ATE367829T1 - Verbesserungen in oder bezüglich zu diagnostische/therapeutische mittel - Google Patents
Verbesserungen in oder bezüglich zu diagnostische/therapeutische mittelInfo
- Publication number
- ATE367829T1 ATE367829T1 AT99918154T AT99918154T ATE367829T1 AT E367829 T1 ATE367829 T1 AT E367829T1 AT 99918154 T AT99918154 T AT 99918154T AT 99918154 T AT99918154 T AT 99918154T AT E367829 T1 ATE367829 T1 AT E367829T1
- Authority
- AT
- Austria
- Prior art keywords
- diagnostic
- therapeutic agents
- relating
- lipopeptides
- carbon atoms
- Prior art date
Links
- 239000000032 diagnostic agent Substances 0.000 title abstract 2
- 229940039227 diagnostic agent Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 229940124597 therapeutic agent Drugs 0.000 title abstract 2
- 108010028921 Lipopeptides Proteins 0.000 abstract 2
- 125000000266 alpha-aminoacyl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 239000002961 echo contrast media Substances 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1806—Suspensions, emulsions, colloids, dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/927—Diagnostic contrast agent
- Y10S977/928—X-ray agent
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/927—Diagnostic contrast agent
- Y10S977/929—Ultrasound contrast agent
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/927—Diagnostic contrast agent
- Y10S977/93—MRI contrast agent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acoustics & Sound (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9809084.8A GB9809084D0 (en) | 1998-04-28 | 1998-04-28 | Improvements in or relating to diagnostic/therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE367829T1 true ATE367829T1 (de) | 2007-08-15 |
Family
ID=10831133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99918154T ATE367829T1 (de) | 1998-04-28 | 1999-04-22 | Verbesserungen in oder bezüglich zu diagnostische/therapeutische mittel |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1073475B1 (de) |
| JP (1) | JP2002512986A (de) |
| KR (1) | KR20010043080A (de) |
| CN (1) | CN1302211A (de) |
| AT (1) | ATE367829T1 (de) |
| AU (1) | AU763191B2 (de) |
| CA (1) | CA2329778A1 (de) |
| DE (1) | DE69936641T2 (de) |
| GB (1) | GB9809084D0 (de) |
| IL (1) | IL139112A0 (de) |
| WO (1) | WO1999055383A2 (de) |
| ZA (1) | ZA200005952B (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2376650C (en) | 1999-06-29 | 2008-01-15 | University Health Network | Peptide conjugates for the stabilization of membrane proteins and interactions with biological membranes |
| DE19935302A1 (de) | 1999-07-28 | 2001-02-08 | Aventis Pharma Gmbh | Konjugate und Verfahren zu deren Herstellung sowie deren Verwendung zum Transport von Molekülen über biologische Membranen |
| AU2002365162A1 (en) | 2001-11-14 | 2003-07-09 | Northwestern University | Self-assembly and mineralization of peptide-amphiphile nanofibers |
| US7371719B2 (en) | 2002-02-15 | 2008-05-13 | Northwestern University | Self-assembly of peptide-amphiphile nanofibers under physiological conditions |
| US7794693B2 (en) | 2002-03-01 | 2010-09-14 | Bracco International B.V. | Targeting vector-phospholipid conjugates |
| US7261876B2 (en) | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
| US8623822B2 (en) | 2002-03-01 | 2014-01-07 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
| US20050100963A1 (en) | 2002-03-01 | 2005-05-12 | Dyax Corporation | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
| US7554021B2 (en) | 2002-11-12 | 2009-06-30 | Northwestern University | Composition and method for self-assembly and mineralization of peptide amphiphiles |
| AU2003298647A1 (en) | 2002-11-14 | 2004-06-15 | Claussen, Randal, C. | Synthesis and self-assembly of abc triblock bola peptide |
| US9364569B2 (en) | 2003-02-04 | 2016-06-14 | Bracco Suisse S.A. | Ultrasound contrast agents and process for the preparation thereof |
| CA2549164A1 (en) | 2003-12-05 | 2005-06-23 | Northwestern University | Self-assembling peptide amphiphiles and related methods for growth factor delivery |
| WO2005063305A1 (en) | 2003-12-22 | 2005-07-14 | Bracco Research Sa | Gas-filled microvesicle assembly for contrast imaging |
| JP4773430B2 (ja) | 2004-06-03 | 2011-09-14 | ブラッコ・リサーチ・ソシエテ・アノニム | 治療および／または診断用途のためのリポソーム集合体 |
| EP1784228B1 (de) | 2004-08-18 | 2016-10-05 | Bracco Suisse SA | Gasgefüllte mikrovesikelzusammensetzung für kontrastbilddarstellungen |
| CA2598251A1 (en) | 2005-03-04 | 2006-09-14 | Northwestern University | Angiogenic heparin binding peptide amphiphiles |
| EP1714642A1 (de) | 2005-04-18 | 2006-10-25 | Bracco Research S.A. | Pharmazeutische Formulierung mit gasgefüllten Mikrokapseln zur ultraschallgesteuerten Freisetzung |
| CN100402092C (zh) * | 2005-06-07 | 2008-07-16 | 西安交通大学 | 血栓诊断和/或治疗用含气干粉活性剂及其制备工艺 |
| EP1966388B1 (de) * | 2005-12-09 | 2013-08-07 | Bracco Suisse SA | Konjugate aus zielspezifischen vektoren und phospholipiden |
| WO2007143006A2 (en) * | 2006-06-01 | 2007-12-13 | Therapeutic Peptides, Inc. | Polymeric biosurfactants |
| EP2061517B1 (de) | 2006-09-05 | 2010-06-02 | Bracco Research S.A. | Gasgefüllte mikrovesikel mit polymer-modifizierten lipiden |
| US8076295B2 (en) | 2007-04-17 | 2011-12-13 | Nanotope, Inc. | Peptide amphiphiles having improved solubility and methods of using same |
| CN102387772A (zh) * | 2008-05-29 | 2012-03-21 | 唐纳德·欧文 | 皮肤美容组合物中的寡聚生物表面活性剂 |
| WO2010120830A1 (en) | 2009-04-13 | 2010-10-21 | Northwestern University | Novel peptide-based scaffolds for cartilage regeneration and methods for their use |
| CN105026030B (zh) | 2012-12-21 | 2017-04-12 | 博莱科瑞士股份有限公司 | 充气微泡 |
| KR102056948B1 (ko) * | 2018-02-05 | 2019-12-17 | 주식회사 빌릭스 | 빌리루빈 유도체 기반의 진단 및 치료용 초음파 조영제 |
| US20200360289A1 (en) | 2019-05-15 | 2020-11-19 | Bracco Suisse Sa | Freeze-dried product and gas-filled microvesicles suspension |
| US11717570B2 (en) | 2019-05-15 | 2023-08-08 | Bracco Suisse Sa | Gas-filled microvesicles |
| CN111658304B (zh) * | 2020-06-29 | 2022-03-15 | 北京中关村水木医疗科技有限公司 | 下位机的控制方法、下位机及可读介质 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5776429A (en) * | 1989-12-22 | 1998-07-07 | Imarx Pharmaceutical Corp. | Method of preparing gas-filled microspheres using a lyophilized lipids |
| US5580575A (en) * | 1989-12-22 | 1996-12-03 | Imarx Pharmaceutical Corp. | Therapeutic drug delivery systems |
| US5228446A (en) * | 1989-12-22 | 1993-07-20 | Unger Evan C | Gas filled liposomes and their use as ultrasonic contrast agents |
| IL128345A (en) * | 1996-08-02 | 2003-06-24 | Amersham Health As | Enhanced contrast agent for ultrasound imaging of the liver |
| WO1998018498A2 (en) * | 1996-10-28 | 1998-05-07 | Marsden, John, Christopher | Improvements in or relating to diagnostic/therapeutic agents |
| WO1998018497A2 (en) * | 1996-10-28 | 1998-05-07 | Nycomed Imaging As | Contrast agents |
| WO1998018495A2 (en) * | 1996-10-28 | 1998-05-07 | Marsden, John, Christopher | Improvements in or relating to diagnostic/therapeutic agents |
-
1998
- 1998-04-28 GB GBGB9809084.8A patent/GB9809084D0/en not_active Ceased
-
1999
- 1999-04-22 WO PCT/GB1999/001247 patent/WO1999055383A2/en active IP Right Grant
- 1999-04-22 AT AT99918154T patent/ATE367829T1/de not_active IP Right Cessation
- 1999-04-22 CN CN99806552A patent/CN1302211A/zh active Pending
- 1999-04-22 IL IL13911299A patent/IL139112A0/xx unknown
- 1999-04-22 AU AU36187/99A patent/AU763191B2/en not_active Ceased
- 1999-04-22 JP JP2000545579A patent/JP2002512986A/ja not_active Withdrawn
- 1999-04-22 CA CA002329778A patent/CA2329778A1/en not_active Abandoned
- 1999-04-22 DE DE69936641T patent/DE69936641T2/de not_active Expired - Fee Related
- 1999-04-22 KR KR1020007011961A patent/KR20010043080A/ko not_active Application Discontinuation
- 1999-04-22 EP EP99918154A patent/EP1073475B1/de not_active Expired - Lifetime
-
2000
- 2000-10-24 ZA ZA200005952A patent/ZA200005952B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1073475A2 (de) | 2001-02-07 |
| ZA200005952B (en) | 2001-05-07 |
| DE69936641T2 (de) | 2008-05-21 |
| EP1073475B1 (de) | 2007-07-25 |
| AU3618799A (en) | 1999-11-16 |
| DE69936641D1 (de) | 2007-09-06 |
| CN1302211A (zh) | 2001-07-04 |
| IL139112A0 (en) | 2001-11-25 |
| GB9809084D0 (en) | 1998-06-24 |
| JP2002512986A (ja) | 2002-05-08 |
| CA2329778A1 (en) | 1999-11-04 |
| WO1999055383A3 (en) | 2000-07-06 |
| AU763191B2 (en) | 2003-07-17 |
| WO1999055383A2 (en) | 1999-11-04 |
| KR20010043080A (ko) | 2001-05-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |