ATE335759T1 - Verfahren und zusammensetzungen für die diagnose und die behandlung von krankheiten, die mit eisenüberschuss oder eisenmangel assoziiert sind. - Google Patents

Verfahren und zusammensetzungen für die diagnose und die behandlung von krankheiten, die mit eisenüberschuss oder eisenmangel assoziiert sind.

Info

Publication number
ATE335759T1
ATE335759T1 AT98930243T AT98930243T ATE335759T1 AT E335759 T1 ATE335759 T1 AT E335759T1 AT 98930243 T AT98930243 T AT 98930243T AT 98930243 T AT98930243 T AT 98930243T AT E335759 T1 ATE335759 T1 AT E335759T1
Authority
AT
Austria
Prior art keywords
iron
diagnosis
compositions
treatment
methods
Prior art date
Application number
AT98930243T
Other languages
English (en)
Inventor
John N Feder
Pamela J Bjorkman
Randall C Schatzman
Original Assignee
Bio Rad Laboratories
California Inst Of Techn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Rad Laboratories, California Inst Of Techn filed Critical Bio Rad Laboratories
Application granted granted Critical
Publication of ATE335759T1 publication Critical patent/ATE335759T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT98930243T 1997-06-13 1998-06-12 Verfahren und zusammensetzungen für die diagnose und die behandlung von krankheiten, die mit eisenüberschuss oder eisenmangel assoziiert sind. ATE335759T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87601097A 1997-06-13 1997-06-13

Publications (1)

Publication Number Publication Date
ATE335759T1 true ATE335759T1 (de) 2006-09-15

Family

ID=25366786

Family Applications (2)

Application Number Title Priority Date Filing Date
AT06016507T ATE462717T1 (de) 1997-06-13 1998-06-12 Verfahren und zusammensetzungen für die diagnose und die behandlung von krankheiten, die mit eisenüberschuss oder eisenmangel assoziiert sind
AT98930243T ATE335759T1 (de) 1997-06-13 1998-06-12 Verfahren und zusammensetzungen für die diagnose und die behandlung von krankheiten, die mit eisenüberschuss oder eisenmangel assoziiert sind.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT06016507T ATE462717T1 (de) 1997-06-13 1998-06-12 Verfahren und zusammensetzungen für die diagnose und die behandlung von krankheiten, die mit eisenüberschuss oder eisenmangel assoziiert sind

Country Status (8)

Country Link
US (3) US6391852B1 (de)
EP (2) EP1757614B1 (de)
JP (1) JP2002506438A (de)
AT (2) ATE462717T1 (de)
AU (1) AU745403B2 (de)
CA (1) CA2293808C (de)
DE (2) DE69835519T2 (de)
WO (1) WO1998056814A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140305A (en) 1996-04-04 2000-10-31 Bio-Rad Laboratories, Inc. Hereditary hemochromatosis gene products
US7026116B1 (en) * 1996-04-04 2006-04-11 Bio-Rad Laboratories, Inc. Polymorphisms in the region of the human hemochromatosis gene
US6849399B1 (en) 1996-05-23 2005-02-01 Bio-Rad Laboratories, Inc. Methods and compositions for diagnosis and treatment of iron misregulation diseases
WO1998056814A1 (en) 1997-06-13 1998-12-17 Progenitor, Inc. Methods and compositions for diagnosis and treatment of iron overload diseases and iron deficiency diseases
US6284732B1 (en) 1998-12-18 2001-09-04 Bio-Rad Laboratories, Inc. Peptides and peptide analogues designed from HFE protein and their uses in the treatment of iron overload diseases
US7160855B2 (en) 2002-03-14 2007-01-09 Children's Hospital & Research Center At Oakland Enhancement of iron chelation therapy
ES2674400T3 (es) 2010-02-19 2018-06-29 Dover Chemical Corporation Estabilizadores de polímero de fosfito polimérico líquido libres de alquilfenoles
US9982112B2 (en) 2010-02-19 2018-05-29 Dover Chemical Corporation Copolymeric polyphosphite polymer stabilizers
US8981042B2 (en) 2010-02-19 2015-03-17 Dover Chemical Corporation Cycloaliphatic polyphosphite polymer stabilizers
US9745425B2 (en) 2012-06-22 2017-08-29 Dover Chemical Corporation Cycloaliphatic polyphosphite

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* Cited by examiner, † Cited by third party
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DE208609C (de)
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4434156A (en) 1981-10-26 1984-02-28 The Salk Institute For Biological Studies Monoclonal antibodies specific for the human transferrin receptor glycoprotein
US4511503A (en) 1982-12-22 1985-04-16 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4912118A (en) 1983-09-23 1990-03-27 National Research Development Corporation Pharmaceutical compositions
GB8325494D0 (en) 1983-09-23 1983-10-26 Hider R C Pharmaceutical compositions
US4711845A (en) 1984-08-31 1987-12-08 Cetus Corporation Portable temperature-sensitive control cassette
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
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DE58901673D1 (de) 1988-06-08 1992-07-23 Ciba Geigy Ag Carbamoylierte hydroxamsaeurederivate und verfahren zu ihrer herstellung.
US5116964A (en) 1989-02-23 1992-05-26 Genentech, Inc. Hybrid immunoglobulins
US5582979A (en) 1989-04-21 1996-12-10 Marshfield Clinic Length polymorphisms in (dC-dA)n.(dG-dT)n sequences and method of using the same
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
IL91047A (en) 1989-07-19 1993-06-10 Yissum Res Dev Co Zinc complexes for the treatment of free radical- induced diseases
US5607437A (en) 1990-07-12 1997-03-04 University Of Miami Instruments for use in performing gel injection adjustable keratoplasty
FR2680687A1 (fr) 1991-08-29 1993-03-05 Etienne Marie Christine Compositions pharmaceutiques homeopathiques utilisees pour la fabrication de medicaments destines au traitement des maladies causees par des erreurs metaboliques et au traitement des maladies virales.
EP0570588B1 (de) 1991-12-02 1998-09-09 Oriental Yeast Co., Ltd. Verfahren und Reagenz zur Bestimmung von Serumeisen oder von der Bindungsfähigkeit des ungesättigten Eisens durch Verwendung von Akonitase
GB9209078D0 (en) 1992-04-27 1992-06-10 Hider Robert C Pharmaceutical compositions
CA2139862C (en) 1992-07-10 2007-06-26 Wilfred A. Jefferies Use of p97 and iron binding proteins as diagnostic and therapeutic agents
AU5602594A (en) 1992-11-16 1994-06-08 University Of Florida Research Foundation, Inc. 2-(pyrid-2'-yl)-2-thiazoline-4(s)-carboxylic acid derivatives
US5385918A (en) 1993-02-09 1995-01-31 Miles Inc. Aminomethylene-peptides as immunosuppressants
EP0610745A3 (en) 1993-02-09 1994-09-28 Miles Inc Novel aminomethylene derivatives as immunosuppressants.
ES2124327T3 (es) 1993-02-09 1999-02-01 Bayer Ag Derivados de sulfonamida aminometileno como inmunosupresores.
AU3920293A (en) 1993-03-16 1994-10-11 Board Of Regents Of The University Of Nebraska, The Novel metal binding agents, and methods and compositions for their use to treat metal toxicity
JP3585180B2 (ja) 1993-05-11 2004-11-04 三菱化学株式会社 新規なヒトタンパク質およびそれをコードする遺伝子
DE4327226A1 (de) 1993-08-13 1995-02-16 Hoechst Ag Chelatoren, ihre Herstellung aus den Antibiotika Salmycin A, B oder C und deren Verwendung
HUT74457A (en) 1993-12-16 1996-12-30 Ciba Geigy Ag N,n`-bis(2-hydroxybenzyl)ethylenediamine-n,n`-diacetic acid derivatives, process for preparing them and pharmaceutical compns. contg. them
KR0136993B1 (ko) 1994-09-13 1998-04-24 김주용 비휘발성 메모리 소자 제조방법
US5674681A (en) 1994-12-06 1997-10-07 Rothenberg; Barry E. Methods to identify hemochromatosis
US5753438A (en) 1995-05-08 1998-05-19 Mercator Genetics, Inc. Method to diagnose hereditary hemochromatosis
US5705343A (en) 1995-05-08 1998-01-06 Mercator Genetics, Inc. Method to diagnose hereditary hemochromatosis
US6140305A (en) * 1996-04-04 2000-10-31 Bio-Rad Laboratories, Inc. Hereditary hemochromatosis gene products
US5872237A (en) 1996-04-04 1999-02-16 Mercator Genetics, Inc. Megabase transcript map: novel sequences and antibodies thereto
US6025130A (en) 1996-04-04 2000-02-15 Mercator Genetics, Inc. Hereditary hemochromatosis gene
US5712098A (en) 1996-04-04 1998-01-27 Mercator Genetics Hereditary hemochromatosis diagnostic markers and diagnostic methods
US6849399B1 (en) 1996-05-23 2005-02-01 Bio-Rad Laboratories, Inc. Methods and compositions for diagnosis and treatment of iron misregulation diseases
WO1998014466A1 (en) 1996-10-01 1998-04-09 Progentior, Inc. Polymorphisms and new genes in the region of the human hemochromatosis gene
WO1998056814A1 (en) 1997-06-13 1998-12-17 Progenitor, Inc. Methods and compositions for diagnosis and treatment of iron overload diseases and iron deficiency diseases
US6284732B1 (en) 1998-12-18 2001-09-04 Bio-Rad Laboratories, Inc. Peptides and peptide analogues designed from HFE protein and their uses in the treatment of iron overload diseases

Also Published As

Publication number Publication date
WO1998056814A1 (en) 1998-12-17
EP0988316B1 (de) 2006-08-09
US7374892B2 (en) 2008-05-20
US7119170B2 (en) 2006-10-10
AU745403B2 (en) 2002-03-21
EP0988316A4 (de) 2003-07-09
US20030073627A1 (en) 2003-04-17
EP1757614B1 (de) 2010-03-31
DE69835519D1 (de) 2006-09-21
US20060287236A1 (en) 2006-12-21
EP0988316A1 (de) 2000-03-29
US6391852B1 (en) 2002-05-21
CA2293808C (en) 2006-10-17
CA2293808A1 (en) 1998-12-17
DE69835519T2 (de) 2007-04-05
JP2002506438A (ja) 2002-02-26
EP1757614A1 (de) 2007-02-28
ATE462717T1 (de) 2010-04-15
AU7968198A (en) 1998-12-30
DE69841593D1 (de) 2010-05-12

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