, leur procede de preparation, et leur utilisation pour la preparation de medicaments

Also Published As

Publication number Publication date
ES2331321T3 (es) 2009-12-29
US8357654B2 (en) 2013-01-22
US20100183642A1 (en) 2010-07-22
EP1828240A2 (de) 2007-09-05
JP2008524173A (ja) 2008-07-10
EP1828240B1 (de) 2009-07-29
FR2879202A1 (fr) 2006-06-16
WO2006064133A2 (fr) 2006-06-22
FR2879202B1 (fr) 2007-02-23
WO2006064133A3 (fr) 2006-08-31
JP5039561B2 (ja) 2012-10-03
CA2591035A1 (fr) 2006-06-22
DE602005015754D1 (de) 2009-09-10

Similar Documents

Publication Publication Date Title
TW458986B (en) Novel thrombin inhibitors, and the salts thereof with physiologically tolerated acids and the stereoisomers thereof
DE602007008616D1 (de) Verfahren zur herstellung von 4'-azidocytidinderivaten
DE602005020165D1 (de) Verfahren zur herstellung von l-arginin, l-ornithin oder l-citrullin
DE60230274D1 (de) Verfahren zur herstellung von l-aminosäuren durch enterobacteriaceae-stämmen mit verstärkter expression des pts-g
UA93669C2 (ru) Способ приготовления полипептидной смеси c использованием гидрогенолиза
ATE466867T1 (de) Neue topisch anwendbare wirkstoffe gegen mimische und alterabedingt falten
IL175319A (en) Phosphorus-related protein, preparations containing @ the same L @ use @ it @ and method @ to identify it
UA86037C2 (ru) Бициклические [3.1.0] производные, как ингибиторы переносчика глицина
EA200501768A1 (ru) Вич-пролекарства, способные расщепляться под действием cd26
ATE367815T1 (de) Verwendung von einem vasopressin-antagonisten wie conivaptan zur herstellung eines medikaments für die behandlung der pulmonalen hypertension
DE50308114D1 (de) Verfahren zur herstellung von 6-alkoxy-(6h)-dibenz(c,e)(1,2)-oxaphosphorinen
ATE430160T1 (de) Lipopeptid-stereoisomere, verfahren zu ihrer herstellung und nützliche zwischenprodukte
ATE437890T1 (de) Neue multimere cd40-liganden, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von arzneimitteln
WO2003102207A3 (fr) Nouvelles molecules multimeriques, leur procede de preparation, et leur utilisation pour la preparation de medicaments
ATE297428T1 (de) Modifizierte polyamide, zusammensetzungen auf basis dieser polyamide und verfahren zu ihrer herstellung
TW200502238A (en) Method for labeling phosphorylated peptides, method for selectively adsorbing phosphorylated peptides, complex compounds used in the methods, process for producing the complex compounds, and raw material compounds for the complex compounds
HUP0301396A2 (hu) Integrin inhibitor hatású peptid- és peptidutánzó konjugátumok, azokat tartalmazó implantátumok és alkalmazásuk
MXPA04005988A (es) 3,4-dihidro-1h-isoquinolin-2-il-derivados.
DE50304242D1 (de) Verfahren zur herstellung von acylphosphinoxiden
ATE272061T1 (de) Friedel-craft verfahren zur herstellung von thioxanthonen
Kende et al. A useful synthesis of the Phe-Arg phosphinic acid dipeptide isostere
DE50106464D1 (de) Verfahren zur reinigung von 2-chlor-5-chlormethylthiazol
SE9800865D0 (sv) New Process
WO2006108686A3 (en) Bnp agonists
DE60018937D1 (de) Somatostatin analoge und deren verwendung zur behandlung von krebs

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties