ATE211654T1 - Antigene des hybriden m-proteins und träger für gruppe a streptokokkenimpfstoff - Google Patents
Antigene des hybriden m-proteins und träger für gruppe a streptokokkenimpfstoffInfo
- Publication number
- ATE211654T1 ATE211654T1 AT93922202T AT93922202T ATE211654T1 AT E211654 T1 ATE211654 T1 AT E211654T1 AT 93922202 T AT93922202 T AT 93922202T AT 93922202 T AT93922202 T AT 93922202T AT E211654 T1 ATE211654 T1 AT E211654T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- antigens
- protein
- hybrid
- carriers
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 229940124840 Streptococcal vaccine Drugs 0.000 title 1
- 239000000969 carrier Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 241001505901 Streptococcus sp. 'group A' Species 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000036039 immunity Effects 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 201000003068 rheumatic fever Diseases 0.000 abstract 1
- 108010010318 streptococcal M protein Proteins 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/807—Hapten conjugated with peptide or protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94586092A | 1992-09-16 | 1992-09-16 | |
PCT/US1993/008704 WO1994006465A1 (en) | 1992-09-16 | 1993-09-15 | Antigen of hybrid m protein and carrier for group a streptococcal vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE211654T1 true ATE211654T1 (de) | 2002-01-15 |
Family
ID=25483630
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT93922202T ATE211654T1 (de) | 1992-09-16 | 1993-09-15 | Antigene des hybriden m-proteins und träger für gruppe a streptokokkenimpfstoff |
Country Status (9)
Country | Link |
---|---|
US (3) | US6419932B1 (de) |
EP (1) | EP0618813B1 (de) |
AT (1) | ATE211654T1 (de) |
AU (1) | AU5128593A (de) |
CA (1) | CA2123580C (de) |
DE (1) | DE69331437T2 (de) |
DK (1) | DK0618813T3 (de) |
IL (1) | IL107026A0 (de) |
WO (1) | WO1994006465A1 (de) |
Families Citing this family (88)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6737521B1 (en) * | 1990-05-11 | 2004-05-18 | The Rockefeller University | Delivery and expression of a hybrid surface protein on the surface of gram positive bacteria |
DK0618813T3 (da) * | 1992-09-16 | 2002-03-11 | Univ Tennessee Res Corp | Antigen for M-hybridprotein og bærer for gruppe A streptococcal vaccine |
AUPM885194A0 (en) * | 1994-10-14 | 1994-11-10 | Council Of The Queensland Institute Of Medical Research, The | Synthetic peptides and vaccines comprising same |
NZ297142A (en) * | 1994-10-24 | 2001-09-28 | Texas A & M Univ Sys | Oral immunisation and oral vaccines using edible transgenic plants comprising immunogenic agents such as E coli and cholera toxin antigens |
US6287574B1 (en) * | 1995-03-17 | 2001-09-11 | Biochem Pharma Inc. | Proteinase K resistant surface protein of neisseria meningitidis |
US5846547A (en) | 1996-01-22 | 1998-12-08 | Regents Of The University Of Minnesota | Streptococcal C5a peptidase vaccine |
US6355255B1 (en) | 1998-12-07 | 2002-03-12 | Regents Of The University Of Minnesota | Streptococcal C5a peptidase vaccine |
US5882896A (en) * | 1996-09-24 | 1999-03-16 | Smithkline Beecham Corporation | M protein |
US20110166040A1 (en) * | 1997-09-05 | 2011-07-07 | Ibis Biosciences, Inc. | Compositions for use in identification of strains of e. coli o157:h7 |
US6716433B1 (en) | 1997-09-12 | 2004-04-06 | University Of Tennessee Research Foundation | Group a streptococcal vaccines |
EP1801217A1 (de) * | 1997-09-12 | 2007-06-27 | The University of Tennessee Research Foundation | Streptokokken-Impfstoffgruppe |
CA2353802C (en) * | 1998-12-22 | 2013-10-01 | The University Of Tennessee Research Corporation | New protective antigen of group a streptococci |
US7063850B1 (en) | 1998-12-22 | 2006-06-20 | University Of Tennessee Research Foundation | Protective antigen of group A Streptococci |
EP1163000B1 (de) * | 1999-03-19 | 2008-02-27 | GlaxoSmithKline Biologicals S.A. | Impfstoff gegen bakterielle antigene |
US7256265B2 (en) | 1999-12-03 | 2007-08-14 | Regents Of The University Of Minnesota | Streptococcal C5a peptidase vaccine |
GB0022742D0 (en) * | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
GB0025170D0 (en) * | 2000-10-13 | 2000-11-29 | Smithkline Beecham Biolog | Novel compounds |
WO2004060278A2 (en) | 2002-12-06 | 2004-07-22 | Isis Pharmaceuticals, Inc. | Methods for rapid identification of pathogens in humans and animals |
US7718354B2 (en) | 2001-03-02 | 2010-05-18 | Ibis Biosciences, Inc. | Methods for rapid identification of pathogens in humans and animals |
US7226739B2 (en) | 2001-03-02 | 2007-06-05 | Isis Pharmaceuticals, Inc | Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations |
US20040121335A1 (en) | 2002-12-06 | 2004-06-24 | Ecker David J. | Methods for rapid detection and identification of bioagents associated with host versus graft and graft versus host rejections |
US20030027135A1 (en) | 2001-03-02 | 2003-02-06 | Ecker David J. | Method for rapid detection and identification of bioagents |
US7666588B2 (en) | 2001-03-02 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy |
CA2447017A1 (en) * | 2001-05-15 | 2002-11-21 | Shire Biochem Inc. | Moraxella(branhamella) catarrhalis antigens |
US7407664B2 (en) | 2001-05-18 | 2008-08-05 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Peptide vaccines against group A streptococci |
US8073627B2 (en) | 2001-06-26 | 2011-12-06 | Ibis Biosciences, Inc. | System for indentification of pathogens |
US7217510B2 (en) | 2001-06-26 | 2007-05-15 | Isis Pharmaceuticals, Inc. | Methods for providing bacterial bioagent characterizing information |
CA2453062C (en) | 2001-07-06 | 2013-04-02 | Shire Biochem Inc. | Group b streptococcus bvh-a5 antigens and corresponding dna fragments |
CA2464527A1 (en) * | 2001-10-26 | 2003-08-14 | Id Biomedical Corporation Of Washington | Multivalent streptococcal vaccine compositions and methods for use |
US7255867B2 (en) * | 2002-11-15 | 2007-08-14 | Id Biomedical Corporation Of Quebec | Vaccine |
US20040151737A1 (en) * | 2003-02-05 | 2004-08-05 | University Of Tennessee | Streptococcal serum opacity factors and fibronectin-binding proteins and peptides thereof for the treatment and detection of streptococcal infection |
US8046171B2 (en) | 2003-04-18 | 2011-10-25 | Ibis Biosciences, Inc. | Methods and apparatus for genetic evaluation |
US8057993B2 (en) | 2003-04-26 | 2011-11-15 | Ibis Biosciences, Inc. | Methods for identification of coronaviruses |
US7964343B2 (en) | 2003-05-13 | 2011-06-21 | Ibis Biosciences, Inc. | Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture |
US8158354B2 (en) | 2003-05-13 | 2012-04-17 | Ibis Biosciences, Inc. | Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture |
US7709009B2 (en) | 2003-07-31 | 2010-05-04 | Novartis Vaccines And Diagnostics, Srl | Immunogenic compositions for streptococcus pyogenes |
WO2005017093A2 (en) * | 2003-08-15 | 2005-02-24 | Id Biomedical Corporation | Polypeptides of streptococcus pyogenes |
US8097416B2 (en) | 2003-09-11 | 2012-01-17 | Ibis Biosciences, Inc. | Methods for identification of sepsis-causing bacteria |
US8546082B2 (en) | 2003-09-11 | 2013-10-01 | Ibis Biosciences, Inc. | Methods for identification of sepsis-causing bacteria |
US20100129811A1 (en) * | 2003-09-11 | 2010-05-27 | Ibis Biosciences, Inc. | Compositions for use in identification of pseudomonas aeruginosa |
US20120122096A1 (en) | 2003-09-11 | 2012-05-17 | Rangarajan Sampath | Compositions for use in identification of bacteria |
US8163895B2 (en) | 2003-12-05 | 2012-04-24 | Ibis Biosciences, Inc. | Compositions for use in identification of orthopoxviruses |
US7666592B2 (en) | 2004-02-18 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for concurrent identification and quantification of an unknown bioagent |
US8119336B2 (en) | 2004-03-03 | 2012-02-21 | Ibis Biosciences, Inc. | Compositions for use in identification of alphaviruses |
EP2458619B1 (de) | 2004-05-24 | 2017-08-02 | Ibis Biosciences, Inc. | Massenspektrometrie mit selektivem Ionfilter durch digitale Schwelle |
US20050266411A1 (en) | 2004-05-25 | 2005-12-01 | Hofstadler Steven A | Methods for rapid forensic analysis of mitochondrial DNA |
US7811753B2 (en) | 2004-07-14 | 2010-10-12 | Ibis Biosciences, Inc. | Methods for repairing degraded DNA |
US8084207B2 (en) | 2005-03-03 | 2011-12-27 | Ibis Bioscience, Inc. | Compositions for use in identification of papillomavirus |
WO2006094238A2 (en) | 2005-03-03 | 2006-09-08 | Isis Pharmaceuticals, Inc. | Compositions for use in identification of adventitious viruses |
WO2007014045A2 (en) | 2005-07-21 | 2007-02-01 | Isis Pharmaceuticals, Inc. | Methods for rapid identification and quantitation of nucleic acid variants |
EP1931779A4 (de) | 2005-10-04 | 2009-07-29 | Inimex Pharmaceuticals Inc | Neue peptide zur behandlung und vorbeugung immunverwandter störungen, einschliesslich behandlung und vorbeugung durch modulation angeborener immunität |
WO2007118222A2 (en) | 2006-04-06 | 2007-10-18 | Ibis Biosciences, INC | Compositions for the use in identification of fungi |
WO2008143627A2 (en) | 2006-09-14 | 2008-11-27 | Ibis Biosciences, Inc. | Targeted whole genome amplification method for identification of pathogens |
JP2010505395A (ja) * | 2006-10-04 | 2010-02-25 | イニメックス ファーマシューティカルズ インコーポレイテッド | 先天免疫を調節することによる感染の処置および予防を含む、免疫関連疾患障害の処置および予防のための新規ペプチド |
BRPI0604997A (pt) | 2006-11-30 | 2007-05-22 | Fundacao Zerbini | vacina contra o estreptococo beta hemolìtico do grupo a, e respectivo processo de obtenção |
US9289485B2 (en) | 2006-11-30 | 2016-03-22 | Luiza Guilherme Guglielmi | Therapeutic application of S. pyogenes C-terminal peptide |
US8871471B2 (en) | 2007-02-23 | 2014-10-28 | Ibis Biosciences, Inc. | Methods for rapid forensic DNA analysis |
US20100291544A1 (en) * | 2007-05-25 | 2010-11-18 | Ibis Biosciences, Inc. | Compositions for use in identification of strains of hepatitis c virus |
WO2008151023A2 (en) | 2007-06-01 | 2008-12-11 | Ibis Biosciences, Inc. | Methods and compositions for multiple displacement amplification of nucleic acids |
WO2009038840A2 (en) * | 2007-06-14 | 2009-03-26 | Ibis Biosciences, Inc. | Compositions for use in identification of adventitious contaminant viruses |
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US20110151437A1 (en) * | 2008-06-02 | 2011-06-23 | Ibis Biosciences, Inc. | Compositions for use in identification of adventitious viruses |
US8550694B2 (en) | 2008-09-16 | 2013-10-08 | Ibis Biosciences, Inc. | Mixing cartridges, mixing stations, and related kits, systems, and methods |
EP2344893B1 (de) | 2008-09-16 | 2014-10-15 | Ibis Biosciences, Inc. | Mikroplatten-handhabungssysteme und verfahren |
US8148163B2 (en) | 2008-09-16 | 2012-04-03 | Ibis Biosciences, Inc. | Sample processing units, systems, and related methods |
US20110200985A1 (en) * | 2008-10-02 | 2011-08-18 | Rangarajan Sampath | Compositions for use in identification of herpesviruses |
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WO2010039848A2 (en) * | 2008-10-03 | 2010-04-08 | Ibis Biosciences, Inc. | Compositions for use in identification of streptococcus pneumoniae |
US20110183344A1 (en) * | 2008-10-03 | 2011-07-28 | Rangarajan Sampath | Compositions for use in identification of clostridium difficile |
US20110190170A1 (en) * | 2008-10-03 | 2011-08-04 | Ibis Biosciences, Inc. | Compositions for use in identification of antibiotic-resistant bacteria |
WO2010039870A1 (en) * | 2008-10-03 | 2010-04-08 | Ibis Biosciences, Inc. | Compositions for use in identification of neisseria, chlamydia, and/or chlamydophila bacteria |
US20110183343A1 (en) * | 2008-10-03 | 2011-07-28 | Rangarajan Sampath | Compositions for use in identification of members of the bacterial class alphaproteobacter |
EP2356135B1 (de) | 2008-11-05 | 2017-10-25 | Wyeth LLC | Immunogene multikomponentenzusammensetzung zur prävention einer erkrankung mit beta-hämolytischen streptokokken (bhs) |
EP2396803A4 (de) | 2009-02-12 | 2016-10-26 | Ibis Biosciences Inc | Ionisationssondenanordnungen |
WO2010104798A1 (en) | 2009-03-08 | 2010-09-16 | Ibis Biosciences, Inc. | Bioagent detection methods |
WO2010114842A1 (en) | 2009-03-30 | 2010-10-07 | Ibis Biosciences, Inc. | Bioagent detection systems, devices, and methods |
WO2011008971A1 (en) | 2009-07-17 | 2011-01-20 | Ibis Biosciences, Inc. | Lift and mount apparatus |
US9194877B2 (en) | 2009-07-17 | 2015-11-24 | Ibis Biosciences, Inc. | Systems for bioagent indentification |
WO2011014811A1 (en) | 2009-07-31 | 2011-02-03 | Ibis Biosciences, Inc. | Capture primers and capture sequence linked solid supports for molecular diagnostic tests |
EP3098325A1 (de) | 2009-08-06 | 2016-11-30 | Ibis Biosciences, Inc. | Basenzusammensetzungen ohne massenbestimmung zur nukleinsäureerkennung |
US20110065111A1 (en) * | 2009-08-31 | 2011-03-17 | Ibis Biosciences, Inc. | Compositions For Use In Genotyping Of Klebsiella Pneumoniae |
US9890408B2 (en) | 2009-10-15 | 2018-02-13 | Ibis Biosciences, Inc. | Multiple displacement amplification |
WO2011115840A2 (en) * | 2010-03-14 | 2011-09-22 | Ibis Biosciences, Inc. | Parasite detection via endosymbiont detection |
EP2720706B1 (de) | 2011-06-17 | 2020-08-05 | University of Tennessee Research Foundation | Polyvalenter streptococcus-gruppe-a-impfstoff |
AU2014214613A1 (en) | 2013-02-11 | 2015-08-13 | University Of Tennessee Research Foundation | Group A streptococcal M-related proteins and methods of use |
CL2013002782A1 (es) * | 2013-09-27 | 2014-04-25 | Univ Pontificia Catolica Chile | Formulación inmunogénica para inducir la respuesta inmune en un sujeto que comprende una mezcla de bacterias no patógenas que expresan cada una un segmento hipervariable de la proteína m de diferentes streptococcus pyogenes; uso de la formulación para producir una vacuna; método para producir vacuna |
Family Cites Families (23)
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CA1200773A (en) * | 1980-02-29 | 1986-02-18 | William J. Rutter | Expression linkers |
US4284537A (en) * | 1980-07-03 | 1981-08-18 | The United States Of America As Represented By The Department Of Health And Human Services | Conjugate of streptococcal M protein peptide vaccine |
US4521334A (en) | 1982-07-27 | 1985-06-04 | The University Of Tennesse Research Corporation | Synthetic polypeptide fragments |
US4454121A (en) | 1982-07-27 | 1984-06-12 | The University Of Tennessee Research Corporation | Synthetic peptides corresponding to antigenic determinants of the M protein of Streptococcus pyogenes |
US4597967A (en) | 1982-07-27 | 1986-07-01 | The University Of Tennessee Research Corp. | Synthetic polypeptide fragments |
US4886663A (en) * | 1983-01-03 | 1989-12-12 | Scripps Clinic And Research Foundation | Synthetic heat-stable enterotoxin polypeptide of Escherichia coli and multimers thereof |
US4919930A (en) * | 1983-06-10 | 1990-04-24 | University Of Tennessee Research Corporation | Synthetic M proteins-streptococci type 5 |
US4784948A (en) * | 1983-08-10 | 1988-11-15 | The Rockefeller University | Production of streptococcal m protein immunogens and molecular probes |
US5149657A (en) * | 1984-09-13 | 1992-09-22 | Enzon Labs Inc. | Escherichia coli expression vector encoding bioadhesive precursor protein analogs comprising three to twenty repeats of the decapeptide (Ala-Lys-Pro-Ser-Tyr-Pro-Pro-Thr-Tyr-Lys) |
US4705684A (en) | 1985-05-31 | 1987-11-10 | The University Of Tennessee Research Corporation | Synthetic M proteins - streptococci type 6 |
US5124153A (en) * | 1987-08-24 | 1992-06-23 | University Of Tennessee Research Corp. | Therapeutic compositions against streptococcal infections, transformed hosts, methods of immunization and genetically engineered products |
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WO1993021220A1 (en) * | 1992-04-08 | 1993-10-28 | The Council Of The Queensland Institute Of Medical Research | Synthetic peptides useful in a vaccine against and in the diagnosis of streptococcal infection |
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ATE348175T1 (de) * | 1992-07-17 | 2007-01-15 | Dana Farber Cancer Inst Inc | Method eder intrazellularen bindung von zielgerichteten molekülen |
DK0618813T3 (da) * | 1992-09-16 | 2002-03-11 | Univ Tennessee Res Corp | Antigen for M-hybridprotein og bærer for gruppe A streptococcal vaccine |
ATE214601T1 (de) * | 1992-09-16 | 2002-04-15 | Univ Tennessee Res Corp | Rekombinantes vielwertiges m-protein-vakzin |
US5763733A (en) * | 1994-10-13 | 1998-06-09 | Enzon, Inc. | Antigen-binding fusion proteins |
US6716433B1 (en) * | 1997-09-12 | 2004-04-06 | University Of Tennessee Research Foundation | Group a streptococcal vaccines |
CA2464527A1 (en) * | 2001-10-26 | 2003-08-14 | Id Biomedical Corporation Of Washington | Multivalent streptococcal vaccine compositions and methods for use |
-
1993
- 1993-09-15 DK DK93922202T patent/DK0618813T3/da active
- 1993-09-15 DE DE69331437T patent/DE69331437T2/de not_active Expired - Fee Related
- 1993-09-15 WO PCT/US1993/008704 patent/WO1994006465A1/en active IP Right Grant
- 1993-09-15 CA CA002123580A patent/CA2123580C/en not_active Expired - Fee Related
- 1993-09-15 IL IL107026A patent/IL107026A0/xx unknown
- 1993-09-15 AU AU51285/93A patent/AU5128593A/en not_active Abandoned
- 1993-09-15 AT AT93922202T patent/ATE211654T1/de not_active IP Right Cessation
- 1993-09-15 EP EP93922202A patent/EP0618813B1/de not_active Expired - Lifetime
-
1997
- 1997-08-19 US US08/914,479 patent/US6419932B1/en not_active Expired - Fee Related
-
2002
- 2002-05-07 US US10/141,627 patent/US7074416B2/en not_active Expired - Fee Related
-
2006
- 2006-05-01 US US11/415,382 patent/US20070053937A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2123580A1 (en) | 1994-03-21 |
EP0618813A4 (en) | 1997-05-21 |
EP0618813B1 (de) | 2002-01-09 |
US20070053937A1 (en) | 2007-03-08 |
US6419932B1 (en) | 2002-07-16 |
CA2123580C (en) | 2005-04-26 |
DE69331437T2 (de) | 2002-09-05 |
WO1994006465A1 (en) | 1994-03-31 |
US20020176863A1 (en) | 2002-11-28 |
IL107026A0 (en) | 1993-12-28 |
EP0618813A1 (de) | 1994-10-12 |
DK0618813T3 (da) | 2002-03-11 |
AU5128593A (en) | 1994-04-12 |
DE69331437D1 (de) | 2002-02-14 |
US7074416B2 (en) | 2006-07-11 |
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