ATE214921T1 - Neuer kalium-kanal-agonist, der von trichoderma virens gewonnen wird - Google Patents
Neuer kalium-kanal-agonist, der von trichoderma virens gewonnen wirdInfo
- Publication number
- ATE214921T1 ATE214921T1 AT95905401T AT95905401T ATE214921T1 AT E214921 T1 ATE214921 T1 AT E214921T1 AT 95905401 T AT95905401 T AT 95905401T AT 95905401 T AT95905401 T AT 95905401T AT E214921 T1 ATE214921 T1 AT E214921T1
- Authority
- AT
- Austria
- Prior art keywords
- potassium channel
- channel agonist
- trichoderma virens
- new potassium
- agonist derived
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/166,499 US5399587A (en) | 1993-12-13 | 1993-12-13 | Biologically active compounds |
PCT/US1994/014491 WO1995016442A1 (en) | 1993-12-13 | 1994-12-09 | Novel potassium channel agonist produced from trichoderma virens |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE214921T1 true ATE214921T1 (de) | 2002-04-15 |
Family
ID=22603577
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95905401T ATE214921T1 (de) | 1993-12-13 | 1994-12-09 | Neuer kalium-kanal-agonist, der von trichoderma virens gewonnen wird |
Country Status (8)
Country | Link |
---|---|
US (1) | US5399587A (de) |
EP (1) | EP0734255B1 (de) |
JP (1) | JPH09506627A (de) |
AT (1) | ATE214921T1 (de) |
AU (1) | AU689193B2 (de) |
CA (1) | CA2179068A1 (de) |
DE (1) | DE69430259D1 (de) |
WO (1) | WO1995016442A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050153940A1 (en) * | 2000-01-26 | 2005-07-14 | Cedars-Sinai Medical Center | Method for using potassium channel activation for delivering a medicant to an abnormal brain region and/or a malignant tumor |
US7018979B1 (en) | 2000-01-26 | 2006-03-28 | Cedars-Sinai Medical Center | Method for using potassium channel agonists for delivering a medicant to an abnormal brain region and/or a malignant tumor |
US7211561B2 (en) * | 2001-10-12 | 2007-05-01 | Cedars-Sinai Medical Center | Method for inducing selective cell death of malignant cells by activation of calcium-activated potassium channels (KCa) |
EP1850852A4 (de) * | 2005-02-22 | 2009-11-18 | Cedars Sinai Medical Center | Verwendung von sildenafil, vardenafil und anderen 5-phosphodiesterase-hemmern zur erhöhung der durchlässigkeit der abnormalen blut-hirn-schranke |
CN108640832B (zh) * | 2018-04-23 | 2020-10-09 | 中国科学院烟台海岸带研究所 | 一种杜松烷倍半萜类化合物及其制备和应用 |
CN108373457B (zh) * | 2018-04-23 | 2021-04-06 | 中国科学院烟台海岸带研究所 | 一种环氧倍半萜类化合物及其制备和应用 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61130250A (ja) * | 1984-11-30 | 1986-06-18 | Taisho Pharmaceut Co Ltd | 抗生物質caf−0603 |
US4831033A (en) * | 1987-04-16 | 1989-05-16 | City Of Hope | Use of amodiaquin in treatment of nervous system degeneration |
EP0310410A3 (de) * | 1987-10-02 | 1990-01-17 | Kawate, Tsuneyoshi | Kalziumbeschleunigte Kalium-Flut-Kontrolle von geschädigten Körperzellen |
US5006512A (en) * | 1987-10-02 | 1991-04-09 | Tsuyoshi Ohnishi | Therapeutic usages of inhibitors for a potassium efflux channel |
US4929718A (en) * | 1987-12-14 | 1990-05-29 | Universidad Nacional Autonoma De Mexico | Synthetic noxiustoxin related peptides |
EP0408650A1 (de) * | 1988-04-08 | 1991-01-23 | Massachusetts Institute Of Technology | Verfahren und zusammensetzung für die behandlung neurologischer störungen |
DE3825561A1 (de) * | 1988-07-28 | 1990-02-01 | Basf Ag | P-hydroxiphenon-derivate und diese enthaltende arzneimittel |
US5006523A (en) * | 1989-10-26 | 1991-04-09 | E. R. Squibb & Sons, Inc. | Antiarrhythmic agents: aryl cyanoguanidine potassium channel blockers |
US5112824A (en) * | 1989-12-08 | 1992-05-12 | Merck & Co., Inc. | Benzofuran compounds as class III antiarrhythmic agents |
GB9005318D0 (en) * | 1990-03-09 | 1990-05-02 | Isis Innovation | Antiarrhythmic agents |
CA2044853C (en) * | 1990-07-19 | 2004-11-09 | Susan A. Greenfield | Method for treating parkinson's disease employing an atp-sensitive potassium channel blocker |
CA2044855A1 (en) * | 1990-07-20 | 1992-01-21 | Kerry P. S. J. Murphy | Method for treating insult to neurons prone to parkinson's degeneration employing an atp-sensitive potassium channel blocker |
GB9020128D0 (en) * | 1990-09-14 | 1990-10-24 | Reckitt & Colmann Prod Ltd | Imidazoline derivatives |
US5158969A (en) * | 1991-08-21 | 1992-10-27 | Neurosearch A/S | Indole derivatives as potassium channel blockers |
-
1993
- 1993-12-13 US US08/166,499 patent/US5399587A/en not_active Expired - Fee Related
-
1994
- 1994-12-09 AT AT95905401T patent/ATE214921T1/de not_active IP Right Cessation
- 1994-12-09 JP JP7516957A patent/JPH09506627A/ja active Pending
- 1994-12-09 DE DE69430259T patent/DE69430259D1/de not_active Expired - Lifetime
- 1994-12-09 EP EP95905401A patent/EP0734255B1/de not_active Expired - Lifetime
- 1994-12-09 AU AU14026/95A patent/AU689193B2/en not_active Ceased
- 1994-12-09 WO PCT/US1994/014491 patent/WO1995016442A1/en active IP Right Grant
- 1994-12-09 CA CA002179068A patent/CA2179068A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2179068A1 (en) | 1995-06-22 |
US5399587A (en) | 1995-03-21 |
EP0734255A1 (de) | 1996-10-02 |
AU689193B2 (en) | 1998-03-26 |
DE69430259D1 (de) | 2002-05-02 |
JPH09506627A (ja) | 1997-06-30 |
WO1995016442A1 (en) | 1995-06-22 |
EP0734255B1 (de) | 2002-03-27 |
AU1402695A (en) | 1995-07-03 |
EP0734255A4 (de) | 1997-04-02 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |