ATE250041T1 - Ein verbessertes verfahren zur herstellung von 3, 5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazin - Google Patents
Ein verbessertes verfahren zur herstellung von 3, 5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazinInfo
- Publication number
- ATE250041T1 ATE250041T1 AT99956293T AT99956293T ATE250041T1 AT E250041 T1 ATE250041 T1 AT E250041T1 AT 99956293 T AT99956293 T AT 99956293T AT 99956293 T AT99956293 T AT 99956293T AT E250041 T1 ATE250041 T1 AT E250041T1
- Authority
- AT
- Austria
- Prior art keywords
- yield
- dichlorophenyl
- diamino
- triazine
- improved method
- Prior art date
Links
- PYZRQGJRPPTADH-UHFFFAOYSA-N lamotrigine Chemical compound NC1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl PYZRQGJRPPTADH-UHFFFAOYSA-N 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 5
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
- FIBBFBXFASKAON-UHFFFAOYSA-N 2,3-dichlorobenzoyl cyanide Chemical compound ClC1=CC=CC(C(=O)C#N)=C1Cl FIBBFBXFASKAON-UHFFFAOYSA-N 0.000 abstract 2
- 230000003993 interaction Effects 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- YBONBWJSFMTXLE-UHFFFAOYSA-N 2,3-dichlorobenzoyl chloride Chemical compound ClC(=O)C1=CC=CC(Cl)=C1Cl YBONBWJSFMTXLE-UHFFFAOYSA-N 0.000 abstract 1
- HAMNKKUPIHEESI-UHFFFAOYSA-N aminoguanidine Chemical compound NNC(N)=N HAMNKKUPIHEESI-UHFFFAOYSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- DOBRDRYODQBAMW-UHFFFAOYSA-N copper(i) cyanide Chemical compound [Cu+].N#[C-] DOBRDRYODQBAMW-UHFFFAOYSA-N 0.000 abstract 1
- 239000006184 cosolvent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
Landscapes
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2171CA1998 IN183150B (enExample) | 1998-12-14 | 1998-12-14 | |
| PCT/IB1999/001955 WO2000035888A1 (en) | 1998-12-14 | 1999-12-07 | An improved process for the preparation of 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE250041T1 true ATE250041T1 (de) | 2003-10-15 |
Family
ID=11087296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99956293T ATE250041T1 (de) | 1998-12-14 | 1999-12-07 | Ein verbessertes verfahren zur herstellung von 3, 5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazin |
Country Status (4)
| Country | Link |
|---|---|
| AT (1) | ATE250041T1 (enExample) |
| DE (1) | DE69911462T2 (enExample) |
| IN (1) | IN183150B (enExample) |
| RU (1) | RU2231526C2 (enExample) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0021121B1 (en) * | 1979-06-01 | 1983-05-11 | The Wellcome Foundation Limited | 1,2,4-triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them |
-
1998
- 1998-12-14 IN IN2171CA1998 patent/IN183150B/en unknown
-
1999
- 1999-12-07 DE DE69911462T patent/DE69911462T2/de not_active Expired - Fee Related
- 1999-12-07 RU RU2001115698/04A patent/RU2231526C2/ru not_active IP Right Cessation
- 1999-12-07 AT AT99956293T patent/ATE250041T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69911462D1 (de) | 2003-10-23 |
| IN183150B (enExample) | 1999-09-25 |
| DE69911462T2 (de) | 2004-07-01 |
| RU2231526C2 (ru) | 2004-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |