ATE375405T1 - Diagnose abnormaler blutzustände basierend auf polymorphismen des glycoprotein vi gens - Google Patents

Diagnose abnormaler blutzustände basierend auf polymorphismen des glycoprotein vi gens

Info

Publication number
ATE375405T1
ATE375405T1 AT03725431T AT03725431T ATE375405T1 AT E375405 T1 ATE375405 T1 AT E375405T1 AT 03725431 T AT03725431 T AT 03725431T AT 03725431 T AT03725431 T AT 03725431T AT E375405 T1 ATE375405 T1 AT E375405T1
Authority
AT
Austria
Prior art keywords
diagnosis
polymorphisms
glycoprotein
gene
abnormal blood
Prior art date
Application number
AT03725431T
Other languages
English (en)
Inventor
Willem Ouwehand
Peter Smethurst
Richard Farndale
Original Assignee
Willem Ouwehand
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Willem Ouwehand filed Critical Willem Ouwehand
Application granted granted Critical
Publication of ATE375405T1 publication Critical patent/ATE375405T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT03725431T 2002-05-22 2003-05-22 Diagnose abnormaler blutzustände basierend auf polymorphismen des glycoprotein vi gens ATE375405T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0211750.5A GB0211750D0 (en) 2002-05-22 2002-05-22 Abnormal blood conditions

Publications (1)

Publication Number Publication Date
ATE375405T1 true ATE375405T1 (de) 2007-10-15

Family

ID=9937168

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03725431T ATE375405T1 (de) 2002-05-22 2003-05-22 Diagnose abnormaler blutzustände basierend auf polymorphismen des glycoprotein vi gens

Country Status (8)

Country Link
US (1) US7855050B2 (de)
EP (1) EP1511859B1 (de)
AT (1) ATE375405T1 (de)
AU (1) AU2003227963B2 (de)
CA (1) CA2525646A1 (de)
DE (1) DE60316799T2 (de)
GB (1) GB0211750D0 (de)
WO (1) WO2003097875A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1369128A1 (de) 2002-06-07 2003-12-10 Procorde GmbH Glycoprotein VI Inhibitoren und deren therapeutische Verwendung
US20070071744A1 (en) 2002-06-07 2007-03-29 Gotz Munch Agents which bind to epitopes of glycoprotein VI
US7531178B2 (en) 2002-06-07 2009-05-12 Trigen Gmbh Immunoadhesin comprising a glycoprotein VI domain
GB0713364D0 (en) * 2007-07-10 2007-08-22 Europ Cardiovascular Genetics Abnormal blood conditions
RU2469322C1 (ru) * 2011-10-17 2012-12-10 Федеральное государственное учреждение "Кировский научно-исследовательский институт гематологии и переливания крови Федерального медико-биологического агентства" Способ прогнозирования риска развития ингибиторной формы гемофилии а
WO2021222772A2 (en) * 2020-05-01 2021-11-04 The Johns Hopkins University Compositions and methods for coronavirus detection
CN116120421B (zh) * 2022-08-26 2026-04-03 湖南家辉生物技术有限公司 一种itga2b突变体蛋白、itga2b基因突变体、扩增引物组、检测试剂及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9806806D0 (en) 1998-03-30 1998-05-27 Univ Cambridge Tech Peptides and uses thereof
US6245527B1 (en) * 1999-06-30 2001-06-12 Millennium Pharmaceuticals, Inc. Nucleic acid molecules encoding glycoprotein VI and recombinant uses thereof
WO2001016321A1 (en) * 1999-09-01 2001-03-08 Otsuka Pharmaceutical Co., Ltd. Platelet membrane glycoprotein vi (gpvi) dna and protein sequences, and uses thereof
US6825323B2 (en) * 2001-01-10 2004-11-30 The United States Of America As Represented By The Secretary Of The Army Compositions for treatment of hemorrhaging with activated factor VIIa in combination with fibrinogen and methods of using same
US7135286B2 (en) * 2002-03-26 2006-11-14 Perlegen Sciences, Inc. Pharmaceutical and diagnostic business systems and methods

Also Published As

Publication number Publication date
GB0211750D0 (en) 2002-07-03
EP1511859B1 (de) 2007-10-10
US7855050B2 (en) 2010-12-21
AU2003227963B2 (en) 2009-05-07
WO2003097875A1 (en) 2003-11-27
AU2003227963A1 (en) 2003-12-02
DE60316799D1 (de) 2007-11-22
DE60316799T2 (de) 2008-07-17
US20050255470A1 (en) 2005-11-17
CA2525646A1 (en) 2003-11-27
EP1511859A1 (de) 2005-03-09

Similar Documents

Publication Publication Date Title
Mootha et al. Association and familial segregation of CTG18. 1 trinucleotide repeat expansion of TCF4 gene in Fuchs' endothelial corneal dystrophy
Ho Lee et al. The mannose‐binding lectin gene polymorphisms and systemic lupus erythematosus: two case–control studies and a meta‐analysis
Rybakowski et al. Functional polymorphism of the matrix metalloproteinase-9 (MMP-9) gene in schizophrenia
Montes et al. Analysis of the association of IL1B (C+ 3954T) and IL1RN (intron 2) polymorphisms with dental implant loss in a Brazilian population
Mastaglia et al. Novel mutation in the myelin protein zero gene in a family with intermediate hereditary motor and sensory neuropathy
Andia et al. Genetic analysis of the IL8 gene polymorphism (rs4073) in generalized aggressive periodontitis
Moschos et al. Polymorphism analysis of VSX1 and SOD1 genes in Greek patients with keratoconus
Ciccarese et al. Oropharyngeal lesions in pityriasis rosea
DE60316799D1 (de) Diagnose abnormaler blutzustände basierend auf polymorphismen des glycoprotein vi gens
Colombo et al. The BRCA2 c. 68‐7T> A variant is not pathogenic: A model for clinical calibration of spliceogenicity
Gazquez et al. MICA-STR A. 4 is associated with slower hearing loss progression in patients with Meniere’s disease
Happle Linear psoriasis and ILVEN: is lumping or splitting appropriate?
Yao et al. The time course of deafness and retinal degeneration in a Kunming mouse model for Usher syndrome
EP2287340A3 (de) Verfahren zur Diagnose und Behandlung einer Geisteskrankheit
Hong et al. Genetic analysis of CARD14 in non-familial pityriasis rubra pilaris: a case series
Guadarrama-Vallejo et al. The T allele of lysyl oxidase-like 1 rs41435250 is a novel risk factor for pseudoexfoliation syndrome and pseudoexfoliation glaucoma independently and through intragenic epistatic interaction
Dobkin et al. Fragile X prenatal analyses show full mutation females at high risk for mosaic Turner syndrome: fragile X leads to chromosome loss
GB0713364D0 (en) Abnormal blood conditions
Löppönen et al. Homozygous M34T mutation of the GJB2 gene associates with an autosomal recessive nonsyndromic sensorineural hearing impairment in Finnish families
Rankin et al. HOXA1 mutations are not a common cause of Möbius syndrome
Khasanov et al. Frequency of il 12b gene polymorphism among patients with chronic rhinosinusitis polyposis
Walder et al. Early neurodevelopment and psychosis risk: Role of neurohormones and biological sex in modulating genetic, prenatal and sensory processing factors in brain development.
Dória et al. Study of Met34Thr variant in nonsyndromic hearing loss in four Portuguese families
Moka et al. Novel Hermanksky-Pudlak Syndrome Type 6 Missense Variant Associated with Subclinical Oculocutaneous Albinism and Mild Bleeding
Das et al. Spectrum of genetic defects and phenotype-genotype correlation in dyserythropoietic anemias: Bench to bedside approach in the Indian scenario

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties