ATE323085T1 - Heterozyclische verbindungen mit affinität für den ht1 rezeptor und ihre therapeutische verwendung - Google Patents
Heterozyclische verbindungen mit affinität für den ht1 rezeptor und ihre therapeutische verwendungInfo
- Publication number
- ATE323085T1 ATE323085T1 AT03708113T AT03708113T ATE323085T1 AT E323085 T1 ATE323085 T1 AT E323085T1 AT 03708113 T AT03708113 T AT 03708113T AT 03708113 T AT03708113 T AT 03708113T AT E323085 T1 ATE323085 T1 AT E323085T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- alkyl
- carbon
- hydrogen
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0203804.0A GB0203804D0 (en) | 2002-02-18 | 2002-02-18 | Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE323085T1 true ATE323085T1 (de) | 2006-04-15 |
Family
ID=9931290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03708113T ATE323085T1 (de) | 2002-02-18 | 2003-02-17 | Heterozyclische verbindungen mit affinität für den ht1 rezeptor und ihre therapeutische verwendung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7244726B2 (de) |
| EP (1) | EP1476444B1 (de) |
| JP (1) | JP2005527500A (de) |
| AT (1) | ATE323085T1 (de) |
| AU (1) | AU2003212254A1 (de) |
| DE (1) | DE60304559T2 (de) |
| ES (1) | ES2259759T3 (de) |
| GB (1) | GB0203804D0 (de) |
| WO (1) | WO2003068772A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0227240D0 (en) * | 2002-11-21 | 2002-12-31 | Glaxo Group Ltd | Compounds |
| GB0310851D0 (en) * | 2003-05-12 | 2003-06-18 | Glaxo Group Ltd | Compounds |
| GB0316915D0 (en) | 2003-07-18 | 2003-08-20 | Glaxo Group Ltd | Compounds |
| KR100843053B1 (ko) * | 2004-01-16 | 2008-07-01 | 에프. 호프만-라 로슈 아게 | 중추 신경계 질환의 치료를 위한 5-하이드록시트립트아민수용체(5-ｈｔ)의 조절제로서1-벤질-5-피페라진-1-일-3,4-다이하이드로-1ｈ-퀴나졸린-2-온 유도체 및 각각의1ｈ-벤조(1,2,6)티아다이아진-2,2-다이옥사이드 및1,4-다이하이드로-벤조(ｄ)(1,3)옥사진-2-온 유도체 |
| DE102004010132A1 (de) * | 2004-02-27 | 2005-09-15 | Merck Patent Gmbh | Piperidinderivate |
| PL2010120T5 (pl) * | 2006-04-25 | 2015-12-31 | Essity Hygiene & Health Ab | Wyrób chłonny typu majtek i sposoby jego wytwarzania |
| EP3233799B1 (de) | 2014-12-19 | 2021-05-19 | The Broad Institute, Inc. | Dopamin-d2-rezeptor-liganden |
| EP3233077A4 (de) | 2014-12-19 | 2018-08-08 | The Broad Institute Inc. | Dopamin-d2-rezeptor-liganden |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9407447D0 (en) | 1994-04-14 | 1994-06-08 | Glaxo Group Ltd | Chemical compounds |
| ES2191180T3 (es) * | 1996-05-29 | 2003-09-01 | Warner Lambert Co | Antagonistas de los receptores de la dopamina benzoxazinona d4. |
| EP0900792B1 (de) * | 1997-09-02 | 2003-10-29 | Duphar International Research B.V | Piperidin- und Piperazin Derivate als 5-HT1-Rezeptor-Agonisten |
| JP2002510682A (ja) * | 1998-04-08 | 2002-04-09 | アメリカン・ホーム・プロダクツ・コーポレイション | うつ病治療用のインドール−３−イル−シクロヘキシルアミン誘導体（５−ｈｔ１受容体拮抗薬） |
| AU2494300A (en) | 1999-01-07 | 2000-07-24 | American Home Products Corporation | 3,4-dihydro-2h-benzo(1,4)oxazine derivatives |
| PL366378A1 (en) * | 2000-10-26 | 2005-01-24 | Smithkline Beecham P.L.C. | Benzoxazinone derivatives, their preparation and use |
-
2002
- 2002-02-18 GB GBGB0203804.0A patent/GB0203804D0/en not_active Ceased
-
2003
- 2003-02-17 EP EP03708113A patent/EP1476444B1/de not_active Expired - Lifetime
- 2003-02-17 AT AT03708113T patent/ATE323085T1/de not_active IP Right Cessation
- 2003-02-17 US US10/504,109 patent/US7244726B2/en not_active Expired - Fee Related
- 2003-02-17 AU AU2003212254A patent/AU2003212254A1/en not_active Abandoned
- 2003-02-17 JP JP2003567899A patent/JP2005527500A/ja not_active Withdrawn
- 2003-02-17 DE DE60304559T patent/DE60304559T2/de not_active Expired - Fee Related
- 2003-02-17 ES ES03708113T patent/ES2259759T3/es not_active Expired - Lifetime
- 2003-02-17 WO PCT/EP2003/001711 patent/WO2003068772A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| DE60304559D1 (de) | 2006-05-24 |
| AU2003212254A1 (en) | 2003-09-04 |
| ES2259759T3 (es) | 2006-10-16 |
| JP2005527500A (ja) | 2005-09-15 |
| US7244726B2 (en) | 2007-07-17 |
| DE60304559T2 (de) | 2007-04-05 |
| EP1476444B1 (de) | 2006-04-12 |
| EP1476444A1 (de) | 2004-11-17 |
| GB0203804D0 (en) | 2002-04-03 |
| WO2003068772A1 (en) | 2003-08-21 |
| US20050085458A1 (en) | 2005-04-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |