ATE249478T1 - Harnstoff- und thioharnstoffderivate von antibiotisch wirksamen glykopeptiden - Google Patents

Harnstoff- und thioharnstoffderivate von antibiotisch wirksamen glykopeptiden

Info

Publication number
ATE249478T1
ATE249478T1 AT98303494T AT98303494T ATE249478T1 AT E249478 T1 ATE249478 T1 AT E249478T1 AT 98303494 T AT98303494 T AT 98303494T AT 98303494 T AT98303494 T AT 98303494T AT E249478 T1 ATE249478 T1 AT E249478T1
Authority
AT
Austria
Prior art keywords
urea
thiourea derivatives
antibiotic glycopeptides
derivatives
glycopeptides
Prior art date
Application number
AT98303494T
Other languages
English (en)
Inventor
Richard Craig Thompson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE249478T1 publication Critical patent/ATE249478T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT98303494T 1997-05-20 1998-05-05 Harnstoff- und thioharnstoffderivate von antibiotisch wirksamen glykopeptiden ATE249478T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4719697P 1997-05-20 1997-05-20

Publications (1)

Publication Number Publication Date
ATE249478T1 true ATE249478T1 (de) 2003-09-15

Family

ID=21947590

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98303494T ATE249478T1 (de) 1997-05-20 1998-05-05 Harnstoff- und thioharnstoffderivate von antibiotisch wirksamen glykopeptiden

Country Status (10)

Country Link
US (1) US5919771A (de)
EP (1) EP0881230B1 (de)
JP (1) JP4086326B2 (de)
AT (1) ATE249478T1 (de)
AU (1) AU7285498A (de)
CA (1) CA2290388A1 (de)
DE (1) DE69817915T2 (de)
ES (1) ES2206839T3 (de)
PT (1) PT881230E (de)
WO (1) WO1998052592A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1140993T3 (da) 1998-12-23 2003-10-06 Theravance Inc Glycopeptidderivater og farmaceutiske præparater indeholdende dem
MX2007006319A (es) 2004-11-29 2007-07-25 Univ Nagoya Nat Univ Corp Derivados de monomeros de glicopeptico antibioticos.
WO2007038246A2 (en) 2005-09-22 2007-04-05 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
EP1926780B1 (de) 2005-09-22 2013-08-14 Medivas, LLC Bis-( -amino)-diol-diester-haltige poly(esteramid) und poly(esterurethan)-zusammensetzungen und verwendungsverfahren
CA2710417A1 (en) 2007-12-26 2009-07-02 Shionogi & Co., Ltd. Glycosylated glycopeptide antibiotic derivatives
US8841440B2 (en) 2008-04-01 2014-09-23 Cornell University Organo-soluble chitosan salts and chitosan-derived biomaterials prepared thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4698327A (en) * 1985-04-25 1987-10-06 Eli Lilly And Company Novel glycopeptide derivatives
US4643987A (en) * 1985-08-14 1987-02-17 Eli Lilly And Company Modified glycopeptides
US5534420A (en) * 1988-07-28 1996-07-09 Eli Lilly And Company Biotransformation of glycopeptide antibiotics
DK0409045T3 (da) * 1989-07-18 1997-12-22 Biosearch Italia Spa Pentapeptidantibiotika afledt fra dalbaheptider.
NZ236393A (en) * 1989-12-13 1992-05-26 Lilly Co Eli N-alkylated glycopeptide derivatives prepared from antibiotics a82846 series and pa-42867-a; pharmaceutical compositions
TW213468B (de) * 1991-06-29 1993-09-21 Hoechst Ag
NZ270387A (en) * 1994-01-28 1996-11-26 Lilly Co Eli Glycopeptide antibiotic, its production and compositions thereof
US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
AU2441697A (en) * 1996-04-12 1997-11-07 Eli Lilly And Company Covalently-linked glycopeptide dimers
US5919756A (en) * 1996-06-28 1999-07-06 Eli Lilly And Company Amides

Also Published As

Publication number Publication date
JP2001526682A (ja) 2001-12-18
DE69817915T2 (de) 2004-07-15
AU7285498A (en) 1998-12-11
EP0881230A3 (de) 1998-12-23
PT881230E (pt) 2004-02-27
CA2290388A1 (en) 1998-11-26
US5919771A (en) 1999-07-06
EP0881230A2 (de) 1998-12-02
WO1998052592A1 (en) 1998-11-26
JP4086326B2 (ja) 2008-05-14
ES2206839T3 (es) 2004-05-16
DE69817915D1 (de) 2003-10-16
EP0881230B1 (de) 2003-09-10

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