ATE2006T1 - Peptidyl-disaccharide mit immunologischer aktivitaet, verfahren zur herstellung und impfstoff. - Google Patents
Peptidyl-disaccharide mit immunologischer aktivitaet, verfahren zur herstellung und impfstoff.Info
- Publication number
- ATE2006T1 ATE2006T1 AT80400566T AT80400566T ATE2006T1 AT E2006 T1 ATE2006 T1 AT E2006T1 AT 80400566 T AT80400566 T AT 80400566T AT 80400566 T AT80400566 T AT 80400566T AT E2006 T1 ATE2006 T1 AT E2006T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted
- alkyl
- benzyl
- phenyl
- stereochemistry
- Prior art date
Links
- 150000002016 disaccharides Chemical class 0.000 title 1
- 230000001900 immune effect Effects 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
- -1 substituted alky Chemical group 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/033,597 US4391800A (en) | 1979-04-27 | 1979-04-27 | Immunologically active peptidyl disaccharides and methods of preparation |
| EP80400566A EP0018901B1 (de) | 1979-04-27 | 1980-04-25 | Peptidyl-Disaccharide mit immunologischer Aktivität, Verfahren zur Herstellung und Impfstoff |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE2006T1 true ATE2006T1 (de) | 1982-12-15 |
Family
ID=21871319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT80400566T ATE2006T1 (de) | 1979-04-27 | 1980-04-25 | Peptidyl-disaccharide mit immunologischer aktivitaet, verfahren zur herstellung und impfstoff. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4391800A (de) |
| EP (1) | EP0018901B1 (de) |
| JP (1) | JPS55145696A (de) |
| AT (1) | ATE2006T1 (de) |
| DE (1) | DE3061322D1 (de) |
| DK (1) | DK177580A (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58198496A (ja) * | 1982-05-14 | 1983-11-18 | Dainippon Pharmaceut Co Ltd | グルコサミニルムラミルペプチド誘導体 |
| US4668661A (en) * | 1984-10-23 | 1987-05-26 | President & Fellows Of Harvard College | Sleep inducing agents |
| GB8519416D0 (en) * | 1985-08-01 | 1985-09-04 | Unilever Plc | Oligosaccharides |
| US4950645A (en) * | 1988-07-08 | 1990-08-21 | Immunotherapeutics, Inc. | Composition for macrophage activation |
| US5416070A (en) * | 1988-07-08 | 1995-05-16 | Immunotherapeutics, Inc. | Composition for macrophage activation |
| US5750665A (en) * | 1995-10-04 | 1998-05-12 | Vosika; Gerald J. | Preparation of glucosaminyl muramic acid derivatives |
| WO2001079268A2 (en) * | 2000-04-18 | 2001-10-25 | Eli Lilly And Company | A glycopeptide and preparation thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2326930A1 (fr) * | 1975-10-09 | 1977-05-06 | Anvar | Agents hydrosolubles depresseurs non specifiques des reponses immunitaires |
| FR2343482A1 (fr) | 1976-03-10 | 1977-10-07 | Anvar | La 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-seryl-d-isoglutamine et medicaments la contenant |
| FR2343483A1 (fr) | 1976-03-10 | 1977-10-07 | Anvar | L'ester methylique de la 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-alanyl-d-isoglutamine et le diester methylique de l'acide 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-alanyl-d-glutamique et medicaments les contenant |
| US4082735A (en) * | 1976-04-26 | 1978-04-04 | Syntex (U.S.A.) Inc. | Novel immunological adjuvant compounds and methods of preparation thereof |
| US4082736A (en) * | 1976-04-26 | 1978-04-04 | Syntex (U.S.A.) Inc. | Novel immunological adjuvant compounds and methods of preparation thereof |
| GB1563561A (en) * | 1976-06-23 | 1980-03-26 | Daiichi Seiyaku Co | Muramyldipeptide derivatives and process for the preparation thereof |
| FR2355505A1 (fr) | 1976-06-24 | 1978-01-20 | Anvar | Nouvel agent adjuvant immunitaire |
| SU727647A1 (ru) * | 1977-11-02 | 1980-04-15 | Институт биоорганической химии им.М.М.Шемякина | Гликопептиды,обладающие противоопухолевой активностью и способ их получени |
-
1979
- 1979-04-27 US US06/033,597 patent/US4391800A/en not_active Expired - Lifetime
-
1980
- 1980-04-25 EP EP80400566A patent/EP0018901B1/de not_active Expired
- 1980-04-25 DK DK177580A patent/DK177580A/da unknown
- 1980-04-25 DE DE8080400566T patent/DE3061322D1/de not_active Expired
- 1980-04-25 AT AT80400566T patent/ATE2006T1/de not_active IP Right Cessation
- 1980-04-28 JP JP5554480A patent/JPS55145696A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS55145696A (en) | 1980-11-13 |
| EP0018901B1 (de) | 1982-12-15 |
| EP0018901A1 (de) | 1980-11-12 |
| DK177580A (da) | 1980-10-28 |
| US4391800A (en) | 1983-07-05 |
| DE3061322D1 (en) | 1983-01-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |