ATE282041T1 - Aminomethylpyrrolochinazoline als thrombinrezeptor-antagonist - Google Patents
Aminomethylpyrrolochinazoline als thrombinrezeptor-antagonistInfo
- Publication number
- ATE282041T1 ATE282041T1 AT02706040T AT02706040T ATE282041T1 AT E282041 T1 ATE282041 T1 AT E282041T1 AT 02706040 T AT02706040 T AT 02706040T AT 02706040 T AT02706040 T AT 02706040T AT E282041 T1 ATE282041 T1 AT E282041T1
- Authority
- AT
- Austria
- Prior art keywords
- aminomethylpyrrolochinazoline
- thrombin receptor
- receptor antagonist
- par
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27098801P | 2001-02-23 | 2001-02-23 | |
US10/059,707 US6740657B2 (en) | 2001-02-23 | 2002-01-29 | Aminomethyl-pyrroloquinazoline compounds as thrombin receptor antagonists |
PCT/US2002/002489 WO2002068425A1 (en) | 2001-02-23 | 2002-01-29 | Aminomethyl-pyrroloquinazoline compounds as thrombin receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE282041T1 true ATE282041T1 (de) | 2004-11-15 |
Family
ID=26739081
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02706040T ATE282041T1 (de) | 2001-02-23 | 2002-01-29 | Aminomethylpyrrolochinazoline als thrombinrezeptor-antagonist |
Country Status (7)
Country | Link |
---|---|
US (1) | US6740657B2 (de) |
EP (1) | EP1370560B1 (de) |
JP (1) | JP2005500253A (de) |
AT (1) | ATE282041T1 (de) |
DE (1) | DE60201892T2 (de) |
ES (1) | ES2232735T3 (de) |
WO (1) | WO2002068425A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6346510B1 (en) | 1995-10-23 | 2002-02-12 | The Children's Medical Center Corporation | Therapeutic antiangiogenic endostatin compositions |
US20060142203A1 (en) * | 2002-06-26 | 2006-06-29 | Todd Hembrough | Compositions and methods comprising protein activated receptor antagonists |
US7262297B2 (en) * | 2003-05-15 | 2007-08-28 | Hoffmann-La Roche Inc. | Diaminopyrroloquinazolines compounds as protein tyrosine phosphatase inhibitors |
US7226915B2 (en) * | 2003-05-15 | 2007-06-05 | Hoffmann-La Roche Inc. | Diaminopyrroloquinazolines compounds as protein tyrosine phosphatase inhibitors |
EP1778652A2 (de) * | 2004-08-20 | 2007-05-02 | EntreMed, Inc. | Zusammensetzungen und verfahren mit proteinaseaktivierten rezeptorantagonisten |
WO2006046949A1 (en) * | 2004-10-22 | 2006-05-04 | Walter Reed Army Institute Of Research (Wrair) | SYNTHESIS AND ANTIMALARIAL ACTIVITY OF PYRROLO[3,2-f]QUINAZOLINE-1,3- DIAMINE DERIVATIVES |
US7253177B2 (en) | 2004-10-22 | 2007-08-07 | United States Of America As Represented By The Secretary Of The Army | Synthesis and antimalarial activity of pyrrolo[3,2-f]quinazoline-1,3-diamine derivatives |
TWI367112B (en) * | 2006-06-30 | 2012-07-01 | Schering Corp | Immediate-release tablet formulations of a thrombin receptor antagonist |
TWI343262B (en) * | 2006-09-26 | 2011-06-11 | Schering Corp | Rapidly disintegrating lyophilized oral formulations of a thrombin receptor antagonist |
EP2982756A1 (de) * | 2014-08-04 | 2016-02-10 | Berlin Cures Holding AG | Aptamere zur Verwendung gegen Erkrankungen im Zusammenhang mit Autoantikörpern |
CN115867354A (zh) * | 2020-07-02 | 2023-03-28 | 普林斯顿大学理事会 | 具有抗癌活性的化合物 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4118561A (en) | 1977-04-06 | 1978-10-03 | American Home Products Corporation | 7-(Substituted)-7H-pyrrolo[3,2-f]quinazoline-1,3-diamines |
US4208520A (en) | 1978-06-28 | 1980-06-17 | American Home Products Corporation | 7-(Substituted)-7H-pyrrolo[3,2-f]quinazoline-1,3-diamines |
US4451466A (en) | 1982-07-02 | 1984-05-29 | Shell Oil Company | Use of pyrroloquinazolinediamines as pesticides |
GB9123916D0 (en) * | 1991-11-11 | 1992-01-02 | Wellcome Found | Heterocyclic compounds |
WO2002012442A2 (en) * | 2000-08-07 | 2002-02-14 | Neurogen Corporation | Heterocyclic compounds as ligands of the gabaa receptor |
-
2002
- 2002-01-29 DE DE60201892T patent/DE60201892T2/de not_active Expired - Fee Related
- 2002-01-29 US US10/059,707 patent/US6740657B2/en not_active Expired - Lifetime
- 2002-01-29 EP EP02706040A patent/EP1370560B1/de not_active Expired - Lifetime
- 2002-01-29 ES ES02706040T patent/ES2232735T3/es not_active Expired - Lifetime
- 2002-01-29 JP JP2002567936A patent/JP2005500253A/ja active Pending
- 2002-01-29 AT AT02706040T patent/ATE282041T1/de not_active IP Right Cessation
- 2002-01-29 WO PCT/US2002/002489 patent/WO2002068425A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EP1370560A1 (de) | 2003-12-17 |
WO2002068425A1 (en) | 2002-09-06 |
ES2232735T3 (es) | 2005-06-01 |
US20020160963A1 (en) | 2002-10-31 |
DE60201892T2 (de) | 2005-11-03 |
DE60201892D1 (en) | 2004-12-16 |
US6740657B2 (en) | 2004-05-25 |
JP2005500253A (ja) | 2005-01-06 |
EP1370560B1 (de) | 2004-11-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |