ATE231845T1 - 1,2,4-triazinderivate zur inhibierung der proteinglycosylierung - Google Patents
1,2,4-triazinderivate zur inhibierung der proteinglycosylierungInfo
- Publication number
- ATE231845T1 ATE231845T1 AT97919945T AT97919945T ATE231845T1 AT E231845 T1 ATE231845 T1 AT E231845T1 AT 97919945 T AT97919945 T AT 97919945T AT 97919945 T AT97919945 T AT 97919945T AT E231845 T1 ATE231845 T1 AT E231845T1
- Authority
- AT
- Austria
- Prior art keywords
- triazine derivatives
- inhibiting
- inhibiting protein
- protein glycosylation
- composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62304596A | 1996-03-28 | 1996-03-28 | |
US64324296A | 1996-05-03 | 1996-05-03 | |
US08/825,114 US5932578A (en) | 1996-03-28 | 1997-03-27 | Triazine compounds and methods of use therefor |
PCT/US1997/005110 WO1997035849A1 (en) | 1996-03-28 | 1997-03-28 | 1,2,4-triazine derivatives for the inhibition of protein glycosylation |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE231845T1 true ATE231845T1 (de) | 2003-02-15 |
Family
ID=27417336
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97919945T ATE231845T1 (de) | 1996-03-28 | 1997-03-28 | 1,2,4-triazinderivate zur inhibierung der proteinglycosylierung |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0889884B1 (de) |
JP (1) | JP2002515870A (de) |
AT (1) | ATE231845T1 (de) |
AU (1) | AU727846B2 (de) |
CA (1) | CA2249999A1 (de) |
DE (1) | DE69718775T2 (de) |
ES (1) | ES2191837T3 (de) |
WO (1) | WO1997035849A1 (de) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4036632A (en) * | 1966-04-16 | 1977-07-19 | Bayer Aktiengesellschaft | Herbicidal agents |
US5114943A (en) * | 1984-03-19 | 1992-05-19 | The Rockefeller University | Amino-substituted pyrimidines, derivatives and methods of use therefor |
US5399560A (en) * | 1984-03-19 | 1995-03-21 | The Rockefeller University | 1,2,4-triazine products resulting from the inhibition of advanced glycosylation |
-
1997
- 1997-03-28 JP JP53385697A patent/JP2002515870A/ja not_active Ceased
- 1997-03-28 AT AT97919945T patent/ATE231845T1/de not_active IP Right Cessation
- 1997-03-28 CA CA002249999A patent/CA2249999A1/en not_active Abandoned
- 1997-03-28 DE DE69718775T patent/DE69718775T2/de not_active Expired - Fee Related
- 1997-03-28 AU AU24254/97A patent/AU727846B2/en not_active Ceased
- 1997-03-28 EP EP97919945A patent/EP0889884B1/de not_active Expired - Lifetime
- 1997-03-28 WO PCT/US1997/005110 patent/WO1997035849A1/en active IP Right Grant
- 1997-03-28 ES ES97919945T patent/ES2191837T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU2425497A (en) | 1997-10-17 |
ES2191837T3 (es) | 2003-09-16 |
WO1997035849A1 (en) | 1997-10-02 |
EP0889884B1 (de) | 2003-01-29 |
CA2249999A1 (en) | 1997-10-02 |
JP2002515870A (ja) | 2002-05-28 |
AU727846B2 (en) | 2001-01-04 |
EP0889884A1 (de) | 1999-01-13 |
DE69718775D1 (de) | 2003-03-06 |
DE69718775T2 (de) | 2003-10-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |