ATE317427T1 - Anwendung von monocyte-abstammende zellen, antigene und antikörper zur optimalen induzierung einer immuntherapeutischen leistungsfähigkeit - Google Patents

Anwendung von monocyte-abstammende zellen, antigene und antikörper zur optimalen induzierung einer immuntherapeutischen leistungsfähigkeit

Info

Publication number
ATE317427T1
ATE317427T1 AT99917887T AT99917887T ATE317427T1 AT E317427 T1 ATE317427 T1 AT E317427T1 AT 99917887 T AT99917887 T AT 99917887T AT 99917887 T AT99917887 T AT 99917887T AT E317427 T1 ATE317427 T1 AT E317427T1
Authority
AT
Austria
Prior art keywords
tumor
antigens
antigen
derived cells
monocyte
Prior art date
Application number
AT99917887T
Other languages
English (en)
Inventor
Jacques Bartholeyns
Yves Fouron
Jean-Loup Romet-Lemonne
Original Assignee
Idm Immuno Designed Molecules
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idm Immuno Designed Molecules filed Critical Idm Immuno Designed Molecules
Application granted granted Critical
Publication of ATE317427T1 publication Critical patent/ATE317427T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0645—Macrophages, e.g. Kuepfer cells in the liver; Monocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4614—Monocytes; Macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6056—Antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/622—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier non-covalent binding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AT99917887T 1998-04-09 1999-03-29 Anwendung von monocyte-abstammende zellen, antigene und antikörper zur optimalen induzierung einer immuntherapeutischen leistungsfähigkeit ATE317427T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98400883 1998-04-09

Publications (1)

Publication Number Publication Date
ATE317427T1 true ATE317427T1 (de) 2006-02-15

Family

ID=8235338

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99917887T ATE317427T1 (de) 1998-04-09 1999-03-29 Anwendung von monocyte-abstammende zellen, antigene und antikörper zur optimalen induzierung einer immuntherapeutischen leistungsfähigkeit

Country Status (9)

Country Link
US (1) US20020168347A1 (de)
EP (1) EP1068297B1 (de)
JP (1) JP2002511247A (de)
AT (1) ATE317427T1 (de)
AU (1) AU769621B2 (de)
CA (1) CA2321181A1 (de)
DE (1) DE69929781T2 (de)
ES (1) ES2255259T3 (de)
WO (1) WO1999053026A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7638122B2 (en) * 2003-03-07 2009-12-29 University Of South Florida Stat3 antagonists and their use as vaccines against cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8800981A1 (es) * 1985-06-28 1987-12-01 Univ Minnesota Un procedimiento para tratar celulas efectoras que tienen receptores de superficie para la region fc de un anticuerpo
JP3360108B2 (ja) * 1989-10-20 2002-12-24 メダレックス インク． 二つのエフェクター機能を有する二元特異性異種抗体
WO1992005793A1 (en) * 1990-10-05 1992-04-16 Medarex, Inc. Targeted immunostimulation with bispecific reagents
DE9390311U1 (de) * 1993-05-18 1996-05-09 Idm Immuno Designed Molecules Neue Makrophagen mit Eignung als Wirkstoffe von pharmazeutischen Zusammensetzungen
FR2729570A1 (fr) * 1995-01-24 1996-07-26 Idm Immuno Designed Molecules Procede de preparation de macrophages actives, trousses et compositions pour la mise en oeuvre de ce procede
US5985270A (en) * 1995-09-13 1999-11-16 Fordham University Adoptive immunotherapy using macrophages sensitized with heat shock protein-epitope complexes
EP0808897A1 (de) * 1996-05-21 1997-11-26 I.D.M. Immuno-Designed Molecules Antigenpräsentierende Zellen, ein Verfahren zur deren Herstellung und deren Verwendung als zelluläre Impfstoffen

Also Published As

Publication number Publication date
DE69929781D1 (de) 2006-04-20
AU3601199A (en) 1999-11-01
WO1999053026A1 (en) 1999-10-21
DE69929781T2 (de) 2006-10-05
US20020168347A1 (en) 2002-11-14
AU769621B2 (en) 2004-01-29
EP1068297B1 (de) 2006-02-08
ES2255259T3 (es) 2006-06-16
EP1068297A1 (de) 2001-01-17
CA2321181A1 (en) 1999-10-21
JP2002511247A (ja) 2002-04-16

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