ATE239719T1 - Kondensierte 4,5,6,7-tetrahydrobenzo c)thiophene als beschleuniger der wirkung des - Google Patents
Kondensierte 4,5,6,7-tetrahydrobenzo c)thiophene als beschleuniger der wirkung desInfo
- Publication number
- ATE239719T1 ATE239719T1 AT97939185T AT97939185T ATE239719T1 AT E239719 T1 ATE239719 T1 AT E239719T1 AT 97939185 T AT97939185 T AT 97939185T AT 97939185 T AT97939185 T AT 97939185T AT E239719 T1 ATE239719 T1 AT E239719T1
- Authority
- AT
- Austria
- Prior art keywords
- optionally
- hydrocarbon group
- optionally substituted
- oxygen atom
- sulfur atom
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 3
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title 2
- 229930192474 thiophene Natural products 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 125000004434 sulfur atom Chemical group 0.000 abstract 2
- VUDQSRFCCHQIIU-UHFFFAOYSA-N 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one Chemical compound CCCCCC(=O)C1=C(O)C(Cl)=C(OC)C(Cl)=C1O VUDQSRFCCHQIIU-UHFFFAOYSA-N 0.000 abstract 1
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- 208000010392 Bone Fractures Diseases 0.000 abstract 1
- 208000020084 Bone disease Diseases 0.000 abstract 1
- 101000942967 Homo sapiens Leukemia inhibitory factor Proteins 0.000 abstract 1
- 102100032352 Leukemia inhibitory factor Human genes 0.000 abstract 1
- 102000005741 Metalloproteases Human genes 0.000 abstract 1
- 108010006035 Metalloproteases Proteins 0.000 abstract 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 206010056677 Nerve degeneration Diseases 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 230000024245 cell differentiation Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 230000009401 metastasis Effects 0.000 abstract 1
- 201000008482 osteoarthritis Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23700696 | 1996-09-06 | ||
| PCT/JP1997/003122 WO1998009958A1 (en) | 1996-09-06 | 1997-09-05 | Condensed 4,5,6,7-tetrahydrobenzo[c]thiophenes as enhancer for cell differentiation induction factor action |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE239719T1 true ATE239719T1 (de) | 2003-05-15 |
Family
ID=17008997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97939185T ATE239719T1 (de) | 1996-09-06 | 1997-09-05 | Kondensierte 4,5,6,7-tetrahydrobenzo c)thiophene als beschleuniger der wirkung des |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US6066658A (de) |
| EP (1) | EP0931074B1 (de) |
| AT (1) | ATE239719T1 (de) |
| AU (1) | AU4135397A (de) |
| CA (1) | CA2263583A1 (de) |
| DE (1) | DE69721794T2 (de) |
| WO (1) | WO1998009958A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5196099A (en) * | 1998-08-12 | 2000-03-06 | Takeda Chemical Industries Ltd. | Enhancer of cell differentiation induction factor |
| WO2000018765A1 (fr) * | 1998-09-30 | 2000-04-06 | Taisho Pharmaceutical Co., Ltd. | Composes d'isoxazolylthiophene substitue |
| US20030158245A1 (en) * | 2000-03-31 | 2003-08-21 | Tsuneo Yasuma | Fused heterocyclic derivatives, their production and use |
| AU5880801A (en) * | 2000-05-23 | 2001-12-03 | Takeda Chemical Industries Ltd. | Medicinal compositions containing thiophene derivatives |
| US20030185878A1 (en) * | 2000-06-23 | 2003-10-02 | Tetsuo Hoshino | Process for producing phospholipid-containing drug |
| US6902881B2 (en) * | 2000-10-13 | 2005-06-07 | President And Fellows Of Harvard College | Compounds and methods for regulating cell differentiation |
| WO2002078673A1 (fr) * | 2001-03-29 | 2002-10-10 | Takeda Chemical Industries, Ltd. | Procede de production d'un medicament sous forme de granules fins |
| AU2002303191B2 (en) | 2001-03-30 | 2007-01-18 | King Pharmaceuticals, Inc. | Pharmaceutically active compounds and methods of use |
| WO2002092606A1 (fr) * | 2001-05-15 | 2002-11-21 | Takeda Chemical Industries, Ltd. | Derives d'imidazolidine fusionnes, leur procede de preparation et d'utilisation |
| EP1640010A1 (de) * | 2003-07-01 | 2006-03-29 | Astellas Pharma Inc. | Mittel zur einleitung einer zunahme der knochenmasse |
| US8697139B2 (en) | 2004-09-21 | 2014-04-15 | Frank M. Phillips | Method of intervertebral disc treatment using articular chondrocyte cells |
| TWI356301B (en) * | 2007-12-27 | 2012-01-11 | Ind Tech Res Inst | Memory management system and method for open platf |
| US8815592B2 (en) | 2010-04-21 | 2014-08-26 | Research Development Foundation | Methods and compositions related to dopaminergic neuronal cells |
| US20130184272A1 (en) | 2010-09-17 | 2013-07-18 | Takeda Pharmaceutical Company Limited | Diabetes therapeutic agent |
| WO2017189553A1 (en) * | 2016-04-25 | 2017-11-02 | Everon Biosciences, Inc. | Removal of senescence-associated macrophages |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08175992A (ja) * | 1994-12-21 | 1996-07-09 | Sagami Chem Res Center | 神経成長因子産生促進剤および縮環型オキサゾール化合物 |
| JPH08245386A (ja) * | 1995-03-09 | 1996-09-24 | Takeda Chem Ind Ltd | 細胞分化誘導因子作用増強剤 |
-
1997
- 1997-09-05 AU AU41353/97A patent/AU4135397A/en not_active Abandoned
- 1997-09-05 DE DE69721794T patent/DE69721794T2/de not_active Expired - Lifetime
- 1997-09-05 EP EP97939185A patent/EP0931074B1/de not_active Expired - Lifetime
- 1997-09-05 CA CA002263583A patent/CA2263583A1/en not_active Abandoned
- 1997-09-05 AT AT97939185T patent/ATE239719T1/de not_active IP Right Cessation
- 1997-09-05 WO PCT/JP1997/003122 patent/WO1998009958A1/en active IP Right Grant
-
1999
- 1999-02-19 US US09/252,913 patent/US6066658A/en not_active Expired - Fee Related
-
2000
- 2000-04-28 US US09/559,453 patent/US6242471B1/en not_active Expired - Fee Related
-
2001
- 2001-05-03 US US09/847,416 patent/US6391905B1/en not_active Expired - Fee Related
-
2002
- 2002-03-26 US US10/105,333 patent/US6489351B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0931074B1 (de) | 2003-05-07 |
| WO1998009958A1 (en) | 1998-03-12 |
| US6489351B1 (en) | 2002-12-03 |
| EP0931074A1 (de) | 1999-07-28 |
| CA2263583A1 (en) | 1998-03-12 |
| US6242471B1 (en) | 2001-06-05 |
| US6391905B1 (en) | 2002-05-21 |
| US20020049242A1 (en) | 2002-04-25 |
| DE69721794D1 (de) | 2003-06-12 |
| DE69721794T2 (de) | 2004-03-18 |
| AU4135397A (en) | 1998-03-26 |
| US6066658A (en) | 2000-05-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |