ATE405283T1 - Hemmung der atf2-aktivität zur behandlung von krebs - Google Patents

Hemmung der atf2-aktivität zur behandlung von krebs

Info

Publication number
ATE405283T1
ATE405283T1 AT02707837T AT02707837T ATE405283T1 AT E405283 T1 ATE405283 T1 AT E405283T1 AT 02707837 T AT02707837 T AT 02707837T AT 02707837 T AT02707837 T AT 02707837T AT E405283 T1 ATE405283 T1 AT E405283T1
Authority
AT
Austria
Prior art keywords
atf2
therapies
inhibition
treat cancer
provides methods
Prior art date
Application number
AT02707837T
Other languages
English (en)
Inventor
Ev Ronai Ze
Original Assignee
Sinai School Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sinai School Medicine filed Critical Sinai School Medicine
Application granted granted Critical
Publication of ATE405283T1 publication Critical patent/ATE405283T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
AT02707837T 2001-02-15 2002-02-14 Hemmung der atf2-aktivität zur behandlung von krebs ATE405283T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26911801P 2001-02-15 2001-02-15
US26925701P 2001-02-16 2001-02-16

Publications (1)

Publication Number Publication Date
ATE405283T1 true ATE405283T1 (de) 2008-09-15

Family

ID=26953513

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02707837T ATE405283T1 (de) 2001-02-15 2002-02-14 Hemmung der atf2-aktivität zur behandlung von krebs

Country Status (6)

Country Link
US (2) US7314855B2 (de)
EP (1) EP1368049B1 (de)
AT (1) ATE405283T1 (de)
AU (1) AU2002242214A1 (de)
DE (1) DE60228419D1 (de)
WO (1) WO2002064025A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004064785A2 (en) * 2003-01-14 2004-08-05 Dana Farber Cancer Institute Cancer therapy sensitizer
EP1809315B1 (de) * 2004-10-18 2009-07-01 The Mount Sinai School of Medicine of New York University Hemmung des tumorwachstums und der metastasenbildung mit von atf2 stammenden peptiden
CN101090730B (zh) * 2004-11-09 2012-09-12 切尔泰克生物科学有限公司 增加癌细胞程序性细胞死亡的组合物和方法
WO2009026163A1 (en) * 2007-08-17 2009-02-26 Burnham Institute For Medical Research Compositions and methods for inhibiting growth and metastasis of melanoma
US20130225503A1 (en) * 2009-09-30 2013-08-29 Baylor Licnensing Group Tex14 peptides as novel antitumor agents
WO2012012710A2 (en) * 2010-07-22 2012-01-26 The Johns Hopkins University Radiation sensitization agents for prostate cancer
US20120095078A1 (en) * 2010-10-07 2012-04-19 Sanford-Burnham Medical Research Institute Methods of diagnosis and treatment of melanoma
CN106420712B (zh) * 2015-08-10 2020-09-25 上海市中医老年医学研究所 茴香霉素在制备预防/治疗卵巢癌药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5736381A (en) * 1995-05-19 1998-04-07 Davis; Roger J. Cytokine-, stress-, and oncoprotein-activated human protein kinase kinases
CA2291451A1 (en) * 1997-05-28 1998-12-03 Daniel A. Mercola Inhibition of stress activated protein kinase (sapk) pathway and sensitization of cells to cancer therapies
US6022952A (en) * 1998-04-01 2000-02-08 University Of Alberta Compositions and methods for protein secretion

Also Published As

Publication number Publication date
AU2002242214A1 (en) 2002-08-28
WO2002064025A3 (en) 2002-12-19
US7935525B2 (en) 2011-05-03
US7314855B2 (en) 2008-01-01
EP1368049B1 (de) 2008-08-20
US20080139475A1 (en) 2008-06-12
DE60228419D1 (de) 2008-10-02
WO2002064025A2 (en) 2002-08-22
EP1368049A2 (de) 2003-12-10
EP1368049A4 (de) 2004-09-08
US20020169121A1 (en) 2002-11-14

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Legal Events

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