ATE41742T1 - Verfahren zur herstellung von gereinigten bakteriellen antigenischen kapselpolysacchariden, die erhaltenen produkte und ihre verwendung. - Google Patents
Verfahren zur herstellung von gereinigten bakteriellen antigenischen kapselpolysacchariden, die erhaltenen produkte und ihre verwendung.Info
- Publication number
- ATE41742T1 ATE41742T1 AT82107154T AT82107154T ATE41742T1 AT E41742 T1 ATE41742 T1 AT E41742T1 AT 82107154 T AT82107154 T AT 82107154T AT 82107154 T AT82107154 T AT 82107154T AT E41742 T1 ATE41742 T1 AT E41742T1
- Authority
- AT
- Austria
- Prior art keywords
- polysaccharids
- capsule
- processes
- production
- purified bacterial
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE0/205681A BE889979A (fr) | 1981-08-14 | 1981-08-14 | Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation |
EP82107154A EP0072513B1 (de) | 1981-08-14 | 1982-08-07 | Verfahren zur Herstellung von gereinigten Bakteriellen antigenischen Kapselpolysacchariden, die erhaltenen Produkte und ihre Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE41742T1 true ATE41742T1 (de) | 1989-04-15 |
Family
ID=3843449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT82107154T ATE41742T1 (de) | 1981-08-14 | 1982-08-07 | Verfahren zur herstellung von gereinigten bakteriellen antigenischen kapselpolysacchariden, die erhaltenen produkte und ihre verwendung. |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0072513B1 (de) |
AT (1) | ATE41742T1 (de) |
BE (1) | BE889979A (de) |
DE (1) | DE3279579D1 (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0145359B1 (de) * | 1983-11-21 | 1991-01-16 | The Wellcome Foundation Limited | Komplexe, Verfahren zu ihrer Herstellung und dieselben enthaltende Formulierungen |
US4686102A (en) * | 1984-04-12 | 1987-08-11 | American Cyanamid Company | Multivalent pneumococcal vaccine and preparation thereof |
US4877613A (en) * | 1987-08-05 | 1989-10-31 | Biotech Connections, Inc. | Process for preparing veterinary acellular vaccines against gram-negative nonenteric pathogenic bacilli |
DE69012682T2 (de) * | 1989-06-12 | 1995-04-06 | Merck & Co Inc | Verfahren zur Entfernung von bakteriellen Endotoxinen aus gram-negativen Polysacchariden. |
US5714354A (en) * | 1995-06-06 | 1998-02-03 | American Home Products Corporation | Alcohol-free pneumococcal polysaccharide purification process |
ATE280834T1 (de) * | 1996-02-14 | 2004-11-15 | Merck & Co Inc | Verfahren zur präzipitation von polysacchariden |
US6410025B1 (en) | 1996-02-14 | 2002-06-25 | Merck & Co., Inc. | Polysaccharide precipitation process |
TR200102739T2 (tr) | 1999-03-19 | 2001-12-21 | Smithkline Beecham Biologicals S.A. | Aşı |
GB9909077D0 (en) | 1999-04-20 | 1999-06-16 | Smithkline Beecham Biolog | Novel compositions |
GB0022742D0 (en) | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
GB0408978D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Meningococcal fermentation for preparing conjugate vaccines |
EP1866342B1 (de) * | 2005-04-08 | 2018-11-21 | Wyeth LLC | Abtrennung von kontaminanten aus streptococcus-pneumoniae-polysaccharid durch ph-beeinflussung |
ATE548051T1 (de) | 2005-04-08 | 2012-03-15 | Wyeth Llc | Multivalente pneumokokken- polysaccharidproteinkonjugatzusammensetzung |
GB0522303D0 (en) | 2005-11-01 | 2005-12-07 | Chiron Srl | Culture method |
DK1973564T3 (da) | 2005-12-22 | 2017-01-16 | Glaxosmithkline Biologicals Sa | Vaccine omfattende streptococcus pneumoniae-kapselpolysaccharidkonjugat |
GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
WO2008104811A1 (en) * | 2007-02-28 | 2008-09-04 | Lipoxen Technologies Limited | Reduction of endotoxin in polysialic acids |
EP2155244B1 (de) * | 2007-04-23 | 2017-03-22 | Serum Institute of India Private Limited | Antigene polysaccharide und verfahren zu ihrer herstellung |
EA201391788A1 (ru) | 2007-06-26 | 2014-08-29 | Глаксосмитклайн Байолоджикалс С.А. | Вакцина, содержащая конъюгаты капсульных полисахаридов streptococcus pneumoniae |
GB0818453D0 (en) | 2008-10-08 | 2008-11-12 | Novartis Ag | Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom |
CN102099379B (zh) * | 2008-06-19 | 2013-12-11 | 本德尔分析控股有限公司 | 用于从生物聚合物材料中去除杂质的方法 |
ES2666698T3 (es) | 2008-12-18 | 2018-05-07 | Wyeth Llc | Procedimiento de control del peso molecular del polisacárido del serotipo 19A de Streptococcus pneumoniae |
HUE046859T2 (hu) | 2008-12-18 | 2020-03-30 | Wyeth Llc | Eljárás Streptococcus pneumoniae poliszacharid molekulatömegének szabályozására szén alkalmazásával |
CN106460062A (zh) | 2014-05-05 | 2017-02-22 | 美敦力公司 | 用于scd、crt、crt‑d或sca治疗识别和/或选择的方法和组合物 |
EP3034516A1 (de) | 2014-12-19 | 2016-06-22 | Novartis AG | Reinigung von Streptokokkenkapselpolysaccharid |
US11191822B2 (en) | 2016-06-22 | 2021-12-07 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Pneumococcal polysaccharide-protein conjugate composition |
EP3269385A1 (de) | 2016-07-12 | 2018-01-17 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Pneumokokken-polysaccharid-proteinkonjugatzusammensetzung |
EP3551668A1 (de) | 2016-12-06 | 2019-10-16 | GlaxoSmithKline Biologicals S.A. | Reinigungsverfahren für kaspelpolysaccharid |
EP3900739A1 (de) | 2020-04-21 | 2021-10-27 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Synthetische streptococcus-pneumoniae-saccharid-konjugate zum konservierten membranprotein |
EP3919076A1 (de) | 2020-06-02 | 2021-12-08 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Synthetische oligosaccharidimpfstoffe gegen streptococcus pneumoniae mit mikropartikel-adjuvans-formulierungen |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3636192A (en) * | 1970-01-13 | 1972-01-18 | Us Army | Meningococcal polysaccharide vaccines |
US3978209A (en) * | 1975-03-24 | 1976-08-31 | Merck & Co., Inc. | Endotoxin free meningococcus polysaccharides |
FR2388563A1 (fr) * | 1977-04-29 | 1978-11-24 | Fabre Sa Pierre | Vaccins acellulaires perfectionnes contenant des polysaccharides capsulaires |
US4123520A (en) * | 1977-08-01 | 1978-10-31 | Merck & Co., Inc. | Method for preparing high molecular weight meningococcal Group C vaccine |
US4134214A (en) * | 1977-08-05 | 1979-01-16 | Merck & Co., Inc. | Freeze-drying process for the preparation of meningococcus vaccine without degradation of potency |
DE2748132A1 (de) * | 1977-10-27 | 1979-05-03 | Behringwerke Ag | Stabilisator fuer polysaccharid |
NZ188211A (en) * | 1977-10-28 | 1984-09-28 | American Cyanamid Co | Isolation of polyribosyl ribitol phosphate(prp)from haemophilus influenzae type b;vaccine comprising prp and bordetellapertussis antigens |
CA1115210A (en) * | 1977-11-28 | 1981-12-29 | Dennis J. Carlo | Pneumococcal vaccine |
US4235994A (en) * | 1978-06-26 | 1980-11-25 | Merck & Co., Inc. | High molecular weight meningococcal group C vaccine and method for preparation thereof |
US4264764A (en) * | 1979-01-12 | 1981-04-28 | Merck & Co., Inc. | Meningitis vaccine |
US4221906A (en) * | 1979-03-19 | 1980-09-09 | American Cyanamid Company | Stabilization of pneumococcal polysaccharides |
US4242501A (en) * | 1979-08-08 | 1980-12-30 | American Cyanamid Company | Purification of pneumococcal capsular polysaccharides |
PT72812B (en) * | 1980-04-14 | 1983-02-16 | Merck & Co Inc | Process for preparing group b streptococcal capsular polysccha-rides |
US4407949A (en) * | 1980-09-22 | 1983-10-04 | Merck & Co., Inc. | Meningitis vaccine |
-
1981
- 1981-08-14 BE BE0/205681A patent/BE889979A/fr not_active IP Right Cessation
-
1982
- 1982-08-07 EP EP82107154A patent/EP0072513B1/de not_active Expired
- 1982-08-07 DE DE8282107154T patent/DE3279579D1/de not_active Expired
- 1982-08-07 AT AT82107154T patent/ATE41742T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0072513A2 (de) | 1983-02-23 |
EP0072513A3 (en) | 1986-02-19 |
DE3279579D1 (en) | 1989-05-03 |
EP0072513B1 (de) | 1989-03-29 |
BE889979A (fr) | 1982-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |