ATE299703T1 - Mmp-hemmer bei bindegewebserweichung - Google Patents

Mmp-hemmer bei bindegewebserweichung

Info

Publication number
ATE299703T1
ATE299703T1 AT00903808T AT00903808T ATE299703T1 AT E299703 T1 ATE299703 T1 AT E299703T1 AT 00903808 T AT00903808 T AT 00903808T AT 00903808 T AT00903808 T AT 00903808T AT E299703 T1 ATE299703 T1 AT E299703T1
Authority
AT
Austria
Prior art keywords
connective tissue
mmp inhibitors
tissue softening
softening
connective
Prior art date
Application number
AT00903808T
Other languages
English (en)
Inventor
Mark William James Ferguson
Vale Furness
Original Assignee
Renovo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Renovo Ltd filed Critical Renovo Ltd
Application granted granted Critical
Publication of ATE299703T1 publication Critical patent/ATE299703T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Prostheses (AREA)
  • Package Frames And Binding Bands (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT00903808T 1999-02-18 2000-02-14 Mmp-hemmer bei bindegewebserweichung ATE299703T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9903598.2A GB9903598D0 (en) 1999-02-18 1999-02-18 Connective tissue healing
PCT/GB2000/000474 WO2000048617A2 (en) 1999-02-18 2000-02-14 Connective tissue softening

Publications (1)

Publication Number Publication Date
ATE299703T1 true ATE299703T1 (de) 2005-08-15

Family

ID=10847938

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00903808T ATE299703T1 (de) 1999-02-18 2000-02-14 Mmp-hemmer bei bindegewebserweichung

Country Status (12)

Country Link
US (1) US6455569B1 (de)
EP (1) EP1152757B1 (de)
JP (1) JP2002537268A (de)
AT (1) ATE299703T1 (de)
AU (1) AU772470B2 (de)
CA (1) CA2362279C (de)
DE (1) DE60021350T2 (de)
DK (1) DK1152757T3 (de)
ES (1) ES2244410T3 (de)
GB (1) GB9903598D0 (de)
PT (1) PT1152757E (de)
WO (1) WO2000048617A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436629B1 (en) * 2000-10-27 2002-08-20 The Regents Of The University Of California Modulating angiogenesis
WO2004060346A2 (en) 2002-12-30 2004-07-22 Angiotech International Ag Drug delivery from rapid gelling polymer composition
US20070259030A1 (en) * 2006-05-05 2007-11-08 Drapeau Susan J Methods, systems and reagents for tendon and ligament therapy
RU2542471C2 (ru) 2006-11-15 2015-02-20 Коуда Терапьютикс, Инк. Улучшенные способы и композиции для заживления ран
US8323642B2 (en) * 2006-12-13 2012-12-04 Depuy Mitek, Inc. Tissue fusion method using collagenase for repair of soft tissue
EP2234656A2 (de) 2007-12-21 2010-10-06 Coda Therapeutics, Inc. Verbesserte medizinische vorrichtungen
AU2008343840A1 (en) * 2007-12-21 2009-07-09 Coda Therapeutics, Inc. Use of anti-connexin polynucleotides, peptides or antibodies for the treatment of orthopedic conditions
EP2252690A2 (de) * 2007-12-21 2010-11-24 Coda Therapeutics, Inc. Verwendung von anti-connexin-43-polynukleotiden zur behandlung abnormaler oder übermässiger narben
WO2016029191A2 (en) 2014-08-22 2016-02-25 Auckland Uniservices Limited Channel modulators
WO2022128057A1 (en) 2020-12-14 2022-06-23 Symrise Ag Medicament for prevention and treatment of collagen degradation in human connecting tissue
US12667586B2 (en) 2023-03-07 2026-06-30 Glaukos Corporation Treatments for ocular surface disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8827305D0 (en) * 1988-11-23 1988-12-29 British Bio Technology Compounds
US5239078A (en) * 1990-11-21 1993-08-24 Glycomed Incorporated Matrix metalloprotease inhibitors
US5318964A (en) * 1992-06-11 1994-06-07 Hoffmann-La Roche Inc. Hydroxamic derivatives and pharmaceutical compositions
US5310759A (en) 1992-08-12 1994-05-10 Bockman Richard S Methods of protecting and preserving connective and support tissues
CA2160139A1 (en) * 1993-04-07 1994-10-13 Richard Edward Galardy Synthetic matrix metalloprotease inhibitors and uses thereof
GB9405076D0 (en) 1994-03-16 1994-04-27 Inst Of Ophtalmology A medical use of matrix metalloproteinase inhibitors
DE19542189A1 (de) 1995-11-13 1997-05-15 Hoechst Ag Cyclische N-substituierte alpha-Iminohydroxamsäuren
TR199800849T2 (xx) * 1995-11-13 1998-07-21 Hoechst Aktiengesellschaft Siklikle heterosiklik N-ikame edilmi� alfa-iminohidroksamla karbon asitleri
GB9714936D0 (en) * 1997-07-17 1997-09-17 Smith & Nephew Cell culture products

Also Published As

Publication number Publication date
WO2000048617A3 (en) 2001-02-08
ES2244410T3 (es) 2005-12-16
PT1152757E (pt) 2005-09-30
CA2362279C (en) 2010-05-25
CA2362279A1 (en) 2000-08-24
DE60021350D1 (de) 2005-08-25
AU2557100A (en) 2000-09-04
US6455569B1 (en) 2002-09-24
JP2002537268A (ja) 2002-11-05
HK1037960A1 (en) 2002-03-01
DK1152757T3 (da) 2005-10-31
DE60021350T2 (de) 2006-04-27
AU772470B2 (en) 2004-04-29
WO2000048617A2 (en) 2000-08-24
EP1152757A2 (de) 2001-11-14
EP1152757B1 (de) 2005-07-20
GB9903598D0 (en) 1999-04-07

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