ATE318263T1 - Hydroxamsäure-derivate - Google Patents
Hydroxamsäure-derivateInfo
- Publication number
- ATE318263T1 ATE318263T1 AT02747621T AT02747621T ATE318263T1 AT E318263 T1 ATE318263 T1 AT E318263T1 AT 02747621 T AT02747621 T AT 02747621T AT 02747621 T AT02747621 T AT 02747621T AT E318263 T1 ATE318263 T1 AT E318263T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- sup
- compounds
- acid derivatives
- hydroxamic acid
- Prior art date
Links
- NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 208000006820 Arthralgia Diseases 0.000 abstract 1
- 229940124761 MMP inhibitor Drugs 0.000 abstract 1
- 208000000491 Tendinopathy Diseases 0.000 abstract 1
- 206010043255 Tendonitis Diseases 0.000 abstract 1
- 238000010171 animal model Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 201000004415 tendinitis Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/96—Sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0119396.0A GB0119396D0 (en) | 2001-08-09 | 2001-08-09 | Hydroxamic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE318263T1 true ATE318263T1 (de) | 2006-03-15 |
Family
ID=9920067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02747621T ATE318263T1 (de) | 2001-08-09 | 2002-08-07 | Hydroxamsäure-derivate |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7015234B2 (de) |
| EP (1) | EP1414812B1 (de) |
| JP (1) | JP2005501090A (de) |
| KR (1) | KR20040035725A (de) |
| CN (1) | CN1275954C (de) |
| AT (1) | ATE318263T1 (de) |
| BR (1) | BR0211780A (de) |
| CA (1) | CA2456291A1 (de) |
| DE (1) | DE60209354T2 (de) |
| EA (1) | EA006877B1 (de) |
| ES (1) | ES2257561T3 (de) |
| GB (1) | GB0119396D0 (de) |
| HU (1) | HUP0401187A2 (de) |
| IL (1) | IL160266A0 (de) |
| MX (1) | MXPA04001212A (de) |
| NO (1) | NO20040551L (de) |
| NZ (1) | NZ531521A (de) |
| PL (1) | PL368228A1 (de) |
| PT (1) | PT1414812E (de) |
| WO (1) | WO2003014101A1 (de) |
| ZA (1) | ZA200401873B (de) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166452A (en) * | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4256108A (en) * | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) * | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| KR100609926B1 (ko) * | 1997-11-12 | 2006-08-04 | 다윈 디스커버리 리미티드 | 엠엠피와 티엔에프 억제 활성을 갖는 히드록삼산 및카르복실산 유도체 |
| US6187924B1 (en) * | 1997-11-12 | 2001-02-13 | Darwin Discovery, Ltd. | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity |
| AP2001002240A0 (en) * | 1999-02-08 | 2001-09-30 | Searle & Co | Sufamato hydroxamic acid metalloprotease inhibitor. |
-
2001
- 2001-08-09 GB GBGB0119396.0A patent/GB0119396D0/en not_active Ceased
-
2002
- 2002-08-07 PL PL02368228A patent/PL368228A1/xx not_active Application Discontinuation
- 2002-08-07 MX MXPA04001212A patent/MXPA04001212A/es unknown
- 2002-08-07 EP EP02747621A patent/EP1414812B1/de not_active Expired - Lifetime
- 2002-08-07 CA CA002456291A patent/CA2456291A1/en not_active Abandoned
- 2002-08-07 HU HU0401187A patent/HUP0401187A2/hu unknown
- 2002-08-07 AT AT02747621T patent/ATE318263T1/de not_active IP Right Cessation
- 2002-08-07 ES ES02747621T patent/ES2257561T3/es not_active Expired - Lifetime
- 2002-08-07 NZ NZ531521A patent/NZ531521A/en unknown
- 2002-08-07 DE DE60209354T patent/DE60209354T2/de not_active Expired - Fee Related
- 2002-08-07 PT PT02747621T patent/PT1414812E/pt unknown
- 2002-08-07 WO PCT/GB2002/003656 patent/WO2003014101A1/en not_active Ceased
- 2002-08-07 JP JP2003519051A patent/JP2005501090A/ja active Pending
- 2002-08-07 EA EA200400287A patent/EA006877B1/ru unknown
- 2002-08-07 US US10/485,905 patent/US7015234B2/en not_active Expired - Fee Related
- 2002-08-07 KR KR10-2004-7001959A patent/KR20040035725A/ko not_active Withdrawn
- 2002-08-07 CN CNB028200225A patent/CN1275954C/zh not_active Expired - Fee Related
- 2002-08-07 IL IL16026602A patent/IL160266A0/xx unknown
- 2002-08-07 BR BR0211780-0A patent/BR0211780A/pt not_active IP Right Cessation
-
2004
- 2004-02-06 NO NO20040551A patent/NO20040551L/no not_active Application Discontinuation
- 2004-03-08 ZA ZA200401873A patent/ZA200401873B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20040192733A1 (en) | 2004-09-30 |
| HUP0401187A2 (hu) | 2004-12-28 |
| PL368228A1 (en) | 2005-03-21 |
| NZ531521A (en) | 2005-06-24 |
| ES2257561T3 (es) | 2006-08-01 |
| PT1414812E (pt) | 2006-05-31 |
| US7015234B2 (en) | 2006-03-21 |
| KR20040035725A (ko) | 2004-04-29 |
| EP1414812B1 (de) | 2006-02-22 |
| ZA200401873B (en) | 2005-03-08 |
| MXPA04001212A (es) | 2004-07-08 |
| JP2005501090A (ja) | 2005-01-13 |
| IL160266A0 (en) | 2004-07-25 |
| EA006877B1 (ru) | 2006-04-28 |
| CN1275954C (zh) | 2006-09-20 |
| EA200400287A1 (ru) | 2004-06-24 |
| CA2456291A1 (en) | 2003-02-20 |
| DE60209354T2 (de) | 2006-10-19 |
| NO20040551L (no) | 2004-05-10 |
| BR0211780A (pt) | 2004-07-27 |
| CN1568320A (zh) | 2005-01-19 |
| EP1414812A1 (de) | 2004-05-06 |
| DE60209354D1 (de) | 2006-04-27 |
| GB0119396D0 (en) | 2001-10-03 |
| WO2003014101A1 (en) | 2003-02-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1414812 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |