ATE407146T1 - Ein neues chimäres protein für die prävention und die behandlung einer hiv infektion - Google Patents
Ein neues chimäres protein für die prävention und die behandlung einer hiv infektionInfo
- Publication number
- ATE407146T1 ATE407146T1 AT00918015T AT00918015T ATE407146T1 AT E407146 T1 ATE407146 T1 AT E407146T1 AT 00918015 T AT00918015 T AT 00918015T AT 00918015 T AT00918015 T AT 00918015T AT E407146 T1 ATE407146 T1 AT E407146T1
- Authority
- AT
- Austria
- Prior art keywords
- prevention
- treatment
- proteins
- hiv infection
- chimeric protein
- Prior art date
Links
- 108020001507 fusion proteins Proteins 0.000 title abstract 3
- 102000037865 fusion proteins Human genes 0.000 title abstract 3
- 208000031886 HIV Infections Diseases 0.000 title 1
- 208000037357 HIV infectious disease Diseases 0.000 title 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108010043277 recombinant soluble CD4 Proteins 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- AIDS & HIV (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12468199P | 1999-03-16 | 1999-03-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE407146T1 true ATE407146T1 (de) | 2008-09-15 |
Family
ID=22416252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00918015T ATE407146T1 (de) | 1999-03-16 | 2000-03-16 | Ein neues chimäres protein für die prävention und die behandlung einer hiv infektion |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1161455B1 (de) |
| JP (1) | JP2002538814A (de) |
| AT (1) | ATE407146T1 (de) |
| AU (1) | AU765218B2 (de) |
| CA (1) | CA2361292C (de) |
| DE (1) | DE60040136D1 (de) |
| ES (1) | ES2313886T3 (de) |
| WO (1) | WO2000055207A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9925966D0 (en) | 1999-11-02 | 1999-12-29 | Petrik Juraj | Threapeutic vaccines against variable viruses and other targets |
| IL141023A0 (en) * | 2001-01-22 | 2002-02-10 | Gavish Galilee Bio Appl Ltd | Recombinant polypeptides for effective hiv neutralization |
| CA2444854A1 (en) * | 2001-04-26 | 2002-11-07 | Avidia Research Institute | Combinatorial libraries of monomer domains |
| AU2002337885B1 (en) | 2001-10-16 | 2003-04-28 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Broadly cross-reactive neutralizing antibodies against human ummunodeficiency virus selected by Env-CD4-co-receptor complexes |
| WO2003040311A2 (en) | 2001-10-25 | 2003-05-15 | The Government Of The United States Of America As Represented By The Secretary Of Health And Human Services | Efficient inhibition of hiv-1 viral entry through a novel fusion protein including of cd4 |
| WO2003095492A1 (en) * | 2002-05-06 | 2003-11-20 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Identification of novel broadly cross-reactive hiv-1 neutralizing human monoclonal antibodies |
| CA2484930A1 (en) | 2002-05-06 | 2003-11-13 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Identification of novel broadly cross-reactive neutralizing human monoclonal antibodies using sequential antigen panning of phage display libraries |
| MX351062B (es) * | 2003-05-16 | 2017-09-29 | Acorda Therapeutics Inc | Proteinas de fusion para el tratamiento del snc. |
| ES2319838B1 (es) * | 2006-09-29 | 2010-02-11 | Consejo Superior Investig. Cientificas | Uso de inhibidores de la actividad de la proteina filamina a, para la elaboracion de composiciones farmaceuticas, compuestos inhibidores de dicha actividad, composiciones farmaceuticas y sus aplicaciones terapeuticas y procedimiento identificacion de dichos compuestos inhibidores. |
| WO2010070394A1 (en) * | 2008-12-17 | 2010-06-24 | Universite Pierre Et Marie Curie-Paris Vi | Modulators of the cx3cr1 receptor and therapeutic uses thereof |
| EP3660035A1 (de) * | 2015-05-30 | 2020-06-03 | Molecular Templates, Inc. | Deimmunisierte shigatoxin-a-untereinheitsgerüste und zellgerichtete moleküle damit |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0956044A4 (de) * | 1996-06-14 | 2005-01-05 | Progenics Pharm Inc | Verwendungen eines chemokin-rezeptors zur inhibierung einer hiv-1 infektion |
| US6432699B1 (en) * | 1997-03-28 | 2002-08-13 | New York University | Viral vectors having chimeric envelope proteins containing the IgG-binding domain of protein A |
-
2000
- 2000-03-16 AT AT00918015T patent/ATE407146T1/de not_active IP Right Cessation
- 2000-03-16 EP EP00918015A patent/EP1161455B1/de not_active Expired - Lifetime
- 2000-03-16 CA CA2361292A patent/CA2361292C/en not_active Expired - Fee Related
- 2000-03-16 DE DE60040136T patent/DE60040136D1/de not_active Expired - Lifetime
- 2000-03-16 AU AU38896/00A patent/AU765218B2/en not_active Ceased
- 2000-03-16 ES ES00918015T patent/ES2313886T3/es not_active Expired - Lifetime
- 2000-03-16 JP JP2000605633A patent/JP2002538814A/ja not_active Ceased
- 2000-03-16 WO PCT/US2000/006946 patent/WO2000055207A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ES2313886T3 (es) | 2009-03-16 |
| CA2361292A1 (en) | 2000-09-21 |
| DE60040136D1 (de) | 2008-10-16 |
| AU765218B2 (en) | 2003-09-11 |
| EP1161455A1 (de) | 2001-12-12 |
| WO2000055207A1 (en) | 2000-09-21 |
| AU3889600A (en) | 2000-10-04 |
| EP1161455B1 (de) | 2008-09-03 |
| CA2361292C (en) | 2012-05-29 |
| JP2002538814A (ja) | 2002-11-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |