ATE290221T1 - Verfahren zur herstellung eines mr- kontrastmittels - Google Patents
Verfahren zur herstellung eines mr- kontrastmittelsInfo
- Publication number
- ATE290221T1 ATE290221T1 AT00929722T AT00929722T ATE290221T1 AT E290221 T1 ATE290221 T1 AT E290221T1 AT 00929722 T AT00929722 T AT 00929722T AT 00929722 T AT00929722 T AT 00929722T AT E290221 T1 ATE290221 T1 AT E290221T1
- Authority
- AT
- Austria
- Prior art keywords
- chamber
- hydrogenation
- inlet
- liquid
- solvent removal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1806—Suspensions, emulsions, colloids, dispersions
- A61K49/1815—Suspensions, emulsions, colloids, dispersions compo-inhalant, e.g. breath tests
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
- Glass Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9911681.6A GB9911681D0 (en) | 1999-05-19 | 1999-05-19 | Process |
PCT/GB2000/001897 WO2000071166A2 (en) | 1999-05-19 | 2000-05-17 | Process |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE290221T1 true ATE290221T1 (de) | 2005-03-15 |
Family
ID=10853772
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00929722T ATE290221T1 (de) | 1999-05-19 | 2000-05-17 | Verfahren zur herstellung eines mr- kontrastmittels |
Country Status (12)
Country | Link |
---|---|
US (2) | US6872380B2 (de) |
EP (2) | EP1179189B1 (de) |
JP (1) | JP2003500369A (de) |
KR (1) | KR100786476B1 (de) |
CN (1) | CN1203321C (de) |
AT (1) | ATE290221T1 (de) |
AU (1) | AU775374B2 (de) |
CA (1) | CA2372572C (de) |
DE (1) | DE60018408T2 (de) |
GB (1) | GB9911681D0 (de) |
RU (1) | RU2240828C2 (de) |
WO (1) | WO2000071166A2 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9911679D0 (en) * | 1999-05-19 | 1999-07-21 | Nycomed Imaging As | Magnetic resonance imaging |
US6574496B1 (en) * | 1999-05-19 | 2003-06-03 | Amersham Health As | Magnetic resonance imaging |
GB0219952D0 (en) * | 2002-08-29 | 2002-10-02 | Amersham Health R & D Ab | Method and apparatus for producing contrast agents for magnetic resonance imaging |
GB0219954D0 (en) * | 2002-08-29 | 2002-10-02 | Amersham Health R & D Ab | Method and apparatus for producing contrast agents for magnetic resonance imaging |
GB0219953D0 (en) * | 2002-08-29 | 2002-10-02 | Amersham Health R & D Ab | An arrangement and a method for providing contrast agents |
WO2007044867A2 (en) * | 2005-10-11 | 2007-04-19 | Huntington Medical Research Institutes | Imaging agents and methods of use thereof |
EP1986702A4 (de) * | 2006-02-21 | 2012-12-12 | Avrum Belzer | Hyperpolarisationsverfahren, systeme und zusammensetzungen |
EP2117607A4 (de) * | 2007-01-11 | 2012-08-08 | Huntington Medical Res Inst | Abbildungswirkstoffe und verfahren zu ihrer verwendung |
US20080275668A1 (en) * | 2007-05-02 | 2008-11-06 | General Electric Company | Apparatus and method for fully automated closed system optical measurement of volume |
GB2450316A (en) * | 2007-06-18 | 2008-12-24 | Univ York | Hyperpolarizing nuclei |
US20100233089A1 (en) * | 2007-10-05 | 2010-09-16 | Huntington Medical Research Institutes | Imaging of genetic material with magnetic resonance |
WO2009129265A1 (en) * | 2008-04-14 | 2009-10-22 | Huntington Medical Research Institutes | Methods and apparatus for pasadena hyperpolarization |
PT2349350T (pt) | 2008-10-03 | 2017-01-23 | Bracco Imaging Spa | Um processo para a preparação de soluções aquosas de moléculas hiperpolarizadas |
WO2010067076A2 (en) | 2008-12-10 | 2010-06-17 | University Of York | Pulse sequencing with hyperpolarisable nuclei |
EP2495333A1 (de) * | 2011-03-03 | 2012-09-05 | Roche Diagnostics GmbH | Verfahren zum Herstellen eines Testelements zur Untersuchung einer Körperflüssigkeitsprobe und Testelement |
EP2847591A1 (de) | 2012-05-07 | 2015-03-18 | Albeda Innovation ApS | Intraoperative krebsdiagnose auf basis eines hyperpolarisierten markers |
US9329246B2 (en) * | 2012-10-03 | 2016-05-03 | Bruker Biospin Ag | Method for hyperpolarization transfer in the liquid state |
US9566354B2 (en) | 2012-10-23 | 2017-02-14 | Vanderbilt University | Systems and methods of performing NMR spectroscopy and MRI |
CN103432977B (zh) * | 2013-08-29 | 2015-01-07 | 中国科学院武汉物理与数学研究所 | 一种用于磁共振造影剂预极化的级联容器及其方法 |
ES2745529T3 (es) | 2013-10-28 | 2020-03-02 | Bracco Imaging Spa | Procedimiento para la preparación de compuestos de carboxilato hiperpolarizado |
WO2017009856A1 (en) * | 2015-07-16 | 2017-01-19 | Aspect Imaging Ltd. | Method and system for hyperpolarization of materials used in magnetic resonance imaging |
WO2022266662A1 (en) * | 2021-06-17 | 2022-12-22 | University Of Florida Research Foundation, Inc. | Methods and systems for producing hyperpolarized fluid samples |
EP4141464A1 (de) * | 2021-08-26 | 2023-03-01 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Breitbandverfahren zur signalverstärkung von magnetresonanzkontrastmitteln innerhalb von sekunden und deren reinigung |
WO2023196602A1 (en) * | 2022-04-07 | 2023-10-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Infusion device for the preparation and delivery of mri probes |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1276290A (en) * | 1917-01-06 | 1918-08-20 | Thomas Bailey Walker | Process of and apparatus for hydrogenating fats, oils, waxes, and the like. |
US2134571A (en) * | 1934-07-27 | 1938-10-25 | American Lurgi Corp | Device for the hydrogenation of vegetable or animal oils or fats, fatty acids, or the like |
US4194051A (en) * | 1975-08-25 | 1980-03-18 | Monsanto Company | Asymmetric catalysis |
JPH0721149B2 (ja) * | 1989-12-04 | 1995-03-08 | ユーオーピー | 芳香族炭化水素の連続接触的選択的製造方法 |
DE69300826T2 (de) * | 1993-09-22 | 1996-04-18 | Pfizer Research And Development Co., N.V./S.A., Dublin | Hydrierung. |
IT1283650B1 (it) * | 1996-08-02 | 1998-04-23 | Bracco Spa | Chelati paramagnetici ad alta relassivita' in siero |
WO1998030918A1 (en) * | 1997-01-08 | 1998-07-16 | Nycomed Imaging As | Method of magnetic resonance imaging |
DE19742548C2 (de) * | 1997-09-26 | 1999-10-07 | Otten Ernst Wilhelm | Magneteinrichtung für Tansport und Aufbewahrung kernspinpolarisierter Gase und Verfahren zur Entnahme dieser Gase |
RU2218182C2 (ru) * | 1997-11-12 | 2003-12-10 | Амершем Хелт АС | Агенты, меченные параводородом, и их применение для магнитной резонансной визуализации |
JP2002534687A (ja) * | 1998-12-30 | 2002-10-15 | アメルシャム・パブリック・リミテッド・カンパニー | 過分極を使用したnmr分光学アッセイ |
-
1999
- 1999-05-19 GB GBGB9911681.6A patent/GB9911681D0/en not_active Ceased
-
2000
- 2000-05-17 JP JP2000619467A patent/JP2003500369A/ja active Pending
- 2000-05-17 KR KR1020017014685A patent/KR100786476B1/ko not_active IP Right Cessation
- 2000-05-17 EP EP00929722A patent/EP1179189B1/de not_active Expired - Lifetime
- 2000-05-17 EP EP04027810A patent/EP1548454A1/de not_active Withdrawn
- 2000-05-17 AU AU47723/00A patent/AU775374B2/en not_active Ceased
- 2000-05-17 WO PCT/GB2000/001897 patent/WO2000071166A2/en active IP Right Grant
- 2000-05-17 CA CA002372572A patent/CA2372572C/en not_active Expired - Fee Related
- 2000-05-17 DE DE60018408T patent/DE60018408T2/de not_active Expired - Lifetime
- 2000-05-17 AT AT00929722T patent/ATE290221T1/de not_active IP Right Cessation
- 2000-05-17 CN CNB008077827A patent/CN1203321C/zh not_active Expired - Fee Related
- 2000-05-17 RU RU2001130172/15A patent/RU2240828C2/ru not_active IP Right Cessation
-
2001
- 2001-11-16 US US09/990,537 patent/US6872380B2/en not_active Expired - Lifetime
-
2004
- 2004-12-02 US US11/002,864 patent/US7459144B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1548454A1 (de) | 2005-06-29 |
GB9911681D0 (en) | 1999-07-21 |
EP1179189A2 (de) | 2002-02-13 |
JP2003500369A (ja) | 2003-01-07 |
US6872380B2 (en) | 2005-03-29 |
KR20020002463A (ko) | 2002-01-09 |
DE60018408D1 (de) | 2005-04-07 |
US20020137965A1 (en) | 2002-09-26 |
AU4772300A (en) | 2000-12-12 |
CN1203321C (zh) | 2005-05-25 |
CA2372572C (en) | 2008-12-02 |
CA2372572A1 (en) | 2000-11-30 |
WO2000071166A3 (en) | 2001-09-07 |
WO2000071166A2 (en) | 2000-11-30 |
KR100786476B1 (ko) | 2007-12-17 |
US7459144B2 (en) | 2008-12-02 |
AU775374B2 (en) | 2004-07-29 |
CN1357111A (zh) | 2002-07-03 |
EP1179189B1 (de) | 2005-03-02 |
DE60018408T2 (de) | 2005-12-29 |
RU2240828C2 (ru) | 2004-11-27 |
US20050152840A1 (en) | 2005-07-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |