ATE33381T1 - Verfahren zur herstellung von alphahydroxyarylalkans|uren. - Google Patents
Verfahren zur herstellung von alphahydroxyarylalkans|uren.Info
- Publication number
- ATE33381T1 ATE33381T1 AT85100831T AT85100831T ATE33381T1 AT E33381 T1 ATE33381 T1 AT E33381T1 AT 85100831 T AT85100831 T AT 85100831T AT 85100831 T AT85100831 T AT 85100831T AT E33381 T1 ATE33381 T1 AT E33381T1
- Authority
- AT
- Austria
- Prior art keywords
- preparation
- alphahydroxyarylalkans
- ures
- formulawhich
- formulawherein
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 238000005904 alkaline hydrolysis reaction Methods 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 150000004707 phenolate Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000008707 rearrangement Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/30—Compounds having groups
- C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT19438/84A IT1173216B (it) | 1984-02-03 | 1984-02-03 | Processo per la preparazione di acidi alfa-idrossiaril-alcanoici |
| EP85100831A EP0152003B1 (de) | 1984-02-03 | 1985-01-28 | Verfahren zur Herstellung von alpha-Hydroxyarylalkansäuren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE33381T1 true ATE33381T1 (de) | 1988-04-15 |
Family
ID=11157969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85100831T ATE33381T1 (de) | 1984-02-03 | 1985-01-28 | Verfahren zur herstellung von alphahydroxyarylalkans|uren. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4642376A (de) |
| EP (1) | EP0152003B1 (de) |
| JP (1) | JPH0686404B2 (de) |
| AT (1) | ATE33381T1 (de) |
| DE (1) | DE3562087D1 (de) |
| IT (1) | IT1173216B (de) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3978116A (en) * | 1971-11-04 | 1976-08-31 | Syntex Corporation | 2-naphthyl acetic acid derivatives and compositions and methods thereof |
| IE53333B1 (en) * | 1980-09-11 | 1988-10-26 | Syntex Pharma Int | Process for preparing alpha-aromatic group substituted alkanoic acids or esters thereof |
| IL65629A (en) * | 1981-04-30 | 1987-08-31 | Syntex Pharma Int | Preparation of alpha-arylalkanoic acids and esters and salts thereof |
| US4542237A (en) * | 1981-04-30 | 1985-09-17 | Syntex Pharmaceuticals International Limited | Manufacture of alpha-arylalkanoic acids and precursors |
| FI82680C (fi) * | 1981-12-11 | 1991-04-10 | Syntex Pharma Int | Framstaellning av - arylalkansyror. |
| FI831820L (fi) * | 1982-05-27 | 1983-11-28 | Syntex Pharma Int | Foerfarande foer framstaellning av d-2-(6-metoxi-2-naftyl)-propionsyra och dess farmaceutiskt godtagbara salter samt av nya mellanprodukter anvaenda vid deras framstaellning |
| EP0101124B1 (de) * | 1982-08-06 | 1986-01-29 | ZAMBON S.p.A. | Verfahren zur Herstellung von alpha-Arylalkansäuren |
-
1984
- 1984-02-03 IT IT19438/84A patent/IT1173216B/it active
-
1985
- 1985-01-28 DE DE8585100831T patent/DE3562087D1/de not_active Expired
- 1985-01-28 AT AT85100831T patent/ATE33381T1/de not_active IP Right Cessation
- 1985-01-28 EP EP85100831A patent/EP0152003B1/de not_active Expired
- 1985-02-01 US US06/697,450 patent/US4642376A/en not_active Expired - Lifetime
- 1985-02-04 JP JP60019827A patent/JPH0686404B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0686404B2 (ja) | 1994-11-02 |
| IT8419438A0 (it) | 1984-02-03 |
| EP0152003A1 (de) | 1985-08-21 |
| US4642376A (en) | 1987-02-10 |
| IT1173216B (it) | 1987-06-18 |
| JPS60188339A (ja) | 1985-09-25 |
| EP0152003B1 (de) | 1988-04-06 |
| DE3562087D1 (en) | 1988-05-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee | ||
| RZN | Patent revoked |