ATE371655T1 - Farnesyl-protein-transferaseinhibitoren - Google Patents
Farnesyl-protein-transferaseinhibitorenInfo
- Publication number
- ATE371655T1 ATE371655T1 AT01985496T AT01985496T ATE371655T1 AT E371655 T1 ATE371655 T1 AT E371655T1 AT 01985496 T AT01985496 T AT 01985496T AT 01985496 T AT01985496 T AT 01985496T AT E371655 T1 ATE371655 T1 AT E371655T1
- Authority
- AT
- Austria
- Prior art keywords
- transferas
- inhibitors
- farnesyl protein
- farnesyl
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25397100P | 2000-11-29 | 2000-11-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE371655T1 true ATE371655T1 (de) | 2007-09-15 |
Family
ID=22962414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01985496T ATE371655T1 (de) | 2000-11-29 | 2001-11-27 | Farnesyl-protein-transferaseinhibitoren |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6528523B2 (de) |
| EP (1) | EP1337522B1 (de) |
| JP (1) | JP2004514717A (de) |
| KR (1) | KR20030060939A (de) |
| CN (1) | CN1198816C (de) |
| AR (1) | AR035660A1 (de) |
| AT (1) | ATE371655T1 (de) |
| AU (2) | AU3514302A (de) |
| CA (1) | CA2429720C (de) |
| DE (1) | DE60130239T2 (de) |
| ES (1) | ES2291368T3 (de) |
| HK (1) | HK1054226A1 (de) |
| HU (1) | HUP0302104A2 (de) |
| IL (1) | IL155668A0 (de) |
| MX (1) | MXPA03004878A (de) |
| NZ (1) | NZ525572A (de) |
| PE (1) | PE20020635A1 (de) |
| TW (1) | TWI225058B (de) |
| WO (1) | WO2002044164A1 (de) |
| ZA (1) | ZA200303635B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2546727C (en) | 2003-11-20 | 2012-10-02 | Children's Hospital Medical Center | Gtpase inhibitors and methods of use |
| EP1920048A4 (de) | 2005-07-29 | 2009-12-09 | Childrens Hosp Medical Center | Gtase-hemmer und verwendungsverfahren und kristallstruktur von rac-1-gtase |
| WO2013166043A1 (en) | 2012-05-02 | 2013-11-07 | Children's Hospital Medical Center | Rejuvenation of precursor cells |
| US10028503B2 (en) | 2014-06-18 | 2018-07-24 | Children's Hospital Medical Center | Platelet storage methods and compositions for same |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE210653T1 (de) * | 1993-10-15 | 2001-12-15 | Schering Corp | Tricyclische sulfonamide-derivate zur inhibierung der g-protein funktion und fur die bekandlung von proliferativen erkrantungen |
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
| US6365588B1 (en) | 1993-10-15 | 2002-04-02 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| US5661152A (en) * | 1993-10-15 | 1997-08-26 | Schering Corporation | Tricyclic sulfonamide compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| US5684013A (en) | 1995-03-24 | 1997-11-04 | Schering Corporation | Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| US5700806A (en) | 1995-03-24 | 1997-12-23 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| US5801175A (en) | 1995-04-07 | 1998-09-01 | Schering Corporation | Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| US5874442A (en) | 1995-12-22 | 1999-02-23 | Schering-Plough Corporation | Tricyclic amides useful for inhibition of G-protein function and for treatment of proliferative disease |
| WO1997023478A1 (en) * | 1995-12-22 | 1997-07-03 | Schering Corporation | Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases |
| US5784442A (en) | 1996-02-02 | 1998-07-21 | Telefonaktiebologet Lm Ericsson (Publ) | System and method for real-time billing in a radio telecommunications network |
| US5925757A (en) * | 1996-07-26 | 1999-07-20 | Schering Corporation | Method for preparing carboxamides |
| US5945429A (en) | 1996-09-13 | 1999-08-31 | Schering Corporation | Compounds useful for inhibition of farnesyl protein transferase |
| US6071907A (en) | 1996-09-13 | 2000-06-06 | Schering Corporation | Tricyclic compounds useful as FPT inhibitors |
| US6030982A (en) | 1996-09-13 | 2000-02-29 | Schering Corporationm | Compounds useful for inhibition of farnesyl protein transferase |
| US6040305A (en) | 1996-09-13 | 2000-03-21 | Schering Corporation | Compounds useful for inhibition of farnesyl protein transferase |
| US5985879A (en) | 1996-09-13 | 1999-11-16 | Schering Corporation | Compounds useful for inhibition of farnesyl protein transferase |
| US5861395A (en) | 1996-09-13 | 1999-01-19 | Schering Corporation | Compounds useful for inhibition of farnesyl proteins transferase |
| US6358968B1 (en) | 1997-06-17 | 2002-03-19 | Schering Corporation | N-substituted urea inhibitors of farnesyl-protein transferase |
| US6051582A (en) | 1997-06-17 | 2000-04-18 | Schering Corporation | Compounds useful for inhibition of farnesyl protein transferase |
| WO1998057949A1 (en) * | 1997-06-17 | 1998-12-23 | Schering Corporation | Novel tricyclic sulfonamide inhibitors of farnesyl-protein transferase |
| US6159984A (en) | 1997-06-17 | 2000-12-12 | Schering Corporation | Farnesyl protein transferase inhibitors |
| US6228865B1 (en) | 1997-06-17 | 2001-05-08 | Schering Corporation | Compounds useful for inhibition of farnesyl protein transferase |
| US5939416A (en) | 1997-06-17 | 1999-08-17 | Schering Corporation | Benzo (5,6) cycloheptapyridine compounds useful as farnesyl protein transferase inhibitors |
| US5925639A (en) | 1997-06-17 | 1999-07-20 | Schering Corporation | Keto amide derivatives useful as farnesyl protein transferase inhibitors |
| NZ501618A (en) * | 1997-06-17 | 2001-10-26 | Schering Corp | Benzo(5,6) cyclohepta(1,2-b)pyridine derivatives and their use as inhibitors of abnormal cell growth (e.g. cancer) and as inhibitors of farnesyl protein transferase |
| US6239140B1 (en) | 1997-06-17 | 2001-05-29 | Schering Corporation | Compounds useful for inhibition of farnesyl protein transferase |
| US5852034A (en) | 1997-06-17 | 1998-12-22 | Schering Corporation | Benzo(5,6)cycloheptapyridine cyclic ureas and lactams useful as farnesyl protein transferase inhibitors |
| US6211193B1 (en) | 1997-06-17 | 2001-04-03 | Schering Corporation | Compounds useful for inhibition of farnesyl protein transferase |
| US6221322B1 (en) | 1997-11-27 | 2001-04-24 | Dowa Mining Co., Ltd | Strontium nitrate and method for manufacturing same |
| US6096757A (en) | 1998-12-21 | 2000-08-01 | Schering Corporation | Method for treating proliferative diseases |
| US6372747B1 (en) | 1998-12-18 | 2002-04-16 | Schering Corporation | Farnesyl protein transferase inhibitors |
| US6362188B1 (en) | 1998-12-18 | 2002-03-26 | Schering Corporation | Farnesyl protein transferase inhibitors |
| US6432959B1 (en) | 1998-12-23 | 2002-08-13 | Schering Corporation | Inhibitors of farnesyl-protein transferase |
| US6410451B2 (en) | 1999-09-27 | 2002-06-25 | Lam Research Corporation | Techniques for improving etching in a plasma processing chamber |
-
2001
- 2001-11-27 US US09/995,156 patent/US6528523B2/en not_active Expired - Fee Related
- 2001-11-27 EP EP01985496A patent/EP1337522B1/de not_active Expired - Lifetime
- 2001-11-27 AU AU3514302A patent/AU3514302A/xx active Pending
- 2001-11-27 AR ARP010105505A patent/AR035660A1/es unknown
- 2001-11-27 PE PE2001001188A patent/PE20020635A1/es not_active Application Discontinuation
- 2001-11-27 CA CA002429720A patent/CA2429720C/en not_active Expired - Fee Related
- 2001-11-27 AU AU2002235143A patent/AU2002235143B2/en not_active Ceased
- 2001-11-27 KR KR10-2003-7006749A patent/KR20030060939A/ko not_active Application Discontinuation
- 2001-11-27 DE DE60130239T patent/DE60130239T2/de not_active Expired - Lifetime
- 2001-11-27 ES ES01985496T patent/ES2291368T3/es not_active Expired - Lifetime
- 2001-11-27 CN CNB018194605A patent/CN1198816C/zh not_active Expired - Fee Related
- 2001-11-27 MX MXPA03004878A patent/MXPA03004878A/es active IP Right Grant
- 2001-11-27 WO PCT/US2001/044333 patent/WO2002044164A1/en active IP Right Grant
- 2001-11-27 HU HU0302104A patent/HUP0302104A2/hu unknown
- 2001-11-27 IL IL15566801A patent/IL155668A0/xx unknown
- 2001-11-27 NZ NZ525572A patent/NZ525572A/en unknown
- 2001-11-27 JP JP2002546534A patent/JP2004514717A/ja active Pending
- 2001-11-27 AT AT01985496T patent/ATE371655T1/de not_active IP Right Cessation
- 2001-11-28 TW TW090129431A patent/TWI225058B/zh not_active IP Right Cessation
-
2003
- 2003-05-12 ZA ZA200303635A patent/ZA200303635B/en unknown
- 2003-09-09 HK HK03106385.7A patent/HK1054226A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1476444A (zh) | 2004-02-18 |
| CN1198816C (zh) | 2005-04-27 |
| NZ525572A (en) | 2004-11-26 |
| PE20020635A1 (es) | 2002-07-11 |
| ZA200303635B (en) | 2004-08-12 |
| TWI225058B (en) | 2004-12-11 |
| CA2429720C (en) | 2009-12-29 |
| AR035660A1 (es) | 2004-06-23 |
| KR20030060939A (ko) | 2003-07-16 |
| HK1054226A1 (zh) | 2003-11-21 |
| HUP0302104A2 (hu) | 2003-09-29 |
| CA2429720A1 (en) | 2002-06-06 |
| DE60130239D1 (en) | 2007-10-11 |
| DE60130239T2 (de) | 2008-05-21 |
| JP2004514717A (ja) | 2004-05-20 |
| ES2291368T3 (es) | 2008-03-01 |
| WO2002044164A1 (en) | 2002-06-06 |
| AU3514302A (en) | 2002-06-11 |
| MXPA03004878A (es) | 2003-08-19 |
| IL155668A0 (en) | 2003-11-23 |
| EP1337522B1 (de) | 2007-08-29 |
| AU2002235143B2 (en) | 2006-03-02 |
| US20020115679A1 (en) | 2002-08-22 |
| EP1337522A1 (de) | 2003-08-27 |
| US6528523B2 (en) | 2003-03-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |