ATE307207T1 - Ein kombiniertes antigen vom menschlichen cytomegalievirus und seine anwendung - Google Patents

Ein kombiniertes antigen vom menschlichen cytomegalievirus und seine anwendung

Info

Publication number
ATE307207T1
ATE307207T1 AT97905078T AT97905078T ATE307207T1 AT E307207 T1 ATE307207 T1 AT E307207T1 AT 97905078 T AT97905078 T AT 97905078T AT 97905078 T AT97905078 T AT 97905078T AT E307207 T1 ATE307207 T1 AT E307207T1
Authority
AT
Austria
Prior art keywords
human cytomegalovirus
hcmv
application
combined antigen
specific antibodies
Prior art date
Application number
AT97905078T
Other languages
English (en)
Inventor
Catharina Anna Bruggeman
Cornelis Vink
Frans Stals
Albert Ramon
Original Assignee
Univ Maastricht
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Maastricht filed Critical Univ Maastricht
Application granted granted Critical
Publication of ATE307207T1 publication Critical patent/ATE307207T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT97905078T 1996-02-22 1997-02-20 Ein kombiniertes antigen vom menschlichen cytomegalievirus und seine anwendung ATE307207T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/605,541 US5800981A (en) 1996-02-22 1996-02-22 Human cytomegalovirus antigen and its use
PCT/EP1997/000865 WO1997031117A2 (en) 1996-02-22 1997-02-20 A human cytomegalovirus combined antigen and its use

Publications (1)

Publication Number Publication Date
ATE307207T1 true ATE307207T1 (de) 2005-11-15

Family

ID=24424094

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97905078T ATE307207T1 (de) 1996-02-22 1997-02-20 Ein kombiniertes antigen vom menschlichen cytomegalievirus und seine anwendung

Country Status (9)

Country Link
US (1) US5800981A (de)
EP (1) EP0882132B1 (de)
JP (1) JP2001517072A (de)
AT (1) ATE307207T1 (de)
AU (1) AU732254B2 (de)
DE (1) DE69734387T2 (de)
DK (1) DK0882132T3 (de)
ES (1) ES2251016T3 (de)
WO (1) WO1997031117A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757169B1 (fr) * 1996-12-13 1999-03-05 Inst Nat Sante Rech Med Proteine de fusion comportant tout ou partie de la proteine pp65 de cmv humain, utile notamment dans la preparation d'un vaccin
DE19910044A1 (de) * 1999-03-08 2000-09-14 Bodo Plachter Virale Partikel, die nach Infektion durch humanes Cytomegalovirus freigesetzt werden und ihre Verwendung als Impfstoff
EP1057895A1 (de) * 1999-06-04 2000-12-06 Lohmann Animal Health GmbH & Co. KG Fusionsprotein das das Fragment B des Shigatoxins enthält, dieses enthaltende (Impf-)Stoffzusammensetzung und Verfahren zu dessen Herstellung
US6569616B1 (en) 1999-07-29 2003-05-27 Wisconsin Alumni Research Foundation Human cytomegalovirus glycoprotein O as a new drug target and subunit vaccine candidate
RU2218408C2 (ru) * 2001-11-05 2003-12-10 Государственный научный центр вирусологии и биотехнологии "Вектор" РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pUL83HCMV, ОБЕСПЕЧИВАЮЩАЯ ЭКСПРЕССИЮ В КЛЕТКАХ БАКТЕРИИ Escherichia coli РЕКОМБИНАНТНОГО БЕЛКА, СОДЕРЖАЩЕГО ИММУНОДОМИНАНТНУЮ ЧАСТЬ ФОСФОПРОТЕИНА pp65 HCMV И ФРАГМЕНТ β-ГАЛАКТОЗИДАЗЫ
DE60333035D1 (de) * 2002-12-23 2010-07-29 Vical Inc Impfstoffe gegen infektionen mit dem humanen zytomegalivirus auf grundlage von codonoptimierten polynukleotiden
US20040228842A1 (en) * 2003-02-27 2004-11-18 Shan Lu Compositions and methods for cytomegalovirus treatment
WO2007036056A1 (en) * 2005-09-27 2007-04-05 Oncalis Ag Genetic selection system to identify proteases, protease substrates and protease inhibitors
US7947274B2 (en) 2007-01-04 2011-05-24 Humabs, LLC. Human cytomegalovirus neutralising antibodies and use thereof
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
BRPI0916443A2 (pt) 2008-07-16 2017-10-31 Inst Res Biomedicine anticorpos de neutralização de citomegalovírus humanos e uso dos mesmos
NZ600974A (en) 2009-12-23 2014-08-29 4Antibody Ag Binding members for human cytomegalovirus
US10611800B2 (en) 2016-03-11 2020-04-07 Pfizer Inc. Human cytomegalovirus gB polypeptide
US11629172B2 (en) 2018-12-21 2023-04-18 Pfizer Inc. Human cytomegalovirus gB polypeptide
TWI810589B (zh) 2020-06-21 2023-08-01 美商輝瑞股份有限公司 人巨細胞病毒糖蛋白Ｂ（ｇＢ）多肽

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1266740B1 (it) * 1994-07-01 1997-01-14 Maria Paola Landini Materiale proteico ricombinante legante anticorpi contro il citomegalovirus umano, reagenti diagnostici derivati da tale
DE4426453C1 (de) * 1994-07-26 1995-11-02 Biotest Ag Rekombinant hergestellte Fusionsproteine des Cytomegalievirus und diese enthaltende diagnostische Testkits

Also Published As

Publication number Publication date
AU732254B2 (en) 2001-04-12
DK0882132T3 (da) 2006-03-06
DE69734387D1 (de) 2006-03-02
JP2001517072A (ja) 2001-10-02
ES2251016T3 (es) 2006-04-16
AU1876397A (en) 1997-09-10
WO1997031117A2 (en) 1997-08-28
EP0882132B1 (de) 2005-10-19
DE69734387T2 (de) 2006-07-06
US5800981A (en) 1998-09-01
WO1997031117A3 (en) 1997-10-02
EP0882132A2 (de) 1998-12-09

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