ATE207485T1 - Ein triazolylmethyl-indol-ethylamin-bisulfat-salz - Google Patents

Ein triazolylmethyl-indol-ethylamin-bisulfat-salz

Info

Publication number
ATE207485T1
ATE207485T1 AT96925277T AT96925277T ATE207485T1 AT E207485 T1 ATE207485 T1 AT E207485T1 AT 96925277 T AT96925277 T AT 96925277T AT 96925277 T AT96925277 T AT 96925277T AT E207485 T1 ATE207485 T1 AT E207485T1
Authority
AT
Austria
Prior art keywords
ethylamin
triazolylmethyl
indole
bisulphate salt
salt
Prior art date
Application number
AT96925277T
Other languages
English (en)
Inventor
Chen Y Cheng
Robert D Larsen
James A Mccauley
Jennifer L Vandrilla
Thomas R Verhoeven
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9602977.2A external-priority patent/GB9602977D0/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE207485T1 publication Critical patent/ATE207485T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT96925277T 1995-07-11 1996-07-08 Ein triazolylmethyl-indol-ethylamin-bisulfat-salz ATE207485T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US105595P 1995-07-11 1995-07-11
GBGB9602977.2A GB9602977D0 (en) 1996-02-13 1996-02-13 A triazolylmethyl-indole ethylamine bisulfate salt
PCT/US1996/011370 WO1997003068A1 (en) 1995-07-11 1996-07-08 A triazolylmethyl-indole ethylamine bisulfate salt

Publications (1)

Publication Number Publication Date
ATE207485T1 true ATE207485T1 (de) 2001-11-15

Family

ID=26308694

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96925277T ATE207485T1 (de) 1995-07-11 1996-07-08 Ein triazolylmethyl-indol-ethylamin-bisulfat-salz

Country Status (8)

Country Link
EP (1) EP0840733B1 (de)
JP (1) JPH11508916A (de)
AT (1) ATE207485T1 (de)
AU (1) AU6542896A (de)
CA (1) CA2225416C (de)
DE (1) DE69616335T2 (de)
ES (1) ES2163032T3 (de)
WO (1) WO1997003068A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6231833B1 (en) 1999-08-05 2001-05-15 Pfizer Inc 2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
MXPA04003928A (es) * 2001-10-26 2005-03-31 Dey L P Solucion para inhalacion de albuterol, sistema, equipo y metodo para aliviar sintomas de asma pediatrica.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK278998B6 (sk) * 1991-02-01 1998-05-06 Merck Sharp & Dohme Limited Deriváty imidazolu, triazolu a tetrazolu, spôsob i
DE69318212T2 (de) * 1992-06-05 1998-11-19 Merck Sharp & Dohme Sulfatsalz von einem substituierten Triazol, seine pharmazeutischen Zusammensetzungen und ihre Verwendung in Therapie
US5567824A (en) * 1994-05-24 1996-10-22 Merck & Co., Inc. Palladium catalyzed ring closure of triazolyltryptamine

Also Published As

Publication number Publication date
JPH11508916A (ja) 1999-08-03
DE69616335D1 (de) 2001-11-29
WO1997003068A1 (en) 1997-01-30
CA2225416C (en) 2009-02-24
EP0840733B1 (de) 2001-10-24
DE69616335T2 (de) 2002-07-11
AU6542896A (en) 1997-02-10
EP0840733A1 (de) 1998-05-13
ES2163032T3 (es) 2002-01-16
CA2225416A1 (en) 1997-01-30

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties