ATE398616T1 - Neue 4-aminochinolinderivate als antimalariamittel - Google Patents

Neue 4-aminochinolinderivate als antimalariamittel

Info

Publication number
ATE398616T1
ATE398616T1 AT06706532T AT06706532T ATE398616T1 AT E398616 T1 ATE398616 T1 AT E398616T1 AT 06706532 T AT06706532 T AT 06706532T AT 06706532 T AT06706532 T AT 06706532T AT E398616 T1 ATE398616 T1 AT E398616T1
Authority
AT
Austria
Prior art keywords
new
antimalariatic
agents
aminoquinoline derivatives
aminoquinoline
Prior art date
Application number
AT06706532T
Other languages
English (en)
Inventor
Fabio Sparatore
Original Assignee
Ctg Pharma S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ctg Pharma S R L filed Critical Ctg Pharma S R L
Application granted granted Critical
Publication of ATE398616T1 publication Critical patent/ATE398616T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT06706532T 2005-02-04 2006-02-01 Neue 4-aminochinolinderivate als antimalariamittel ATE398616T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05425051 2005-02-04

Publications (1)

Publication Number Publication Date
ATE398616T1 true ATE398616T1 (de) 2008-07-15

Family

ID=34943039

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06706532T ATE398616T1 (de) 2005-02-04 2006-02-01 Neue 4-aminochinolinderivate als antimalariamittel

Country Status (5)

Country Link
US (1) US20080262031A1 (de)
EP (1) EP1846401B1 (de)
AT (1) ATE398616T1 (de)
DE (1) DE602006001511D1 (de)
WO (1) WO2006082030A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1877055A4 (de) * 2005-05-06 2008-10-01 Apath Llc 4-aminochinolin-verbindungen zur behandlung von leiden in verbindung mit viren
US20120142731A1 (en) * 2007-10-31 2012-06-07 Functional Genetics, Inc. Methods of inhibiting viral infection
WO2015133280A1 (ja) * 2014-03-03 2015-09-11 公立大学法人名古屋市立大学 抗マラリア活性化合物及び抗マラリア薬

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3553228A (en) * 1967-09-26 1971-01-05 Colgate Palmolive Co 3-substituted-4h(1)benzopyrano(3,4-d) isoxazoles
US3948928A (en) * 1972-03-17 1976-04-06 Dainippon Pharmaceutical Co., Ltd. 3-Substituted-1,2-benzisoxazoles and pharmaceutically acceptable acid addition salts thereof
DE3462259D1 (de) * 1983-07-22 1987-03-05 Bayer Ag Substituted furazans
FR2677019B1 (fr) * 1991-05-27 1994-11-25 Pf Medicament Nouvelles piperidines disubstituees-1,4, leur preparation et leur application en therapeutique.
CA2133620A1 (en) * 1993-10-28 1995-04-29 Werner Hofheinz Aminoquinoline derivatives
FR2720396B1 (fr) * 1994-05-27 1996-06-28 Adir Nouveaux N-pyridyl carboxamides et dérivés leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
WO2001051456A2 (en) * 2000-01-13 2001-07-19 Tularik Inc. Antibacterial agents
GB0109122D0 (en) * 2001-04-11 2001-05-30 Smithkline Beecham Spa Novel compounds
US7598287B2 (en) * 2003-04-01 2009-10-06 Medical College Of Georgia Research Institute, Inc. Use of inhibitors of indoleamine-2,3-dioxygenase in combination with other therapeutic modalities
ITMI20032044A1 (it) * 2003-10-21 2005-04-22 Univ Degli Studi Milano Chinolizidinil e chinolizidinilalchil-derivati della 4-ammino-chinolina ad attivita' antimalarica
US7935700B2 (en) * 2004-09-08 2011-05-03 Mitsubishi Tanabe Pharma Corporation Morpholine compound
US7429667B2 (en) * 2005-01-20 2008-09-30 Ardea Biosciences, Inc. Phenylamino isothiazole carboxamidines as MEK inhibitors
DK2559690T3 (en) * 2005-05-10 2016-04-25 Incyte Holdings Corp Modulators of indoleamine 2,3-dioxygenase and methods of use thereof
TWI382974B (zh) * 2005-12-20 2013-01-21 Incyte Corp 作為吲哚胺２，３-二氧化酶調節劑之ｎ-羥基甲脒基雜環化物
US20070203140A1 (en) * 2006-02-09 2007-08-30 Combs Andrew P N-hydroxyguanidines as modulators of indoleamine 2,3-dioxygenase
US20080119491A1 (en) * 2006-09-19 2008-05-22 Incyte Corporation Amidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
WO2008036652A2 (en) * 2006-09-19 2008-03-27 Incyte Corporation Amidines as modulators of indoleamine 2,3-dioxygenase
JP5319532B2 (ja) * 2006-09-19 2013-10-16 インサイト・コーポレイション インドールアミン２，３−ジオキシゲナーゼのモジュレーターとしてのｎ−ヒドロキシアミジノヘテロサイクル

Also Published As

Publication number Publication date
WO2006082030A1 (en) 2006-08-10
EP1846401B1 (de) 2008-06-18
US20080262031A1 (en) 2008-10-23
EP1846401A1 (de) 2007-10-24
DE602006001511D1 (de) 2008-07-31

Similar Documents

Publication Publication Date Title
DE60234050D1 (de) PYRIDOi2,1-A ISOCHINOLINDERIVATIVE ALS DPP-IV-HEMMER
MY141780A (en) 5-substituted quinoline and isoquinoline derivatives, a method for the production thereof and their use as antiphlogistics
NO20064555L (no) HIV-integraseinhibitorer.
ATE495176T1 (de) Spiroindolinon-derivate
DE602006013025D1 (de) Hiv-integrasehemmer
RS86804A (en) Quinoline and isoquinoline derivatives method for the production thereof and use therof as anti-inflammatory agents
ATE422198T1 (de) Arylsulfonylnaphthalinderivate als 5ht2a- antagonisten
ATE392897T1 (de) Chinolinderivate als npy antagonisten
ATE489387T1 (de) Pyridoä2,1-aü-isochinolinderivate als dpp-iv inhibitoren
DE502006004750D1 (de) 2,4-diamino-pyrimidine als aurora inhibitoren
NL1028192A1 (nl) Gesubstitueerde chinolineverbindingen.
SMAP200800029A (it) 2-ammino-7,8-diidro-6h.pirido[4,3-d]pirimidin-5-oni
MX2007004738A (es) Inhibidores de mif.
DE602007004999D1 (de) 1,4,5,6,7,8-hexahydro-1,2,5-triaza-azulen-derivate als orexinrezeptor-antagonisten
ATE552834T1 (de) Zubereitung von 1,6-disubstituierten azabenzimidazolen als kinasehemmer
DK1421075T3 (da) Piperidinderivater, der er nyttige som CCR5-antagonister til behandling af HIV
TW200619205A (en) A method for preparing irbesartan and intermediates thereof
ATE438398T1 (de) Pyrrolo-dihydroisochinolin-derivate als pde10- inhibitoren
ATE398616T1 (de) Neue 4-aminochinolinderivate als antimalariamittel
DE602006008937D1 (de) N-amidderivate von 8-azabicycloä3.2.1üoct-3-yl als ccr1-antagonisten
DE60230491D1 (de) Als ccr5-antagonisten verwendbare aryloxim-piperazine
DE602006003347D1 (de) Farblose wasserlösliche organische leuchtstoffe und zwischenprodukte davon
ATE508130T1 (de) 3-oxa-10-aza-phenanthrene als pde4- oder pde3/4- inhibitoren
WO2006009696A3 (en) Anticoagulant contrast media
ATE489368T1 (de) Pyrimidinonverbindungen als calcilytica

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties