ATE260261T1 - Oligobenzimidazolderivate und ihre verwendung als dna-transfektionsmittel - Google Patents
Oligobenzimidazolderivate und ihre verwendung als dna-transfektionsmittelInfo
- Publication number
- ATE260261T1 ATE260261T1 AT00976109T AT00976109T ATE260261T1 AT E260261 T1 ATE260261 T1 AT E260261T1 AT 00976109 T AT00976109 T AT 00976109T AT 00976109 T AT00976109 T AT 00976109T AT E260261 T1 ATE260261 T1 AT E260261T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acids
- group
- dna transfection
- transfection agents
- vivo
- Prior art date
Links
- 238000001890 transfection Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 101100294106 Caenorhabditis elegans nhr-3 gene Proteins 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 230000000007 visual effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9913934A FR2800736B1 (fr) | 1999-11-05 | 1999-11-05 | Derives d'oligobenzimidazoles, les compositions les contenant et leurs utilisations |
| US17464800P | 2000-01-05 | 2000-01-05 | |
| PCT/FR2000/003087 WO2001032630A1 (fr) | 1999-11-05 | 2000-11-06 | Derives d'oligobenzimidazoles et leur utilisation comme agents de transfection d'adn |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE260261T1 true ATE260261T1 (de) | 2004-03-15 |
Family
ID=26235148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00976109T ATE260261T1 (de) | 1999-11-05 | 2000-11-06 | Oligobenzimidazolderivate und ihre verwendung als dna-transfektionsmittel |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1230223B1 (de) |
| JP (1) | JP2003513078A (de) |
| AT (1) | ATE260261T1 (de) |
| AU (1) | AU1399801A (de) |
| CA (1) | CA2389778A1 (de) |
| DE (1) | DE60008573T2 (de) |
| DK (1) | DK1230223T3 (de) |
| ES (1) | ES2211644T3 (de) |
| IL (1) | IL149153A0 (de) |
| MX (1) | MXPA02004449A (de) |
| PT (1) | PT1230223E (de) |
| WO (1) | WO2001032630A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0320627D0 (en) * | 2003-09-03 | 2003-10-01 | Imp College Innovations Ltd | Methods |
| GB201506660D0 (en) | 2015-04-20 | 2015-06-03 | Cellcentric Ltd | Pharmaceutical compounds |
| GB201506658D0 (en) | 2015-04-20 | 2015-06-03 | Cellcentric Ltd | Pharmaceutical compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ207393A (en) * | 1983-08-05 | 1987-03-31 | Neal Lloyd First | Staining dna in living cells |
| NZ239893A (en) * | 1990-09-25 | 1993-11-25 | Hoechst Japan | A method for introducing a foreign dna into a cell |
-
2000
- 2000-11-06 MX MXPA02004449A patent/MXPA02004449A/es unknown
- 2000-11-06 IL IL14915300A patent/IL149153A0/xx unknown
- 2000-11-06 EP EP00976109A patent/EP1230223B1/de not_active Expired - Lifetime
- 2000-11-06 AT AT00976109T patent/ATE260261T1/de not_active IP Right Cessation
- 2000-11-06 CA CA002389778A patent/CA2389778A1/fr not_active Abandoned
- 2000-11-06 WO PCT/FR2000/003087 patent/WO2001032630A1/fr not_active Ceased
- 2000-11-06 DK DK00976109T patent/DK1230223T3/da active
- 2000-11-06 ES ES00976109T patent/ES2211644T3/es not_active Expired - Lifetime
- 2000-11-06 JP JP2001534781A patent/JP2003513078A/ja not_active Withdrawn
- 2000-11-06 AU AU13998/01A patent/AU1399801A/en not_active Abandoned
- 2000-11-06 DE DE60008573T patent/DE60008573T2/de not_active Expired - Fee Related
- 2000-11-06 PT PT00976109T patent/PT1230223E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1230223T3 (da) | 2004-06-14 |
| JP2003513078A (ja) | 2003-04-08 |
| EP1230223A1 (de) | 2002-08-14 |
| MXPA02004449A (es) | 2002-09-02 |
| WO2001032630A1 (fr) | 2001-05-10 |
| ES2211644T3 (es) | 2004-07-16 |
| DE60008573D1 (de) | 2004-04-01 |
| PT1230223E (pt) | 2004-07-30 |
| CA2389778A1 (fr) | 2001-05-10 |
| IL149153A0 (en) | 2002-11-10 |
| AU1399801A (en) | 2001-05-14 |
| EP1230223B1 (de) | 2004-02-25 |
| DE60008573T2 (de) | 2004-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1230223 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |