ATE218858T1 - C9 taxanderivate und diese enthaltende pharmazeutische zusammensetzungen - Google Patents

C9 taxanderivate und diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number
ATE218858T1
ATE218858T1 AT94909840T AT94909840T ATE218858T1 AT E218858 T1 ATE218858 T1 AT E218858T1 AT 94909840 T AT94909840 T AT 94909840T AT 94909840 T AT94909840 T AT 94909840T AT E218858 T1 ATE218858 T1 AT E218858T1
Authority
AT
Austria
Prior art keywords
pharmaceutical compositions
compositions containing
containing same
taxan derivatives
derivatives
Prior art date
Application number
AT94909840T
Other languages
English (en)
Inventor
Robert A Holton
Ki-Byung Chai
Yukio Suzuki
Original Assignee
Univ Florida State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/026,978 external-priority patent/US5990325A/en
Application filed by Univ Florida State filed Critical Univ Florida State
Application granted granted Critical
Publication of ATE218858T1 publication Critical patent/ATE218858T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT94909840T 1993-03-05 1994-03-01 C9 taxanderivate und diese enthaltende pharmazeutische zusammensetzungen ATE218858T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/026,978 US5990325A (en) 1993-03-05 1993-03-05 Process for the preparation of 9-desoxotaxol, 9-desoxobaccatin III and analogs thereof
US3485293A 1993-03-22 1993-03-22
US9508793A 1993-07-20 1993-07-20
PCT/US1994/002210 WO1994020088A1 (en) 1993-03-05 1994-03-01 C9 taxane derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
ATE218858T1 true ATE218858T1 (de) 2002-06-15

Family

ID=27362899

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94909840T ATE218858T1 (de) 1993-03-05 1994-03-01 C9 taxanderivate und diese enthaltende pharmazeutische zusammensetzungen

Country Status (10)

Country Link
EP (2) EP0688212B1 (de)
JP (1) JP3892480B2 (de)
AT (1) ATE218858T1 (de)
AU (1) AU686137B2 (de)
DE (1) DE69430797T2 (de)
DK (1) DK0688212T3 (de)
ES (1) ES2179070T3 (de)
IL (1) IL108836A (de)
PT (1) PT688212E (de)
WO (1) WO1994020088A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5710287A (en) 1991-09-23 1998-01-20 Florida State University Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
US5677470A (en) * 1994-06-28 1997-10-14 Tanabe Seiyaku Co., Ltd. Baccatin derivatives and processes for preparing the same
CA2162759A1 (en) * 1994-11-17 1996-05-18 Kenji Tsujihara Baccatin derivatives and processes for preparing the same
ATE377593T1 (de) 2003-09-25 2007-11-15 Tapestry Pharmaceuticals Inc 9,10-alpha,alpha-oh-taxananaloga und verfahren zu deren herstellung
EP1810968A3 (de) * 2003-09-25 2007-08-08 Tapestry Pharmaceuticals, Inc. 9, 10-a, a-OH-Taxan-Analoge und Herstellungsverfahren dafür
CN100516067C (zh) 2006-01-10 2009-07-22 上海恒瑞医药有限公司 具有抗肿瘤活性的紫杉酚衍生物
US11786504B2 (en) 2006-09-28 2023-10-17 Tapestry Pharmaceuticals, Inc. Taxane analogs for the treatment of brain cancer
WO2008106621A1 (en) 2007-02-28 2008-09-04 Tapestry Pharmaceuticals, Inc Taxane analogs for the treatment of brain cancer
WO2008121476A1 (en) 2007-03-28 2008-10-09 Tapestry Pharmaceuticals, Inc. Biologically active taxane analogs and methods of treatment by oral administration
US11873308B2 (en) 2006-11-06 2024-01-16 Tapestry Pharmaceuticals, Inc. Biologically active taxane analogs and methods of treatment by oral administration

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4942184A (en) * 1988-03-07 1990-07-17 The United States Of America As Represented By The Department Of Health And Human Services Water soluble, antineoplastic derivatives of taxol
US4960790A (en) * 1989-03-09 1990-10-02 University Of Kansas Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam

Also Published As

Publication number Publication date
EP0688212B1 (de) 2002-06-12
EP0688212A1 (de) 1995-12-27
ES2179070T3 (es) 2003-01-16
MX9401623A (es) 1997-09-30
DE69430797T2 (de) 2003-02-27
DE69430797D1 (de) 2002-07-18
JPH08507309A (ja) 1996-08-06
AU686137B2 (en) 1998-02-05
JP3892480B2 (ja) 2007-03-14
WO1994020088A1 (en) 1994-09-15
IL108836A0 (en) 1994-06-24
EP0688212A4 (de) 1996-03-20
EP1148055A1 (de) 2001-10-24
AU6252594A (en) 1994-09-26
PT688212E (pt) 2002-11-29
DK0688212T3 (da) 2002-10-07
IL108836A (en) 2005-11-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee