ATE276273T1 - VIP ANALOGUE - Google Patents
VIP ANALOGUEInfo
- Publication number
- ATE276273T1 ATE276273T1 AT00952331T AT00952331T ATE276273T1 AT E276273 T1 ATE276273 T1 AT E276273T1 AT 00952331 T AT00952331 T AT 00952331T AT 00952331 T AT00952331 T AT 00952331T AT E276273 T1 ATE276273 T1 AT E276273T1
- Authority
- AT
- Austria
- Prior art keywords
- vip
- peptides
- alpha
- synthesis
- analogs
- Prior art date
Links
Landscapes
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The present invention encompasses novel analogs of vasoactive intestinal peptide (VIP), containing substitutions at appropriately selected amino acid s. The invention particularly relates to the design and synthesis of novel biologically active VIP analogs containing .alpha., .alpha.-dialkylated amin o acids in a site-specific manner. Specifically, the invention relates to the synthesis of VIP peptide derivatives, which bind selectively to VIP receptor s on target cells. The invention encompasses methods for the generation of the se peptides, compositions containing the peptides and the pharmacological applications of these peptides especially in the treatment and prevention of cancer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN136DE2000 | 2000-02-18 | ||
PCT/US2000/020871 WO2001060862A1 (en) | 2000-02-18 | 2000-07-31 | Vasoactive intestinal peptide analogs |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE276273T1 true ATE276273T1 (en) | 2004-10-15 |
Family
ID=11097028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00952331T ATE276273T1 (en) | 2000-02-18 | 2000-07-31 | VIP ANALOGUE |
Country Status (3)
Country | Link |
---|---|
AT (1) | ATE276273T1 (en) |
CA (1) | CA2405689A1 (en) |
DE (1) | DE60013912T2 (en) |
-
2000
- 2000-07-31 AT AT00952331T patent/ATE276273T1/en not_active IP Right Cessation
- 2000-07-31 DE DE60013912T patent/DE60013912T2/en not_active Expired - Fee Related
- 2000-07-31 CA CA002405689A patent/CA2405689A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE60013912D1 (en) | 2004-10-21 |
CA2405689A1 (en) | 2001-08-23 |
DE60013912T2 (en) | 2005-09-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR036196A1 (en) | MULTIMERIC CONTRACT AGENTS DIRECTED TO PEPTIDES | |
HK1088840A1 (en) | Stable analogs of glp-1 glp-1 | |
CY1107051T1 (en) | ANTI-ADVENTURES AND ANTI-ANGIROGENIC URKOKINING WASTES AND THEIR USE | |
HK1080363B (en) | Use of compounds having the biological activity of vasoactive intestinal peptide for the treatment of sarcoidosis | |
RS54215B1 (en) | Compositions and methods for diagnosing and treating cancer | |
FR06C0032I2 (en) | PROTEIN FORMULATIONS | |
DK1079849T3 (en) | Use of HMG proteins for the preparation of drugs with cytotoxic effect | |
DK1641820T3 (en) | From RasGap derived peptide to selectively kill cancer cells | |
JPS58116443A (en) | Novel peptide and manufacture | |
WO2001085777A3 (en) | Therapeutic pore-forming peptides | |
NO20026147L (en) | Thrombomodulin analogues for pharmaceutical use | |
GB2411404A (en) | Biologically active peptide conjugates | |
Krajewski et al. | Design and synthesis of dimeric HIV-1 integrase inhibitory peptides | |
MY126118A (en) | Somatostatin analogs for the treatment of cancer | |
DE602004028266D1 (en) | ANGIOGENIC PEPTIDES AND ITS USES | |
ATE276273T1 (en) | VIP ANALOGUE | |
MY117747A (en) | Vasoactive intestinal peptide analogs | |
AU2000265052A1 (en) | Somatostatin analogs for the treatment of cancer | |
Su et al. | Development of novel bone targeting peptide–drug conjugate of 13-aminomethyl-15-thiomatrine for osteoporosis therapy | |
ATE303401T1 (en) | FRAGMENTS OF THE VIRUS PROTEIN 2 OR 3 OF THE POLYOMAVIRUS AS TRAVIES FOR ACTIVE INGREDIENTS | |
Darwish et al. | Efficient synthesis of CN2097 using in situ activation of sulfhydryl group | |
TW200517125A (en) | Pharmaceutical composition for treatment of solid cancers | |
MY128151A (en) | Substance p analogs for the treatment of cancer | |
IL151211A0 (en) | Compositions useful for regulating parkin gene activity | |
Prasad et al. | Delivering multiple anticancer peptides as a single prodrug using lysyl‐lysine as a facile linker |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |