ATE288586T1 - Detektierung neuraler aktivität - Google Patents
Detektierung neuraler aktivitätInfo
- Publication number
- ATE288586T1 ATE288586T1 AT99955537T AT99955537T ATE288586T1 AT E288586 T1 ATE288586 T1 AT E288586T1 AT 99955537 T AT99955537 T AT 99955537T AT 99955537 T AT99955537 T AT 99955537T AT E288586 T1 ATE288586 T1 AT E288586T1
- Authority
- AT
- Austria
- Prior art keywords
- neural activity
- activity
- detection
- compound
- pattern
- Prior art date
Links
- 230000001537 neural effect Effects 0.000 title abstract 6
- 238000001514 detection method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 210000005013 brain tissue Anatomy 0.000 abstract 2
- 230000000144 pharmacologic effect Effects 0.000 abstract 2
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5058—Neurological cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5085—Supracellular entities, e.g. tissue, organisms of invertebrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
- G01N2333/43595—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from coelenteratae, e.g. medusae
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Measuring Volume Flow (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9812127.0A GB9812127D0 (en) | 1998-06-06 | 1998-06-06 | Detection of neural activity |
| PCT/GB1999/001786 WO1999064859A1 (en) | 1998-06-06 | 1999-06-07 | Detection of neural activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE288586T1 true ATE288586T1 (de) | 2005-02-15 |
Family
ID=10833277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99955537T ATE288586T1 (de) | 1998-06-06 | 1999-06-07 | Detektierung neuraler aktivität |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7038106B1 (https=) |
| EP (1) | EP1084406B1 (https=) |
| JP (1) | JP4688293B2 (https=) |
| AT (1) | ATE288586T1 (https=) |
| DE (1) | DE69923556T2 (https=) |
| GB (1) | GB9812127D0 (https=) |
| WO (1) | WO1999064859A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6489535B1 (en) | 1999-03-18 | 2002-12-03 | The Board Of Trustees Of The Leland Stanford Junior University | Non-mammalian transgenic animal having an adult onset neurodegenerative phenotype |
| DK177327B1 (en) * | 2011-12-23 | 2013-01-14 | Entomopharm Aps | OPTIMIZED INSECT BASED EX VIVO MODEL FOR EXAMINATION OF BLOOD BRAIN BARRIER penetration and method of exposing the insect brain to chemical compounds |
| WO2013138948A1 (en) * | 2012-03-19 | 2013-09-26 | Rugen Therapeutics R & D (Shanghai) Co., Ltd. | Redox-sensitive calcium-sensor proteins and methods of use thereof |
| EP3254104B1 (en) * | 2015-02-04 | 2021-08-25 | Bristol-Myers Squibb Company | Methods of selecting therapeutic molecules |
| AU2016215155A1 (en) | 2015-02-04 | 2017-08-17 | F. Hoffmann-La Roche Ag | Tau antisense oligomers and uses thereof |
| CN106405029A (zh) * | 2016-11-15 | 2017-02-15 | 融安县植保植检站 | 金桔附生绿球藻药剂筛选试验系统 |
| WO2019241318A1 (en) * | 2018-06-13 | 2019-12-19 | Cornell University | Bioluminescent markers of neural activity |
| JP2022538231A (ja) * | 2019-06-25 | 2022-09-01 | モレキュラー デバイシーズ， エルエルシー | 生物学的細胞からの振動蛍光の分析 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3471793A (en) | 1992-01-24 | 1993-09-01 | Yale University | Assay for neuro-excitatory agents |
| US5714666A (en) * | 1993-02-09 | 1998-02-03 | Children's Hospital Of Philadelphia | Measurement of intracellular calcium using bioluminescent apoaequorin expressed in mammalian cells |
| FR2727017B1 (fr) * | 1994-11-21 | 1996-12-20 | Sophie Feldblum | Procede de criblage de facteurs sur modele de paralysie et methode d'obtention de ce modele |
| US5777195A (en) | 1996-05-17 | 1998-07-07 | The Rockefeller University | Knockout mutant mouse for DARPP-32 and use thereof |
-
1998
- 1998-06-06 GB GBGB9812127.0A patent/GB9812127D0/en not_active Ceased
-
1999
- 1999-06-07 AT AT99955537T patent/ATE288586T1/de not_active IP Right Cessation
- 1999-06-07 WO PCT/GB1999/001786 patent/WO1999064859A1/en not_active Ceased
- 1999-06-07 US US09/701,996 patent/US7038106B1/en not_active Expired - Fee Related
- 1999-06-07 JP JP2000553803A patent/JP4688293B2/ja not_active Expired - Fee Related
- 1999-06-07 DE DE69923556T patent/DE69923556T2/de not_active Expired - Lifetime
- 1999-06-07 EP EP99955537A patent/EP1084406B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US7038106B1 (en) | 2006-05-02 |
| DE69923556T2 (de) | 2006-01-26 |
| JP2002517754A (ja) | 2002-06-18 |
| WO1999064859A1 (en) | 1999-12-16 |
| DE69923556D1 (de) | 2005-03-10 |
| GB9812127D0 (en) | 1998-08-05 |
| EP1084406A1 (en) | 2001-03-21 |
| EP1084406B1 (en) | 2005-02-02 |
| JP4688293B2 (ja) | 2011-05-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |