ATE236907T1 - Misoprostol, verfahren zur deren herstellung mit verwendung eines organometall-kupferkomplexes - Google Patents
Misoprostol, verfahren zur deren herstellung mit verwendung eines organometall-kupferkomplexesInfo
- Publication number
- ATE236907T1 ATE236907T1 AT97303062T AT97303062T ATE236907T1 AT E236907 T1 ATE236907 T1 AT E236907T1 AT 97303062 T AT97303062 T AT 97303062T AT 97303062 T AT97303062 T AT 97303062T AT E236907 T1 ATE236907 T1 AT E236907T1
- Authority
- AT
- Austria
- Prior art keywords
- misoprostol
- reaction
- organometall
- production
- copper complex
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- OJLOPKGSLYJEMD-URPKTTJQSA-N methyl 7-[(1r,2r,3r)-3-hydroxy-2-[(1e)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl]heptanoate Chemical compound CCCCC(C)(O)C\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC OJLOPKGSLYJEMD-URPKTTJQSA-N 0.000 title abstract 2
- 229960005249 misoprostol Drugs 0.000 title abstract 2
- -1 alkyl lithium compound Chemical class 0.000 abstract 3
- 125000002524 organometallic group Chemical group 0.000 abstract 2
- BZKFMUIJRXWWQK-UHFFFAOYSA-N Cyclopentenone Chemical class O=C1CCC=C1 BZKFMUIJRXWWQK-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 229910000080 stannane Inorganic materials 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/08—Copper compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/649,402 US5684177A (en) | 1996-05-17 | 1996-05-17 | Misoprostol |
| CA002176763A CA2176763C (en) | 1996-05-17 | 1996-05-17 | Misoprostol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE236907T1 true ATE236907T1 (de) | 2003-04-15 |
Family
ID=25678471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97303062T ATE236907T1 (de) | 1996-05-17 | 1997-05-06 | Misoprostol, verfahren zur deren herstellung mit verwendung eines organometall-kupferkomplexes |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0807634B1 (de) |
| AT (1) | ATE236907T1 (de) |
| DE (1) | DE69720587D1 (de) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4087621A (en) * | 1974-03-26 | 1978-05-02 | G. D. Searle & Co. | 7-{3-Hydroxy-2β-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-oxocyclopent-1α-yl}hept-5-cis-enoic acids and related compounds |
| US3965143A (en) * | 1974-03-26 | 1976-06-22 | G. D. Searle & Co. | 16-Oxygenated prostanoic acid derivatives |
| US4904820A (en) * | 1987-06-09 | 1990-02-27 | G. D. Searle & Co. | Process for substituting a hydrocarbon group |
-
1997
- 1997-05-06 AT AT97303062T patent/ATE236907T1/de not_active IP Right Cessation
- 1997-05-06 DE DE69720587T patent/DE69720587D1/de not_active Expired - Lifetime
- 1997-05-06 EP EP97303062A patent/EP0807634B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0807634A3 (de) | 1998-10-21 |
| DE69720587D1 (de) | 2003-05-15 |
| EP0807634A2 (de) | 1997-11-19 |
| EP0807634B1 (de) | 2003-04-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |