ATE336T1 - STABILIZED PLATELET FACTOR 4 IMMUNASSAY CALIBRATION SOLUTIONS AND RADIOIMMUNASSAY METHODS. - Google Patents

STABILIZED PLATELET FACTOR 4 IMMUNASSAY CALIBRATION SOLUTIONS AND RADIOIMMUNASSAY METHODS.

Info

Publication number
ATE336T1
ATE336T1 AT79300880T AT79300880T ATE336T1 AT E336 T1 ATE336 T1 AT E336T1 AT 79300880 T AT79300880 T AT 79300880T AT 79300880 T AT79300880 T AT 79300880T AT E336 T1 ATE336 T1 AT E336T1
Authority
AT
Austria
Prior art keywords
platelet factor
immunassay
radioimmunassay
methods
stabilized
Prior art date
Application number
AT79300880T
Other languages
German (de)
Inventor
Erwin F. Jr. Workman
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25446555&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE336(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ATE336T1 publication Critical patent/ATE336T1/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/96Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
    • G01N2400/40Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/804Radioisotope, e.g. radioimmunoassay
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/826Additives, e.g. buffers, diluents, preservatives

Abstract

The present invention encompasses a stabilized platelet factor4 immunoassay standard comprising an aqueous solution containing 10 to 100ng/ml of platelet factor 4, carrier protein, and an effective stabilizing amount of heparin, as well as <sup>125</sup>llabeled platelet factor 4 reagent stabilized in the same manner. These reagents are useful for testing blood plasma for activation of the coagulation system.
AT79300880T 1978-07-05 1979-05-18 STABILIZED PLATELET FACTOR 4 IMMUNASSAY CALIBRATION SOLUTIONS AND RADIOIMMUNASSAY METHODS. ATE336T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/922,135 US4195072A (en) 1978-07-05 1978-07-05 Stabilized platelet factor 4 immunoassay standards
EP79300880A EP0007163B1 (en) 1978-07-05 1979-05-18 Stabilized platelet factor 4 immunoassay standards and radio-immunoassay method

Publications (1)

Publication Number Publication Date
ATE336T1 true ATE336T1 (en) 1981-11-15

Family

ID=25446555

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79300880T ATE336T1 (en) 1978-07-05 1979-05-18 STABILIZED PLATELET FACTOR 4 IMMUNASSAY CALIBRATION SOLUTIONS AND RADIOIMMUNASSAY METHODS.

Country Status (9)

Country Link
US (1) US4195072A (en)
EP (1) EP0007163B1 (en)
JP (1) JPS5928865B2 (en)
AT (1) ATE336T1 (en)
AU (1) AU525406B2 (en)
CA (1) CA1116078A (en)
DE (1) DE2961056D1 (en)
ES (1) ES482215A1 (en)
ZA (1) ZA792524B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2903701C2 (en) * 1979-01-31 1980-10-16 Boehringer Mannheim Gmbh, 6800 Mannheim Control reagent for the determination of the heparin activity
US4311482A (en) * 1979-10-09 1982-01-19 Abbott Laboratories Method and apparatus for collecting blood samples
DE3019612A1 (en) * 1980-05-22 1981-11-26 Boehringer Mannheim Gmbh, 6800 Mannheim STABILIZED THROMBINE PREPARATION
FR2585836B1 (en) * 1985-08-02 1987-11-27 Commissariat Energie Atomique HOMOGENEOUS METHOD FOR LUMINESCENCE DETECTION AND / OR DETERMINATION OF AN ANALYTE IN A MEDIUM CONTAINING IT
US5166078A (en) * 1986-08-19 1992-11-24 Idexx Laboratories, Inc. Hapten-macromolecule conjugates useful in hapten assays
ES2078264T3 (en) * 1989-06-02 1995-12-16 Abbott Lab STANDARD REAGENTS FOR THE QUANTIFICATION OF HIV P24.
US5599558A (en) * 1989-09-15 1997-02-04 Curative Technologies, Inc. Selecting amounts of platelet releasate for efficacious treatment of tissue
IL95641A0 (en) * 1989-09-15 1991-06-30 Curative Tech Inc Preparation of a platelet releasate product

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3960492A (en) * 1974-05-31 1976-06-01 Nuclear Diagnostics, Inc. Method for determining an index of binding protein content of blood
US4105650A (en) * 1975-04-11 1978-08-08 Edward Shanbrom, Inc. Method of preserving blood plasma i
US3985618A (en) * 1975-05-02 1976-10-12 Irving Innerfield Method for detection of thrombosis and prethrombosis
DE2601372C3 (en) * 1976-01-15 1980-03-27 Behringwerke Ag, 3550 Marburg Method for the determination of antithrombin III
US4097238A (en) * 1977-06-03 1978-06-27 Ashley Sheldon J Method of analyzing blood plasma clotting

Also Published As

Publication number Publication date
EP0007163A1 (en) 1980-01-23
JPS5928865B2 (en) 1984-07-16
AU525406B2 (en) 1982-11-04
ES482215A1 (en) 1980-08-16
JPS5510598A (en) 1980-01-25
DE2961056D1 (en) 1981-12-24
US4195072A (en) 1980-03-25
EP0007163B1 (en) 1981-10-21
AU4738979A (en) 1980-01-31
ZA792524B (en) 1980-06-25
CA1116078A (en) 1982-01-12

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee