ATE2522T1 - Dibenz(b,f)(1,4)oxazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen. - Google Patents

Dibenz(b,f)(1,4)oxazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen.

Info

Publication number
ATE2522T1
ATE2522T1 AT79104986T AT79104986T ATE2522T1 AT E2522 T1 ATE2522 T1 AT E2522T1 AT 79104986 T AT79104986 T AT 79104986T AT 79104986 T AT79104986 T AT 79104986T AT E2522 T1 ATE2522 T1 AT E2522T1
Authority
AT
Austria
Prior art keywords
dibenz
oxazepines
processes
production
pharmaceutical compositions
Prior art date
Application number
AT79104986T
Other languages
English (en)
Inventor
Masuo Koizumi
Kazuo Sasahara
Yasushi Murakami
Sakae Wada
Hiroshi Nakakimura
Noboru Kubodera
Shun-Ichi Hata
Original Assignee
Chugai Seiyaku Kabushiki Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15485754&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE2522(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chugai Seiyaku Kabushiki Kaisha filed Critical Chugai Seiyaku Kabushiki Kaisha
Application granted granted Critical
Publication of ATE2522T1 publication Critical patent/ATE2522T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D267/20—[b, f]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT79104986T 1978-12-06 1979-12-06 Dibenz(b,f)(1,4)oxazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen. ATE2522T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14993478A JPS5576869A (en) 1978-12-06 1978-12-06 Dibenzoxazepine derivative and its preparation
EP79104986A EP0012385B1 (de) 1978-12-06 1979-12-06 Dibenz(b,f)(1,4)oxazepine, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE2522T1 true ATE2522T1 (de) 1983-03-15

Family

ID=15485754

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79104986T ATE2522T1 (de) 1978-12-06 1979-12-06 Dibenz(b,f)(1,4)oxazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen.

Country Status (10)

Country Link
US (1) US4290953A (de)
EP (1) EP0012385B1 (de)
JP (1) JPS5576869A (de)
AT (1) ATE2522T1 (de)
CA (1) CA1132545A (de)
DE (1) DE2964868D1 (de)
HU (1) HU178462B (de)
IL (1) IL58758A (de)
MX (1) MX6213E (de)
ZA (1) ZA796457B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56166180A (en) 1980-05-28 1981-12-21 Chugai Pharmaceut Co Ltd Dibenzoxazepine derivative and its preparation
US5182272A (en) * 1991-05-03 1993-01-26 G. D. Searle & Co. 8-substituted-dibenz[b,f][1,4]oxazepine-10(11)-carboxylic acid, substituted hydrazides, pharmaceutical compositions, and methods for treating pain
US5180720A (en) * 1991-05-03 1993-01-19 G. D. Searle & Co. 2- and 3-alkoxy or hydroxy-8-substituted-dibenz[b,f]-[1,4]oxazepine-10(11H)-carboxylic acid, substituted hydrazides and methods for treating pain
US5378840A (en) * 1992-04-16 1995-01-03 G. D. Searle & Co. Substituted dibenzoxazepine compounds
WO1993007132A1 (en) * 1991-10-01 1993-04-15 G.D. Searle & Co. 10-acyl-dibenz(b,f)(1,4)-oxazepines and their thiazepines and diazepines analogues useful as prostaglandin antagonists
US5212169A (en) * 1991-10-31 1993-05-18 G. D. Searle & Co. Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain
US5449674A (en) * 1991-11-05 1995-09-12 G. D. Searle & Co. 2-,3-,5-, and/or 8-substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain
WO1993013082A1 (en) * 1991-12-20 1993-07-08 G.D. Searle & Co. Substituted dibenzoxazepines or dibenzothiazepines and their use as prostaglandin e2 antagonists
US5304644A (en) * 1992-04-15 1994-04-19 G. D. Searle & Co. 1-,2-,3-,4-,5-,6-,7-,8- and/or 9 substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain
US5449673A (en) * 1992-08-13 1995-09-12 G. D. Searle & Co. 10,11-dihydro-10-(3-substituted-1-oxo-2-propyl, propenyl or propynyl)dibenz[b,f][1,4] oxazepine prostaglandin antagonists
US5395932A (en) * 1993-04-30 1995-03-07 G. D. Searle & Co. 2,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5354746A (en) * 1993-06-01 1994-10-11 G. D. Searle & Co. Squaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5354747A (en) * 1993-06-16 1994-10-11 G. D. Searle & Co. 2-, 3-, 4-, 5-, 6-, 7-, 8-, 9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use
US5461047A (en) * 1993-06-16 1995-10-24 G. D. Searle & Co. 2-,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use
US5424424A (en) * 1993-10-07 1995-06-13 G. D. Searle & Co. Tartaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5420270A (en) * 1993-10-07 1995-05-30 G. D. Searle & Co. Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5488046A (en) * 1993-11-03 1996-01-30 G. D. Searle & Co. Carbamic acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5449675A (en) * 1994-06-09 1995-09-12 G. D. Searle & Co. Substituted dibenzoxazepine and dibenzthiazepine urea compounds, pharmaceutical compositions and methods of use
US5441950A (en) * 1994-06-09 1995-08-15 G. D. Searle & Co. Substituted dibenzoxazepine and dibenzthiazepine carbamate compounds, pharmaceutical compositions and methods of use
US7395122B2 (en) * 2001-07-13 2008-07-01 Siemens Aktiengesellschaft Data capture for electronically delivered automation services
WO2019173761A1 (en) 2018-03-09 2019-09-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services C-abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3458516A (en) * 1968-02-16 1969-07-29 American Cyanamid Co 11-(piperazinyl)dibenz(b,f)(1,4)oxazepines and analogous thiazepines
US3793345A (en) * 1972-08-02 1974-02-19 Squibb & Sons Inc 5,11-dihydrodibenz(b,e)(1,4)oxazepine-5-alkylamidoximes
US3992375A (en) * 1974-08-12 1976-11-16 G. D. Searle & Co. Dibenzoxazepine N-carboxylic acid hydrazines and derivatives
GB1522003A (en) * 1975-10-17 1978-08-23 Searle & Co 1-acyl-2-(8-chloro-10,11-dihydrodibenz-(b,f)(1,4)-oxazepine-10-carbonyl)hydrazines
US4045442A (en) * 1976-01-05 1977-08-30 G. D. Searle & Co. 1-(Substituted amino)alkanoyl-2-(dibenzoxazepine-10-carbonyl)hydrazines and derivatives thereof
US4170593A (en) * 1976-01-05 1979-10-09 G. D. Searle & Co. 1-(Substituted amino)alkanoyl-2-(dibenzoxapine-10-carbonyl)hydrazines and derivatives thereof

Also Published As

Publication number Publication date
IL58758A (en) 1983-02-23
DE2964868D1 (en) 1983-03-24
EP0012385B1 (de) 1983-02-16
CA1132545A (en) 1982-09-28
JPS5576869A (en) 1980-06-10
ZA796457B (en) 1980-11-26
MX6213E (es) 1984-12-19
US4290953A (en) 1981-09-22
HU178462B (en) 1982-05-28
EP0012385A1 (de) 1980-06-25

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee