ATE393819T1 - Verwendungen von immortalisierten, homozygoten stat1-defizienten säugerzelllinien - Google Patents

Verwendungen von immortalisierten, homozygoten stat1-defizienten säugerzelllinien

Info

Publication number
ATE393819T1
ATE393819T1 AT98957581T AT98957581T ATE393819T1 AT E393819 T1 ATE393819 T1 AT E393819T1 AT 98957581 T AT98957581 T AT 98957581T AT 98957581 T AT98957581 T AT 98957581T AT E393819 T1 ATE393819 T1 AT E393819T1
Authority
AT
Austria
Prior art keywords
immortalized
stat1
cell lines
homozygot
interferons
Prior art date
Application number
AT98957581T
Other languages
English (en)
Inventor
David Levy
Peter Palese
Adolfo Garcia-Sastre
Joan Durbin
Original Assignee
Univ New York
Sinai School Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York, Sinai School Medicine filed Critical Univ New York
Application granted granted Critical
Publication of ATE393819T1 publication Critical patent/ATE393819T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151—Methods of production or purification of viral material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
AT98957581T 1997-11-03 1998-11-02 Verwendungen von immortalisierten, homozygoten stat1-defizienten säugerzelllinien ATE393819T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/962,740 US6740519B1 (en) 1997-11-03 1997-11-03 Immortalized, homozygous stat1-deficient mammalian cell lines and their uses

Publications (1)

Publication Number Publication Date
ATE393819T1 true ATE393819T1 (de) 2008-05-15

Family

ID=25506285

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98957581T ATE393819T1 (de) 1997-11-03 1998-11-02 Verwendungen von immortalisierten, homozygoten stat1-defizienten säugerzelllinien

Country Status (7)

Country Link
US (1) US6740519B1 (de)
EP (1) EP1034254B1 (de)
AT (1) ATE393819T1 (de)
AU (1) AU1380899A (de)
CA (1) CA2309114C (de)
DE (1) DE69839429D1 (de)
WO (1) WO1999023203A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1950313A3 (de) 2000-03-27 2010-12-08 GlaxoSmithKline LLC Detektion von lebensfähigen Agenzien
CA2416633C (en) 2000-08-04 2013-04-30 Chiron Corporation Enhanced replication of hcv rna

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4071618A (en) 1974-09-03 1978-01-31 Research Foundation For Microbial Diseases Of Osaka University Process for preparing virus disease live vaccines
US5087571A (en) * 1984-06-22 1992-02-11 President And Fellows Of Harvard College Method for providing a cell culture from a transgenic non-human mammal
IL88377A (en) 1988-11-14 1996-09-12 Yeda Res & Dev Cloning and expression of a protein which modulates cellular response to type I interferon
FR2650838A1 (fr) * 1989-08-09 1991-02-15 Transgene Sa Vecteurs d'expression du facteur ix dans une cellule eucaryote superieure, procede de preparation de facteur ix par des animaux transgeniques et facteur ix obtenu
AU7795094A (en) 1993-09-15 1995-04-03 New York University Dna sequence which binds transcriptional regulatory proteins activated in response to various cytokines and uses thereof
US5840565A (en) 1995-08-22 1998-11-24 The Regents Of The University Of California Methods for enhancing the production of viral vaccines in PKR-deficient cell culture

Also Published As

Publication number Publication date
US6740519B1 (en) 2004-05-25
WO1999023203A1 (en) 1999-05-14
EP1034254A4 (de) 2001-03-14
CA2309114A1 (en) 1999-05-14
EP1034254A1 (de) 2000-09-13
EP1034254B1 (de) 2008-04-30
CA2309114C (en) 2013-02-12
DE69839429D1 (de) 2008-06-12
AU1380899A (en) 1999-05-24

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Legal Events

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