ATE276273T1 - VIP ANALOGUE - Google Patents

VIP ANALOGUE

Info

Publication number
ATE276273T1
ATE276273T1 AT00952331T AT00952331T ATE276273T1 AT E276273 T1 ATE276273 T1 AT E276273T1 AT 00952331 T AT00952331 T AT 00952331T AT 00952331 T AT00952331 T AT 00952331T AT E276273 T1 ATE276273 T1 AT E276273T1
Authority
AT
Austria
Prior art keywords
vip
peptides
alpha
synthesis
analogs
Prior art date
Application number
AT00952331T
Other languages
German (de)
Inventor
Anand C Burman
Sudhanand Prasad
Rama Mukherjee
Anu T Singh
Archna Mathur
Neena Gupta
Original Assignee
Dabur Res Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dabur Res Foundation filed Critical Dabur Res Foundation
Priority claimed from PCT/US2000/020871 external-priority patent/WO2001060862A1/en
Application granted granted Critical
Publication of ATE276273T1 publication Critical patent/ATE276273T1/en

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention encompasses novel analogs of vasoactive intestinal peptide (VIP), containing substitutions at appropriately selected amino acid s. The invention particularly relates to the design and synthesis of novel biologically active VIP analogs containing .alpha., .alpha.-dialkylated amin o acids in a site-specific manner. Specifically, the invention relates to the synthesis of VIP peptide derivatives, which bind selectively to VIP receptor s on target cells. The invention encompasses methods for the generation of the se peptides, compositions containing the peptides and the pharmacological applications of these peptides especially in the treatment and prevention of cancer.
AT00952331T 2000-02-18 2000-07-31 VIP ANALOGUE ATE276273T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN136DE2000 2000-02-18
PCT/US2000/020871 WO2001060862A1 (en) 2000-02-18 2000-07-31 Vasoactive intestinal peptide analogs

Publications (1)

Publication Number Publication Date
ATE276273T1 true ATE276273T1 (en) 2004-10-15

Family

ID=11097028

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00952331T ATE276273T1 (en) 2000-02-18 2000-07-31 VIP ANALOGUE

Country Status (3)

Country Link
AT (1) ATE276273T1 (en)
CA (1) CA2405689A1 (en)
DE (1) DE60013912T2 (en)

Also Published As

Publication number Publication date
DE60013912D1 (en) 2004-10-21
CA2405689A1 (en) 2001-08-23
DE60013912T2 (en) 2005-09-29

Similar Documents

Publication Publication Date Title
AR036196A1 (en) MULTIMERIC CONTRACT AGENTS DIRECTED TO PEPTIDES
HK1088840A1 (en) Stable analogs of glp-1 glp-1
CY1107051T1 (en) ANTI-ADVENTURES AND ANTI-ANGIROGENIC URKOKINING WASTES AND THEIR USE
HK1080363B (en) Use of compounds having the biological activity of vasoactive intestinal peptide for the treatment of sarcoidosis
RS54215B1 (en) Compositions and methods for diagnosing and treating cancer
FR06C0032I2 (en) PROTEIN FORMULATIONS
DK1079849T3 (en) Use of HMG proteins for the preparation of drugs with cytotoxic effect
DK1641820T3 (en) From RasGap derived peptide to selectively kill cancer cells
JPS58116443A (en) Novel peptide and manufacture
WO2001085777A3 (en) Therapeutic pore-forming peptides
NO20026147L (en) Thrombomodulin analogues for pharmaceutical use
GB2411404A (en) Biologically active peptide conjugates
Krajewski et al. Design and synthesis of dimeric HIV-1 integrase inhibitory peptides
MY126118A (en) Somatostatin analogs for the treatment of cancer
DE602004028266D1 (en) ANGIOGENIC PEPTIDES AND ITS USES
ATE276273T1 (en) VIP ANALOGUE
MY117747A (en) Vasoactive intestinal peptide analogs
AU2000265052A1 (en) Somatostatin analogs for the treatment of cancer
Su et al. Development of novel bone targeting peptide–drug conjugate of 13-aminomethyl-15-thiomatrine for osteoporosis therapy
ATE303401T1 (en) FRAGMENTS OF THE VIRUS PROTEIN 2 OR 3 OF THE POLYOMAVIRUS AS TRAVIES FOR ACTIVE INGREDIENTS
Darwish et al. Efficient synthesis of CN2097 using in situ activation of sulfhydryl group
TW200517125A (en) Pharmaceutical composition for treatment of solid cancers
MY128151A (en) Substance p analogs for the treatment of cancer
IL151211A0 (en) Compositions useful for regulating parkin gene activity
Prasad et al. Delivering multiple anticancer peptides as a single prodrug using lysyl‐lysine as a facile linker

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties