ATE423139T1 - Natriumkanal-alpha-untereinheitsvarianten - Google Patents

Natriumkanal-alpha-untereinheitsvarianten

Info

Publication number
ATE423139T1
ATE423139T1 AT03767086T AT03767086T ATE423139T1 AT E423139 T1 ATE423139 T1 AT E423139T1 AT 03767086 T AT03767086 T AT 03767086T AT 03767086 T AT03767086 T AT 03767086T AT E423139 T1 ATE423139 T1 AT E423139T1
Authority
AT
Austria
Prior art keywords
variants
sodium channel
subunity
channel alpha
present
Prior art date
Application number
AT03767086T
Other languages
English (en)
Inventor
Jonathan Makielski
Bin Ye
Michael Ackerman
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Application granted granted Critical
Publication of ATE423139T1 publication Critical patent/ATE423139T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Television Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT03767086T 2002-08-02 2003-08-01 Natriumkanal-alpha-untereinheitsvarianten ATE423139T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40101802P 2002-08-02 2002-08-02

Publications (1)

Publication Number Publication Date
ATE423139T1 true ATE423139T1 (de) 2009-03-15

Family

ID=31495913

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03767086T ATE423139T1 (de) 2002-08-02 2003-08-01 Natriumkanal-alpha-untereinheitsvarianten

Country Status (7)

Country Link
US (1) US7485455B2 (de)
EP (1) EP1572094B1 (de)
JP (1) JP2006515504A (de)
AT (1) ATE423139T1 (de)
AU (1) AU2003265342A1 (de)
DE (1) DE60326267D1 (de)
WO (1) WO2004012668A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007098065A2 (en) * 2006-02-17 2007-08-30 The United States Of America As Represented By The Department Of Veterans Affairs Human sodium channel isoforms
WO2009094218A2 (en) * 2008-01-22 2009-07-30 Chromocell Corporation Novel cell lines expressing nav and methods using them
KR101857523B1 (ko) * 2016-09-22 2018-05-14 가톨릭대학교 산학협력단 Nav1.5를 안정적으로 발현하는 세포주 및 이를 이용한 약물 스크리닝 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380836A (en) * 1989-02-13 1995-01-10 Arch Development Corporation Nucleic acid encoding sodium channel protein
WO1996028537A1 (en) 1995-03-09 1996-09-19 University Of Utah Research Foundation Long qt genes and method for diagnosing or preventing the occurrence of long qt syndrome
US5599673A (en) * 1995-03-09 1997-02-04 University Of Utah Research Foundation Long QT syndrome genes
US5892018A (en) * 1996-04-02 1999-04-06 Welsh; Michael J. DNA sequences encoding a brain sodium channel protein
US6030810A (en) * 1997-02-26 2000-02-29 Delgado; Stephen Gregory Cloned tetrodotoxin-sensitive sodium channel α-subunit and a splice variant thereof
WO2002042842A2 (en) * 2000-11-22 2002-05-30 Allergan, Inc. A high-throughput screen for identifying channel blockers that selectively distinguish transient from persistent sodium channels

Also Published As

Publication number Publication date
EP1572094B1 (de) 2009-02-18
AU2003265342A1 (en) 2004-02-23
WO2004012668A3 (en) 2006-12-07
EP1572094A2 (de) 2005-09-14
AU2003265342A8 (en) 2004-02-23
EP1572094A4 (de) 2007-07-18
US20040126787A1 (en) 2004-07-01
US7485455B2 (en) 2009-02-03
DE60326267D1 (de) 2009-04-02
WO2004012668A2 (en) 2004-02-12
JP2006515504A (ja) 2006-06-01

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