ATE275421T1 - Interleukin-12 und herpes simplex virusantigen enthaltende impfstoffe - Google Patents
Interleukin-12 und herpes simplex virusantigen enthaltende impfstoffeInfo
- Publication number
- ATE275421T1 ATE275421T1 AT99905946T AT99905946T ATE275421T1 AT E275421 T1 ATE275421 T1 AT E275421T1 AT 99905946 T AT99905946 T AT 99905946T AT 99905946 T AT99905946 T AT 99905946T AT E275421 T1 ATE275421 T1 AT E275421T1
- Authority
- AT
- Austria
- Prior art keywords
- herpes simplex
- simplex virus
- virus antigen
- vaccines containing
- containing interleukin
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 4
- 102000036639 antigens Human genes 0.000 title abstract 4
- 108091007433 antigens Proteins 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 102000013462 Interleukin-12 Human genes 0.000 title abstract 2
- 108010065805 Interleukin-12 Proteins 0.000 title abstract 2
- 241000700584 Simplexvirus Species 0.000 title abstract 2
- 229940117681 interleukin-12 Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 230000028993 immune response Effects 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5434—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55538—IL-12
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7450398P | 1998-02-12 | 1998-02-12 | |
| PCT/US1999/002923 WO1999040938A2 (en) | 1998-02-12 | 1999-02-10 | Vaccines comprising interleukin-12 and herpes simplex viral antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE275421T1 true ATE275421T1 (de) | 2004-09-15 |
Family
ID=22119907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99905946T ATE275421T1 (de) | 1998-02-12 | 1999-02-10 | Interleukin-12 und herpes simplex virusantigen enthaltende impfstoffe |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6488936B1 (https=) |
| EP (1) | EP1053017B1 (https=) |
| JP (1) | JP2002502884A (https=) |
| KR (1) | KR100622716B1 (https=) |
| CN (1) | CN1224422C (https=) |
| AT (1) | ATE275421T1 (https=) |
| AU (1) | AU764036B2 (https=) |
| BR (1) | BR9907883A (https=) |
| CA (1) | CA2320041A1 (https=) |
| DE (1) | DE69919984T2 (https=) |
| DK (1) | DK1053017T3 (https=) |
| ES (1) | ES2226338T3 (https=) |
| IL (1) | IL137811A (https=) |
| PT (1) | PT1053017E (https=) |
| WO (1) | WO1999040938A2 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ515322A (en) * | 1999-05-13 | 2004-03-26 | Wyeth Corp | Adjuvant combination formulations |
| ES2258987T3 (es) * | 1999-12-17 | 2006-09-16 | Wyeth Holdings Corporation | Vacuna para reforzar las respuestas inmunitarias al virus del herpes simple. |
| US20070025958A1 (en) | 2000-10-27 | 2007-02-01 | Hadden John W | Vaccine immunotherapy |
| AU2002232560A1 (en) | 2000-10-27 | 2002-05-06 | Immuno-Rx, Inc | Vaccine immunotherapy for immune suppressed patients |
| IL155690A0 (en) * | 2000-11-10 | 2003-11-23 | Wyeth Corp | Adjuvant combination formulations |
| US6867000B2 (en) | 2000-12-07 | 2005-03-15 | Wyeth Holdings Corporation | Method of enhancing immune responses to herpes |
| JP2004099584A (ja) * | 2002-05-02 | 2004-04-02 | Keio Gijuku | Ｈｓｖを用いた抗腫瘍剤 |
| CN1301749C (zh) * | 2005-12-09 | 2007-02-28 | 复旦大学 | 抗单纯疱疹病毒－2感染的多表位dna疫苗及其制备方法 |
| US7790203B2 (en) * | 2005-12-13 | 2010-09-07 | Lowder Tom R | Composition and regimen for the treatment of herpes simplex virus, herpes zoster, and herpes genitalia epidermal herpetic lesions |
| PL2068918T5 (pl) | 2006-09-26 | 2024-12-02 | Access To Advanced Health Institute | Kompozycja szczepionki zawierająca syntetyczny adiuwant |
| US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| CA3017298C (en) | 2009-05-15 | 2021-09-28 | Irx Therapeutics, Inc. | Compositions comprising primary cell-derived biologics for enhancing immune responses in patients |
| CA2764374C (en) | 2009-06-05 | 2019-11-19 | Infectious Disease Research Institute | Synthetic glucopyranosyl lipid adjuvants |
| US8729058B2 (en) | 2009-10-27 | 2014-05-20 | Michael Zasloff | Methods and compositions for treating and preventing viral infections |
| ES2667476T3 (es) | 2009-12-08 | 2018-05-11 | Irx Therapeutics, Inc. | Método para invertir la supresión inmunitaria de células de Langerhans |
| EA027236B1 (ru) | 2011-04-08 | 2017-07-31 | Иммьюн Дизайн Корп. | Иммуногенные композиции и способы применения таких композиций для индукции гуморального и клеточного иммунного ответа |
| HRP20181102T1 (hr) | 2012-05-16 | 2018-09-07 | Immune Design Corp | Cjepiva za hsv-2 |
| MX370573B (es) | 2013-04-18 | 2019-12-17 | Immune Design Corp | Monoterapia con glucopiranosil lipido a para usarse en el tratamiento del cancer. |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| WO2017196943A1 (en) | 2016-05-10 | 2017-11-16 | Minneapolis Medical Research Foundation | Cytokine signaling immunomodulators and methods |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994022473A1 (en) * | 1993-04-01 | 1994-10-13 | University Of Washington | Use of interleukin 7 to improve vaccine potency |
| US5571515A (en) * | 1994-04-18 | 1996-11-05 | The Wistar Institute Of Anatomy & Biology | Compositions and methods for use of IL-12 as an adjuvant |
| IL114576A0 (en) * | 1994-07-22 | 1995-11-27 | Merck & Co Inc | Polynucleotide herpes virus vaccine |
| GB9422990D0 (en) * | 1994-11-15 | 1995-01-04 | Cortecs Ltd | Immunogenic compositions |
| WO1998008947A1 (en) * | 1995-12-19 | 1998-03-05 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Enhancement of dna immunization through the use of cytokines |
-
1999
- 1999-02-10 JP JP2000531189A patent/JP2002502884A/ja active Pending
- 1999-02-10 AT AT99905946T patent/ATE275421T1/de not_active IP Right Cessation
- 1999-02-10 WO PCT/US1999/002923 patent/WO1999040938A2/en not_active Ceased
- 1999-02-10 CN CNB998043311A patent/CN1224422C/zh not_active Expired - Fee Related
- 1999-02-10 BR BR9907883A patent/BR9907883A/pt not_active Application Discontinuation
- 1999-02-10 US US09/247,635 patent/US6488936B1/en not_active Expired - Fee Related
- 1999-02-10 EP EP19990905946 patent/EP1053017B1/en not_active Expired - Lifetime
- 1999-02-10 DE DE1999619984 patent/DE69919984T2/de not_active Expired - Fee Related
- 1999-02-10 IL IL13781199A patent/IL137811A/en not_active IP Right Cessation
- 1999-02-10 CA CA 2320041 patent/CA2320041A1/en not_active Abandoned
- 1999-02-10 KR KR1020007008769A patent/KR100622716B1/ko not_active Expired - Fee Related
- 1999-02-10 DK DK99905946T patent/DK1053017T3/da active
- 1999-02-10 AU AU25981/99A patent/AU764036B2/en not_active Ceased
- 1999-02-10 ES ES99905946T patent/ES2226338T3/es not_active Expired - Lifetime
- 1999-02-10 PT PT99905946T patent/PT1053017E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999040938A2 (en) | 1999-08-19 |
| JP2002502884A (ja) | 2002-01-29 |
| KR100622716B1 (ko) | 2006-09-13 |
| EP1053017B1 (en) | 2004-09-08 |
| IL137811A0 (en) | 2001-10-31 |
| CA2320041A1 (en) | 1999-08-19 |
| CN1299287A (zh) | 2001-06-13 |
| IL137811A (en) | 2005-12-18 |
| EP1053017A2 (en) | 2000-11-22 |
| WO1999040938A3 (en) | 2000-08-24 |
| DE69919984T2 (de) | 2005-11-17 |
| BR9907883A (pt) | 2000-11-14 |
| KR20010040867A (ko) | 2001-05-15 |
| AU764036B2 (en) | 2003-08-07 |
| ES2226338T3 (es) | 2005-03-16 |
| DK1053017T3 (da) | 2004-11-22 |
| CN1224422C (zh) | 2005-10-26 |
| PT1053017E (pt) | 2004-12-31 |
| DE69919984D1 (de) | 2004-10-14 |
| AU2598199A (en) | 1999-08-30 |
| US6488936B1 (en) | 2002-12-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1053017 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |