ATE2006T1 - Peptidyl-disaccharide mit immunologischer aktivitaet, verfahren zur herstellung und impfstoff. - Google Patents

Peptidyl-disaccharide mit immunologischer aktivitaet, verfahren zur herstellung und impfstoff.

Info

Publication number
ATE2006T1
ATE2006T1 AT80400566T AT80400566T ATE2006T1 AT E2006 T1 ATE2006 T1 AT E2006T1 AT 80400566 T AT80400566 T AT 80400566T AT 80400566 T AT80400566 T AT 80400566T AT E2006 T1 ATE2006 T1 AT E2006T1
Authority
AT
Austria
Prior art keywords
substituted
alkyl
benzyl
phenyl
stereochemistry
Prior art date
Application number
AT80400566T
Other languages
English (en)
Inventor
Philippe L. Durette
Tsung-Ying Shen
Original Assignee
Merck & Co. Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. Inc. filed Critical Merck & Co. Inc.
Application granted granted Critical
Publication of ATE2006T1 publication Critical patent/ATE2006T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
AT80400566T 1979-04-27 1980-04-25 Peptidyl-disaccharide mit immunologischer aktivitaet, verfahren zur herstellung und impfstoff. ATE2006T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/033,597 US4391800A (en) 1979-04-27 1979-04-27 Immunologically active peptidyl disaccharides and methods of preparation
EP80400566A EP0018901B1 (de) 1979-04-27 1980-04-25 Peptidyl-Disaccharide mit immunologischer Aktivität, Verfahren zur Herstellung und Impfstoff

Publications (1)

Publication Number Publication Date
ATE2006T1 true ATE2006T1 (de) 1982-12-15

Family

ID=21871319

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80400566T ATE2006T1 (de) 1979-04-27 1980-04-25 Peptidyl-disaccharide mit immunologischer aktivitaet, verfahren zur herstellung und impfstoff.

Country Status (6)

Country Link
US (1) US4391800A (de)
EP (1) EP0018901B1 (de)
JP (1) JPS55145696A (de)
AT (1) ATE2006T1 (de)
DE (1) DE3061322D1 (de)
DK (1) DK177580A (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58198496A (ja) * 1982-05-14 1983-11-18 Dainippon Pharmaceut Co Ltd グルコサミニルムラミルペプチド誘導体
US4668661A (en) * 1984-10-23 1987-05-26 President & Fellows Of Harvard College Sleep inducing agents
GB8519416D0 (en) * 1985-08-01 1985-09-04 Unilever Plc Oligosaccharides
US4950645A (en) * 1988-07-08 1990-08-21 Immunotherapeutics, Inc. Composition for macrophage activation
US5416070A (en) * 1988-07-08 1995-05-16 Immunotherapeutics, Inc. Composition for macrophage activation
US5750665A (en) * 1995-10-04 1998-05-12 Vosika; Gerald J. Preparation of glucosaminyl muramic acid derivatives
AU2001252921A1 (en) * 2000-04-18 2001-10-30 Eli Lilly And Company A glycopeptide and preparation thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2326930A1 (fr) * 1975-10-09 1977-05-06 Anvar Agents hydrosolubles depresseurs non specifiques des reponses immunitaires
FR2343483A1 (fr) 1976-03-10 1977-10-07 Anvar L'ester methylique de la 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-alanyl-d-isoglutamine et le diester methylique de l'acide 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-alanyl-d-glutamique et medicaments les contenant
FR2343482A1 (fr) 1976-03-10 1977-10-07 Anvar La 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-seryl-d-isoglutamine et medicaments la contenant
US4082735A (en) * 1976-04-26 1978-04-04 Syntex (U.S.A.) Inc. Novel immunological adjuvant compounds and methods of preparation thereof
US4082736A (en) * 1976-04-26 1978-04-04 Syntex (U.S.A.) Inc. Novel immunological adjuvant compounds and methods of preparation thereof
GB1563561A (en) * 1976-06-23 1980-03-26 Daiichi Seiyaku Co Muramyldipeptide derivatives and process for the preparation thereof
FR2355505A1 (fr) 1976-06-24 1978-01-20 Anvar Nouvel agent adjuvant immunitaire
SU727647A1 (ru) * 1977-11-02 1980-04-15 Институт биоорганической химии им.М.М.Шемякина Гликопептиды,обладающие противоопухолевой активностью и способ их получени

Also Published As

Publication number Publication date
DE3061322D1 (en) 1983-01-20
US4391800A (en) 1983-07-05
EP0018901A1 (de) 1980-11-12
JPS55145696A (en) 1980-11-13
DK177580A (da) 1980-10-28
EP0018901B1 (de) 1982-12-15

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Legal Events

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