ATE346596T1 - Behandlungsmethode von aknepatienten durch verabreichung von hemmern der cyclischen gmp pde - Google Patents

Behandlungsmethode von aknepatienten durch verabreichung von hemmern der cyclischen gmp pde

Info

Publication number
ATE346596T1
ATE346596T1 AT00904556T AT00904556T ATE346596T1 AT E346596 T1 ATE346596 T1 AT E346596T1 AT 00904556 T AT00904556 T AT 00904556T AT 00904556 T AT00904556 T AT 00904556T AT E346596 T1 ATE346596 T1 AT E346596T1
Authority
AT
Austria
Prior art keywords
administration
treatment method
cyclic gmp
pde inhibitors
acne patients
Prior art date
Application number
AT00904556T
Other languages
English (en)
Inventor
Kerstin B Menander
Mark Jeffrey Mayle
Original Assignee
Osi Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/239,840 external-priority patent/US6025394A/en
Application filed by Osi Pharm Inc filed Critical Osi Pharm Inc
Application granted granted Critical
Publication of ATE346596T1 publication Critical patent/ATE346596T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
AT00904556T 1999-01-29 2000-01-25 Behandlungsmethode von aknepatienten durch verabreichung von hemmern der cyclischen gmp pde ATE346596T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/239,840 US6025394A (en) 1999-01-29 1999-01-29 Method for treating patients with acne by administering substituted sulfonyl indenyl acetic acids, amides and alcohols
US09/378,660 US6177471B1 (en) 1999-01-29 1999-08-20 Method for treating patients with acne by administering a CGMP-specific PDE inhibitor

Publications (1)

Publication Number Publication Date
ATE346596T1 true ATE346596T1 (de) 2006-12-15

Family

ID=26932928

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00904556T ATE346596T1 (de) 1999-01-29 2000-01-25 Behandlungsmethode von aknepatienten durch verabreichung von hemmern der cyclischen gmp pde

Country Status (9)

Country Link
EP (1) EP1146866B1 (de)
JP (1) JP2002535361A (de)
AT (1) ATE346596T1 (de)
AU (1) AU2629500A (de)
CA (1) CA2360676C (de)
DE (1) DE60032114T2 (de)
DK (1) DK1146866T3 (de)
ES (1) ES2277828T3 (de)
WO (1) WO2000044372A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006054005A1 (de) * 2006-11-16 2008-05-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Polymorphe von 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester
CN111233706A (zh) * 2020-01-19 2020-06-05 安徽峆一药业股份有限公司 一种舒林酸的绿色合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3532752A (en) * 1965-12-30 1970-10-06 Merck & Co Inc 1-alkylidene-3-indenyl aliphatic amines
US5500230A (en) * 1987-01-23 1996-03-19 The General Hospital Corporation Method for treatment of glaucoma with nitrogen containing guanylate cyclase activators
US5011843A (en) * 1988-05-31 1991-04-30 Iolab Corporation Treatment of glaucoma using phosphodiesterase inhibitors
US5229516A (en) * 1989-10-27 1993-07-20 American Home Products Corporation Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase
AU650720B2 (en) * 1991-03-08 1994-06-30 Fgn, Inc. Method for treating patients with precancerous lesions by administering substituted sulfonyl indenyl acetic and propionic acids and esters thereof
US5401774A (en) * 1991-03-08 1995-03-28 University Of Arizona Method for treating patients with precancerous lesions by administering substituted sulfonyl idenyl acetic and propionic acids and esters to patients with lesions sensitive to such compounds

Also Published As

Publication number Publication date
ES2277828T3 (es) 2007-08-01
AU2629500A (en) 2000-08-18
DE60032114D1 (de) 2007-01-11
EP1146866A4 (de) 2004-12-08
DK1146866T3 (da) 2007-04-02
EP1146866B1 (de) 2006-11-29
CA2360676A1 (en) 2000-08-03
JP2002535361A (ja) 2002-10-22
CA2360676C (en) 2008-12-23
DE60032114T2 (de) 2007-06-06
EP1146866A1 (de) 2001-10-24
WO2000044372A1 (en) 2000-08-03

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