ATE322018T1 - Identifizierung von modulatoren des neurotransmitters xanthurensäure - Google Patents
Identifizierung von modulatoren des neurotransmitters xanthurensäureInfo
- Publication number
- ATE322018T1 ATE322018T1 AT02767548T AT02767548T ATE322018T1 AT E322018 T1 ATE322018 T1 AT E322018T1 AT 02767548 T AT02767548 T AT 02767548T AT 02767548 T AT02767548 T AT 02767548T AT E322018 T1 ATE322018 T1 AT E322018T1
- Authority
- AT
- Austria
- Prior art keywords
- identification
- novel
- targets
- selection
- xanthurenic acid
- Prior art date
Links
- FBZONXHGGPHHIY-UHFFFAOYSA-N xanthurenic acid Chemical compound C1=CC=C(O)C2=NC(C(=O)O)=CC(O)=C21 FBZONXHGGPHHIY-UHFFFAOYSA-N 0.000 title abstract 4
- 239000002858 neurotransmitter agent Substances 0.000 title 1
- 230000008901 benefit Effects 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002452 interceptive effect Effects 0.000 abstract 1
- 230000007246 mechanism Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 230000003340 mental effect Effects 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 239000002831 pharmacologic agent Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 230000002463 transducing effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9406—Neurotransmitters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Psychiatry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0108937A FR2827045B1 (fr) | 2001-07-05 | 2001-07-05 | Methodes et compositions pour la selection et le developpement de nouveaux agents pharmacologiques ou de nouveaux medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE322018T1 true ATE322018T1 (de) | 2006-04-15 |
Family
ID=8865168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02767548T ATE322018T1 (de) | 2001-07-05 | 2002-07-04 | Identifizierung von modulatoren des neurotransmitters xanthurensäure |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7122326B2 (de) |
| EP (1) | EP1402270B1 (de) |
| JP (1) | JP4230352B2 (de) |
| AT (1) | ATE322018T1 (de) |
| CA (1) | CA2451092A1 (de) |
| CY (1) | CY1105291T1 (de) |
| DE (1) | DE60210309T2 (de) |
| DK (1) | DK1402270T3 (de) |
| ES (1) | ES2260477T3 (de) |
| FR (1) | FR2827045B1 (de) |
| PT (1) | PT1402270E (de) |
| WO (1) | WO2003005038A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002950217A0 (en) * | 2002-07-16 | 2002-09-12 | Prana Biotechnology Limited | 8- Hydroxy Quinoline Derivatives |
| US8697674B2 (en) * | 2004-12-29 | 2014-04-15 | Naturon, Inc. | Xanthurenic acid derivative pharmaceutical compositions and methods related thereto |
| EP2146209B1 (de) * | 2005-04-06 | 2011-11-16 | University of Antwerp | Neurodegenerative Marker für Alzheimer-Krankheit |
| WO2008108994A1 (en) * | 2007-03-01 | 2008-09-12 | Carnegie Institution Of Washington | Trp/his exchange and kynurenine induced trp transport |
| CN101945663B (zh) * | 2008-02-15 | 2013-12-04 | 株式会社津村 | 抑肝散的生物测定方法 |
| WO2009157083A1 (ja) * | 2008-06-27 | 2009-12-30 | 株式会社ツムラ | 抑肝散のバイオアッセイ方法 |
| JP2014016366A (ja) * | 2013-10-02 | 2014-01-30 | Tsumura & Co | 抑肝散のバイオアッセイ方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1265101B1 (it) * | 1993-07-23 | 1996-10-30 | Erba Carlo Spa | Derivati dell'acido 2-ammino-4-fenil-4-osso butirrico |
| GB9614823D0 (en) * | 1996-07-15 | 1996-09-04 | Pharmacia Spa | Recombinant kynurenine-3-hydroxylase enzyme and process for its preparation |
| AU7389098A (en) * | 1997-05-16 | 1998-12-08 | Brigham And Women's Hospital | Local anesthetic formulations |
| EP1188056A1 (de) * | 1999-06-01 | 2002-03-20 | Merck Frosst Canada & Co. | Die verwendung von gabapentin in tests zur bestimmung von gabab rezeptor-modulatoren |
-
2001
- 2001-07-05 FR FR0108937A patent/FR2827045B1/fr not_active Expired - Fee Related
-
2002
- 2002-07-04 PT PT02767548T patent/PT1402270E/pt unknown
- 2002-07-04 DK DK02767548T patent/DK1402270T3/da active
- 2002-07-04 WO PCT/FR2002/002337 patent/WO2003005038A1/fr not_active Ceased
- 2002-07-04 AT AT02767548T patent/ATE322018T1/de not_active IP Right Cessation
- 2002-07-04 CA CA002451092A patent/CA2451092A1/fr not_active Abandoned
- 2002-07-04 US US10/481,595 patent/US7122326B2/en not_active Expired - Fee Related
- 2002-07-04 EP EP02767548A patent/EP1402270B1/de not_active Expired - Lifetime
- 2002-07-04 DE DE60210309T patent/DE60210309T2/de not_active Expired - Fee Related
- 2002-07-04 ES ES02767548T patent/ES2260477T3/es not_active Expired - Lifetime
- 2002-07-04 JP JP2003510963A patent/JP4230352B2/ja not_active Expired - Fee Related
-
2006
- 2006-06-21 CY CY20061100830T patent/CY1105291T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004533843A (ja) | 2004-11-11 |
| WO2003005038A1 (fr) | 2003-01-16 |
| JP4230352B2 (ja) | 2009-02-25 |
| US20040157917A1 (en) | 2004-08-12 |
| DK1402270T3 (da) | 2006-07-24 |
| CY1105291T1 (el) | 2010-03-03 |
| EP1402270B1 (de) | 2006-03-29 |
| ES2260477T3 (es) | 2006-11-01 |
| PT1402270E (pt) | 2006-08-31 |
| CA2451092A1 (fr) | 2003-01-16 |
| EP1402270A1 (de) | 2004-03-31 |
| DE60210309T2 (de) | 2006-11-09 |
| FR2827045B1 (fr) | 2007-08-10 |
| DE60210309D1 (de) | 2006-05-18 |
| US7122326B2 (en) | 2006-10-17 |
| FR2827045A1 (fr) | 2003-01-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1402270 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |