ATE401394T1 - Verbesserte dnase flüssige lösungen - Google Patents
Verbesserte dnase flüssige lösungenInfo
- Publication number
- ATE401394T1 ATE401394T1 AT95911123T AT95911123T ATE401394T1 AT E401394 T1 ATE401394 T1 AT E401394T1 AT 95911123 T AT95911123 T AT 95911123T AT 95911123 T AT95911123 T AT 95911123T AT E401394 T1 ATE401394 T1 AT E401394T1
- Authority
- AT
- Austria
- Prior art keywords
- dnase
- solutions
- calcium ion
- liquid solutions
- thermal aggregation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/21—Endodeoxyribonucleases producing 5'-phosphomonoesters (3.1.21)
- C12Y301/21001—Deoxyribonuclease I (3.1.21.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Botany (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Enzymes And Modification Thereof (AREA)
- Jellies, Jams, And Syrups (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20650494A | 1994-03-04 | 1994-03-04 | |
US37752795A | 1995-01-20 | 1995-01-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE401394T1 true ATE401394T1 (de) | 2008-08-15 |
Family
ID=26901408
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95911123T ATE401394T1 (de) | 1994-03-04 | 1995-02-28 | Verbesserte dnase flüssige lösungen |
Country Status (7)
Country | Link |
---|---|
US (2) | US6383788B1 (de) |
EP (1) | EP0748377B1 (de) |
JP (1) | JP3009224B2 (de) |
AT (1) | ATE401394T1 (de) |
CA (1) | CA2184581C (de) |
DE (1) | DE69535787D1 (de) |
WO (1) | WO1995023854A1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3009224B2 (ja) * | 1994-03-04 | 2000-02-14 | ジェネンテック インコーポレイテッド | 改良されたdnアーゼ液体溶液 |
AU733602B2 (en) * | 1996-09-04 | 2001-05-17 | Nexell Therapeutics Inc. | Compositions containing nucleases and chelators to enhance the recovery of cells during cell separating procedures |
SI1324776T2 (en) | 2000-10-12 | 2018-06-29 | Genentech, Inc. | Concentrated protein formulations with reduced viscosity |
US8703126B2 (en) | 2000-10-12 | 2014-04-22 | Genentech, Inc. | Reduced-viscosity concentrated protein formulations |
SG174258A1 (en) | 2009-03-06 | 2011-10-28 | Genentech Inc | Antibody formulation |
JP5921545B2 (ja) | 2010-08-11 | 2016-05-24 | アイアンウッド ファーマシューティカルズ インコーポレイテッド | リナクロチドの安定な製剤 |
WO2016067944A1 (ja) | 2014-10-31 | 2016-05-06 | Jcrファーマ株式会社 | 組換えヒトDNaseIの製造方法 |
RU2017125957A (ru) * | 2015-01-04 | 2019-02-04 | Проталикс Лтд. | Модифицированная днказа и ее применения |
WO2017049205A2 (en) * | 2015-09-18 | 2017-03-23 | Amunix Operating Inc. | Growth hormone formulation |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3042587A (en) * | 1960-11-29 | 1962-07-03 | Merck & Co Inc | Stabilized desoxyribonuclease preparation |
CA1059937A (en) | 1975-03-25 | 1979-08-07 | Boen T. Khouw | Isolation and purification of deoxyribonuclease |
US4233405A (en) * | 1979-10-10 | 1980-11-11 | Rohm And Haas Company | Process for spray drying enzymes |
ATE176924T1 (de) * | 1988-12-23 | 1999-03-15 | Genentech Inc | Verfahren zur herstellung von menschlicher dnase |
US5279823A (en) * | 1992-06-08 | 1994-01-18 | Genentech, Inc. | Purified forms of DNASE |
JP3009224B2 (ja) * | 1994-03-04 | 2000-02-14 | ジェネンテック インコーポレイテッド | 改良されたdnアーゼ液体溶液 |
US5580856A (en) * | 1994-07-15 | 1996-12-03 | Prestrelski; Steven J. | Formulation of a reconstituted protein, and method and kit for the production thereof |
-
1995
- 1995-02-28 JP JP7522968A patent/JP3009224B2/ja not_active Expired - Lifetime
- 1995-02-28 WO PCT/US1995/002457 patent/WO1995023854A1/en active Application Filing
- 1995-02-28 US US08/696,955 patent/US6383788B1/en not_active Expired - Lifetime
- 1995-02-28 DE DE69535787T patent/DE69535787D1/de not_active Expired - Fee Related
- 1995-02-28 AT AT95911123T patent/ATE401394T1/de not_active IP Right Cessation
- 1995-02-28 CA CA002184581A patent/CA2184581C/en not_active Expired - Lifetime
- 1995-02-28 EP EP95911123A patent/EP0748377B1/de not_active Expired - Lifetime
-
2002
- 2002-02-12 US US10/076,213 patent/US7018825B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20030054532A1 (en) | 2003-03-20 |
DE69535787D1 (de) | 2008-08-28 |
EP0748377B1 (de) | 2008-07-16 |
US7018825B2 (en) | 2006-03-28 |
JP3009224B2 (ja) | 2000-02-14 |
WO1995023854A1 (en) | 1995-09-08 |
CA2184581C (en) | 2005-02-22 |
CA2184581A1 (en) | 1995-09-08 |
JPH09503394A (ja) | 1997-04-08 |
US6383788B1 (en) | 2002-05-07 |
EP0748377A1 (de) | 1996-12-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |