ATE419232T1 - Thiolalkylbezoesäurederivate - Google Patents
ThiolalkylbezoesäurederivateInfo
- Publication number
- ATE419232T1 ATE419232T1 AT02737263T AT02737263T ATE419232T1 AT E419232 T1 ATE419232 T1 AT E419232T1 AT 02737263 T AT02737263 T AT 02737263T AT 02737263 T AT02737263 T AT 02737263T AT E419232 T1 ATE419232 T1 AT E419232T1
- Authority
- AT
- Austria
- Prior art keywords
- activity
- compounds
- thiolalkylbezoic
- acid derivatives
- effecting
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 102000003958 Glutamate Carboxypeptidase II Human genes 0.000 abstract 2
- 108090000369 Glutamate Carboxypeptidase II Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 238000009007 Diagnostic Kit Methods 0.000 abstract 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000017442 Retinal disease Diseases 0.000 abstract 1
- 208000016624 Retinal neoplasm Diseases 0.000 abstract 1
- 230000005856 abnormality Effects 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 235000010233 benzoic acid Nutrition 0.000 abstract 1
- 150000001559 benzoic acids Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 229930195712 glutamate Natural products 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 201000001119 neuropathy Diseases 0.000 abstract 1
- 230000007823 neuropathy Effects 0.000 abstract 1
- 230000036407 pain Effects 0.000 abstract 1
- 208000033808 peripheral neuropathy Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000017497 prostate disease Diseases 0.000 abstract 1
- 201000008933 retinal cancer Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29403601P | 2001-05-30 | 2001-05-30 | |
| US34274601P | 2001-12-28 | 2001-12-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE419232T1 true ATE419232T1 (de) | 2009-01-15 |
Family
ID=26968313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02737263T ATE419232T1 (de) | 2001-05-30 | 2002-05-30 | Thiolalkylbezoesäurederivate |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6740777B2 (de) |
| EP (2) | EP2025666A3 (de) |
| JP (2) | JP4292471B2 (de) |
| AT (1) | ATE419232T1 (de) |
| AU (1) | AU2002310202B2 (de) |
| CA (1) | CA2448089C (de) |
| CY (1) | CY1108893T1 (de) |
| DE (1) | DE60230624D1 (de) |
| DK (1) | DK1406867T3 (de) |
| ES (1) | ES2319509T3 (de) |
| MX (1) | MXPA03010859A (de) |
| PT (1) | PT1406867E (de) |
| WO (1) | WO2002096866A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001265111A1 (en) * | 2000-05-30 | 2001-12-11 | Guilford Pharmaceuticals Inc. | Benzenedicarboxylic acid derivatives |
| MXPA03010859A (es) * | 2001-05-30 | 2004-02-17 | Guilford Pharm Inc | Derivados de acido tioalquilbenzoico. |
| AU2002357003A1 (en) * | 2001-12-28 | 2003-07-24 | Guilford Pharmaceuticals Inc. | Indoles as naaladase inhibitors |
| AU2004217969B2 (en) * | 2003-03-03 | 2011-03-03 | Eisai Inc. | Thiolactones |
| US20040186081A1 (en) * | 2003-03-03 | 2004-09-23 | Guilford Pharmaceuticals Inc. | Naaladase inhibitors for treating opioid tolerance |
| WO2004101483A1 (ja) * | 2003-05-14 | 2004-11-25 | Riken | 新規３置換ベンゼン誘導体、その製造方法、およびそれを含む医薬組成物 |
| US8198328B2 (en) | 2004-01-21 | 2012-06-12 | New York University | Treatment of cancer using benzoic acid derivatives |
| US7282590B2 (en) * | 2004-02-12 | 2007-10-16 | The Research Foundation Of State University Of New York | Drug conjugates |
| SI2299999T1 (sl) * | 2008-06-04 | 2017-12-29 | Baylor Collega Of Medicine | Stat3 inhibitorji |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3053890A (en) * | 1960-03-31 | 1962-09-11 | California Research Corp | Reaction products of formaldehyde and o-mercaptomethylbenzoic acid |
| US4318846A (en) * | 1979-09-07 | 1982-03-09 | Syva Company | Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers |
| US5089388A (en) | 1983-04-19 | 1992-02-18 | Syntex (U.S.A.) Inc. | Antibodies for salicylate and their preparation |
| US5314918A (en) | 1987-06-24 | 1994-05-24 | Smithkline Beecham Corporation | Leukotriene antagonists |
| US5204358A (en) | 1987-11-25 | 1993-04-20 | Merck Frosst Canada, Inc. | Hetaryl styryl quinolines as leukotriene inhibitors |
| US5258551A (en) | 1991-12-18 | 1993-11-02 | Shionogi & Co., Ltd. | Process for producing α-ketoamide derivative |
| US5409780A (en) | 1992-02-13 | 1995-04-25 | Chemtrak, Inc. | Aniline analogs for hydrogen peroxide detection |
| US5316887A (en) | 1992-07-31 | 1994-05-31 | Polaroid Corporation | Thermally developable photosensitive material |
| US5453502A (en) | 1994-03-16 | 1995-09-26 | Eli Lilly And Company | 1,3,4 substituted and bicyclic derivatives of 2-azetidinones and processes for preparation thereof |
| AR006793A1 (es) | 1996-04-26 | 1999-09-29 | Ishihara Sangyo Kaisha | Compuestos pirazol o sus sales y herbicidas conteniendo los mismos |
| US6025344A (en) * | 1996-06-17 | 2000-02-15 | Guilford Pharmaceuticals Inc. | Certain dioic acid derivatives useful as NAALADase inhibitors |
| IL120531A (en) | 1997-03-26 | 2006-12-31 | Yissum Res Dev Co | Nitric oxide donors and pharmaceutical compositions containing them |
| TR200100025T2 (tr) | 1998-07-06 | 2001-12-21 | Guilford Pharmaceuticals Inc. | Farmasötik bileşikler ve kompozisyonlar olarak faydalı naaladaz inhibitörleri. |
| US6265609B1 (en) | 1998-07-06 | 2001-07-24 | Guilford Pharmaceuticals Inc. | Thio-substituted pentanedioic acid derivatives |
| CA2367787C (en) * | 1999-04-28 | 2011-07-26 | Alan P. Kozikowski | Ligands for metabotropic glutamate receptors |
| AU2001265111A1 (en) | 2000-05-30 | 2001-12-11 | Guilford Pharmaceuticals Inc. | Benzenedicarboxylic acid derivatives |
| AU2001265119A1 (en) | 2000-05-30 | 2001-12-11 | Guilford Pharmaceuticals Inc. | Naaladase inhibitors for treating amyotrophic lateral sclerosis |
| JP2003535098A (ja) * | 2000-05-30 | 2003-11-25 | ギルフォード ファーマシューティカルズ インコーポレーティッド | 網膜疾患および緑内障を治療するためのｎａａｌａｄアーゼ阻害剤 |
| MXPA03010859A (es) * | 2001-05-30 | 2004-02-17 | Guilford Pharm Inc | Derivados de acido tioalquilbenzoico. |
-
2002
- 2002-05-30 MX MXPA03010859A patent/MXPA03010859A/es active IP Right Grant
- 2002-05-30 AU AU2002310202A patent/AU2002310202B2/en not_active Expired
- 2002-05-30 PT PT02737263T patent/PT1406867E/pt unknown
- 2002-05-30 AT AT02737263T patent/ATE419232T1/de active
- 2002-05-30 JP JP2003500046A patent/JP4292471B2/ja not_active Expired - Lifetime
- 2002-05-30 EP EP08019550A patent/EP2025666A3/de not_active Withdrawn
- 2002-05-30 EP EP02737263A patent/EP1406867B1/de not_active Expired - Lifetime
- 2002-05-30 DK DK02737263T patent/DK1406867T3/da active
- 2002-05-30 WO PCT/US2002/016971 patent/WO2002096866A2/en not_active Ceased
- 2002-05-30 DE DE60230624T patent/DE60230624D1/de not_active Expired - Lifetime
- 2002-05-30 US US10/156,880 patent/US6740777B2/en not_active Expired - Lifetime
- 2002-05-30 ES ES02737263T patent/ES2319509T3/es not_active Expired - Lifetime
- 2002-05-30 CA CA2448089A patent/CA2448089C/en not_active Expired - Lifetime
-
2004
- 2004-04-07 US US10/819,146 patent/US7138543B2/en not_active Expired - Lifetime
-
2009
- 2009-01-22 JP JP2009011782A patent/JP2009149657A/ja active Pending
- 2009-03-20 CY CY20091100316T patent/CY1108893T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1406867A2 (de) | 2004-04-14 |
| JP2009149657A (ja) | 2009-07-09 |
| CA2448089C (en) | 2010-10-19 |
| WO2002096866A3 (en) | 2004-01-15 |
| AU2002310202B2 (en) | 2008-05-15 |
| JP4292471B2 (ja) | 2009-07-08 |
| DK1406867T3 (da) | 2009-04-06 |
| DE60230624D1 (en) | 2009-02-12 |
| CY1108893T1 (el) | 2014-07-02 |
| US20030100607A1 (en) | 2003-05-29 |
| MXPA03010859A (es) | 2004-02-17 |
| JP2005503353A (ja) | 2005-02-03 |
| EP2025666A3 (de) | 2010-03-31 |
| EP2025666A2 (de) | 2009-02-18 |
| CA2448089A1 (en) | 2002-12-05 |
| WO2002096866A2 (en) | 2002-12-05 |
| US6740777B2 (en) | 2004-05-25 |
| US7138543B2 (en) | 2006-11-21 |
| EP1406867B1 (de) | 2008-12-31 |
| US20040198824A1 (en) | 2004-10-07 |
| ES2319509T3 (es) | 2009-05-08 |
| PT1406867E (pt) | 2009-02-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1108893T1 (el) | Παραγωγα θειοαλκυλ βενζοϊκου οξεος | |
| WO2001092273A3 (en) | Benzenedicarboxylic acid derivatives | |
| WO2003057670A3 (en) | Indoles as naaladase inhibitors | |
| WO2002057222A3 (en) | Thiol-based naaladase inhibitors | |
| ATE440087T1 (de) | 2,4-diaminopyrimidinderivate, die sich als inhibitoren von pkc-theta eignen | |
| ATE501722T1 (de) | Therapeutische behandlung androgenrezeptorbedingter leiden | |
| NO20012765L (no) | Karboksylsyrer og karboksylsyreisosterer av N-heterosykliske forbindelser | |
| ATE380029T1 (de) | Prodrugs von gaba-analoga, zusammensetzungen und ihre verwendungszwecke | |
| DE69940951D1 (de) | Nd wachstumshemmende mittel | |
| MXPA03010328A (es) | Acidos hidroxinamicos y acil hidroxaminasas como inhibidores de naaladasa. | |
| DE60219614D1 (de) | 3, 7 thiaprostansäurederivate als mittel zur verminderung des augeninnendruckes | |
| CA2337797A1 (en) | Naaladase inhibitors useful as pharmaceutical compounds and compositions | |
| PT1562954E (pt) | Antagonistas de ccr1 para o tratamento da doenca desmielinzante inflamatoria i.a. | |
| WO2001034596A3 (en) | Pyrrolecarbonylimino derivatives as naaladase inhibitors | |
| WO2004063340A3 (en) | Methods and compositions for treating cardiovascular disease using 1722, 10280, 59917, 85553, 10653, 9235, 21668, 17794, 2210, 6169, 10102, 21061,17662,1468,12282, 6350, 9035,1820, 23652, 7301, 8925, 8701, 3533, 9462, 9123,12788,17729, 65552,1261, 21476, 33770, 9380, 2569654, 33556, 53656, 44143, 32612, 10671, 261, 44570, 4 | |
| CY1109356T1 (el) | Θειολακτονες ως αναστολεις της νααladασης | |
| ATE285773T1 (de) | Pharmazeutische zusammensetzungen zur behandlung von neurologischen krankheiten | |
| WO2002074756A3 (de) | Urokinase-inhibitoren | |
| WO2003050504A3 (en) | Methods and compositions to treat cardiovascular disease usin g 1419, 58765 and 2201 | |
| EP1958939A3 (de) | Pyrazolaminverbindungen zur Behandlung neurodegenerativer Erkrankungen | |
| ATE409469T1 (de) | Verwendung von 2,2,3,3, tetramethylcyclopropane carbonsäure derivaten zur behandlung von psychiatrischen störungen | |
| EP3982945B1 (de) | Verwendung von marimastat zur vorbeugung und/oder behandlung von epileptogenese | |
| BR0317377A (pt) | Derivados de 5-aminofenantridina como antagonistas de npy-5 | |
| WO2003039341A3 (en) | Methods and compositions to treat cardiovascular disease using 139, 258, 1261, 1486, 2398, 2414, 7660, 8587, 10183, 10550, 12680, 17921, 32248, 60489 or 93804 | |
| CN121159454A (zh) | 一种酪氨酸酶抑制剂及其制备方法与应用 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1406867 Country of ref document: EP |
|
| EEIH | Change in the person of patent owner |