ATE424824T1 - Verfahren zur verhütung oder behandlung von herzarrhythmie - Google Patents

Verfahren zur verhütung oder behandlung von herzarrhythmie

Info

Publication number
ATE424824T1
ATE424824T1 AT03713563T AT03713563T ATE424824T1 AT E424824 T1 ATE424824 T1 AT E424824T1 AT 03713563 T AT03713563 T AT 03713563T AT 03713563 T AT03713563 T AT 03713563T AT E424824 T1 ATE424824 T1 AT E424824T1
Authority
AT
Austria
Prior art keywords
preventing
treating cardiac
arhythmia
cardiac arhythmia
vanoxerine
Prior art date
Application number
AT03713563T
Other languages
English (en)
Inventor
Arthur M Brown
Original Assignee
Chantest Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chantest Inc filed Critical Chantest Inc
Application granted granted Critical
Publication of ATE424824T1 publication Critical patent/ATE424824T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT03713563T 2002-02-22 2003-02-21 Verfahren zur verhütung oder behandlung von herzarrhythmie ATE424824T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/079,485 US6743797B2 (en) 2002-02-22 2002-02-22 Methods for treating cardiac arrhythmia

Publications (1)

Publication Number Publication Date
ATE424824T1 true ATE424824T1 (de) 2009-03-15

Family

ID=27752750

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03713563T ATE424824T1 (de) 2002-02-22 2003-02-21 Verfahren zur verhütung oder behandlung von herzarrhythmie

Country Status (9)

Country Link
US (5) US6743797B2 (de)
EP (2) EP2052722A1 (de)
JP (1) JP4565841B2 (de)
AT (1) ATE424824T1 (de)
AU (1) AU2003217607B2 (de)
CA (2) CA2696267A1 (de)
DE (1) DE60326548D1 (de)
NZ (1) NZ535334A (de)
WO (1) WO2003072030A2 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743797B2 (en) * 2002-02-22 2004-06-01 Chantest, Inc. Methods for treating cardiac arrhythmia
US20050054010A1 (en) * 2003-07-15 2005-03-10 Brown Arthur M. High throughput assay systems and methods for identifying agents that alter surface expression of integral membrane proteins
AU2004259199A1 (en) * 2003-07-15 2005-02-03 Chantest Corporation High throughput assay systems and methods for identifying agents that alter surface expression of integral membrane proteins
US7211407B2 (en) * 2003-07-15 2007-05-01 Chan Test, Inc. High throughput assay systems and methods for identifying agents that alter surface expression of integral membrane proteins
US20090143434A1 (en) * 2007-12-03 2009-06-04 Brown Arthur M Methods of using domperidone to terminate acute episodes of cardiac arrhythmia, to restore normal sinus rhythm or heart rate, to prevent recurrence of cardiac arrhythmia and to maintain normal sinus rhythm or heart rate in mammals
US20120010216A1 (en) * 2010-07-06 2012-01-12 Brown Arthur M Pharmaceutical compositions containing vanoxerine
US20120028992A1 (en) * 2010-08-02 2012-02-02 Brown Arthur M Pharmaceutical compositions for terminating acute episodes of cardiac arrhythmia, restoring sinus rhythm, preventing recurrence of cardiac arrhythmia and/or maintaining normal sinus rhythm in mammals
JO3192B1 (ar) * 2011-09-06 2018-03-08 Novartis Ag مركب بنزوثيازولون
US20150283131A1 (en) * 2012-10-11 2015-10-08 Chanrx Corporation Pharmaceutical compositions containing piperazine compounds in combination with a p450 inhibitor and methods of terminating acute episodes of cardiac arrhythmia, restoring normal sinus rhythm, preventing recurrence of cardiac arrhythmia and maintaining normal sinus rhythm in mammals through administration of said compositions
WO2014059338A1 (en) * 2012-10-11 2014-04-17 Chanrx Corporation Novel piperazine compounds, pharmaceutical compositions containing the same and methods of terminating acute episodes of cardiac arrhythmia, restoring normal sinus rhythm, preventing recurrence of cardiac arrhythmia and maintaining normal sinus rhythm in mammals
WO2014059367A1 (en) * 2012-10-11 2014-04-17 Chanrx Corporation Pharmaceutical compositions containing enantiomerically pure and/or racemic mixtures of chiral piperazine compounds and methods of terminating acute episodes of cardiac arrhythmia, restoring normal sinus rhythm, preventing recurrence of cardiac arrhythmia and maintaining normal sinus rhythm in mammals through administration of said compositions
WO2014176557A2 (en) * 2013-04-26 2014-10-30 Chanrx Corporation Methods for calibrating the administration of vanoxerine for terminating acute episodes of cardiac arrhythmia, restoring normal sinus rhythm, preventing recurrence of cardiac arrhythmia and maintaining normal sinus rythm in mammals
US20160304477A1 (en) * 2013-04-26 2016-10-20 Laguna Pharmaceuticals, Inc. Novel metabolites of vanoxerine compounds, pharmaceutical compositions containing the same and methods of terminating acute episodes of cardiac arrhythmia, restoring normal sinus rhythm, preventing recurrence of cardiac arrhythmia and maintaining normal sinus rhythm in mammals
US20160303114A1 (en) * 2013-04-26 2016-10-20 Laguna Pharmaceuticals, Inc. Pharmaceutical compositions containing vanoxerine and p450 inhibitors and methods of terminating acute episodes of cardiac arrhythmia, restoring normal sinus rhythm, preventing recurrence of cardiac arrhythmia and maintaining normal sinus rythym in mammals through administration of said compositions
WO2015119938A1 (en) * 2014-02-05 2015-08-13 Chanrx Corporation Pharmaceutical compositions for terminating acute episodes of cardiac arrhythmia, restoring sinus rhythm, preventing recurrence of cardiac arrhythmia, and/or maintaining normal sinus rhythm in mammals
KR101617683B1 (ko) 2015-01-09 2016-05-03 연세대학교 산학협력단 부정맥 치료제 효과 평가 시스템 및 방법
WO2019147890A1 (en) * 2018-01-26 2019-08-01 Brown Arthur M Compositions and methods for preventing the recurrence of atrial fibrillation and/or atrial flutter in a human
WO2019147889A1 (en) * 2018-01-26 2019-08-01 Brown Arthur M Compositions and methods for treating atrial fibrillation and/or atrial flutter in a human
CN111329860A (zh) * 2019-03-01 2020-06-26 杭州健石药业有限公司 Vanoxerine在持续性房颤的药中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1545094A (en) 1976-12-14 1979-05-02 Gist Brocades Nv Piperazine derivatives
NL8202636A (nl) 1982-06-29 1984-01-16 Gist Brocades Nv Piperazinederivaten, werkwijzen ter bereiding daarvan en farmaceutische preparaten die deze verbindingen bevatten.
HU196194B (en) 1986-04-28 1988-10-28 Richter Gedeon Vegyeszet Process for producing new 1-4 disubstituted piperazines and pharmaceuticals comprising the compounds
EP0485512A4 (en) 1989-08-03 1992-08-26 Us Health Slowly dissociating (tight binding) dopamine, serotonin or norepinephrine reuptake inhibitors as cocaine, amphetamine and phencyclidine antagonists
DE19547263C2 (de) * 1995-12-07 1999-04-29 Cardiotec Inc Amidinohydrazone vom Benzo[b]furan abgeleiteter Ketone, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
GB9705428D0 (en) 1997-03-15 1997-04-30 Knoll Ag Therapeutic agents
EP1077705A4 (de) * 1998-05-15 2002-04-17 Merck & Co Inc Kaliumkanalagonisten
EP1311300B1 (de) * 2000-07-14 2008-02-27 Merck & Co., Inc. Radioliganden- und bindungs-assay
EP1324780A4 (de) 2000-09-06 2005-06-22 Univ Johns Hopkins Methoden zur behandlung von herzarrhythmie
US6743797B2 (en) * 2002-02-22 2004-06-01 Chantest, Inc. Methods for treating cardiac arrhythmia

Also Published As

Publication number Publication date
JP2005524646A (ja) 2005-08-18
US20040138146A1 (en) 2004-07-15
US6743797B2 (en) 2004-06-01
NZ535334A (en) 2006-04-28
EP1485096A4 (de) 2007-07-11
US20110237604A1 (en) 2011-09-29
CA2476996A1 (en) 2003-09-04
CA2476996C (en) 2011-02-15
US8450325B2 (en) 2013-05-28
US20100069403A1 (en) 2010-03-18
US20030162793A1 (en) 2003-08-28
DE60326548D1 (de) 2009-04-23
JP4565841B2 (ja) 2010-10-20
EP2052722A1 (de) 2009-04-29
EP1485096A2 (de) 2004-12-15
EP1485096B1 (de) 2009-03-11
CA2696267A1 (en) 2003-09-04
AU2003217607B2 (en) 2008-08-14
US7700600B2 (en) 2010-04-20
US20080214554A1 (en) 2008-09-04
AU2003217607A1 (en) 2003-09-09
WO2003072030A3 (en) 2004-01-22
WO2003072030A2 (en) 2003-09-04

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Legal Events

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