ATE199013T1 - N-(4-substituerte benzyl)-2-aminolactamderivate - Google Patents
N-(4-substituerte benzyl)-2-aminolactamderivateInfo
- Publication number
- ATE199013T1 ATE199013T1 AT96925667T AT96925667T ATE199013T1 AT E199013 T1 ATE199013 T1 AT E199013T1 AT 96925667 T AT96925667 T AT 96925667T AT 96925667 T AT96925667 T AT 96925667T AT E199013 T1 ATE199013 T1 AT E199013T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- substituted benzyl
- sec
- aminolactam
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9515411.8A GB9515411D0 (en) | 1995-07-27 | 1995-07-27 | N-(4-substituted-benzyl)-2-aminolactam derivatives |
| PCT/EP1996/002962 WO1997005111A1 (en) | 1995-07-27 | 1996-07-05 | N-(4-substituted-benzyl)-2-aminolactam derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE199013T1 true ATE199013T1 (de) | 2001-02-15 |
Family
ID=10778351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96925667T ATE199013T1 (de) | 1995-07-27 | 1996-07-05 | N-(4-substituerte benzyl)-2-aminolactamderivate |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5912242A (de) |
| EP (1) | EP0842152B1 (de) |
| JP (1) | JP3939755B2 (de) |
| AT (1) | ATE199013T1 (de) |
| AU (1) | AU6611696A (de) |
| BR (1) | BR9609847A (de) |
| CA (1) | CA2226886C (de) |
| DE (1) | DE69611728T2 (de) |
| ES (1) | ES2154830T3 (de) |
| GB (1) | GB9515411D0 (de) |
| IL (1) | IL122706A0 (de) |
| WO (1) | WO1997005111A1 (de) |
| ZA (1) | ZA965997B (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
| US6489319B2 (en) * | 1999-08-16 | 2002-12-03 | Revaax Pharmaceuticals, Llc | Neurotherapeutic use of carboxypeptidase inhibitors |
| EP1206261B1 (de) | 1999-08-16 | 2006-03-08 | Revaax Pharmaceuticals LLC | Pharmazeutische zubereitungen die clavulansäure oder derivate enthalten zur behandlund von neurologischen störungen |
| US6426342B2 (en) * | 1999-08-16 | 2002-07-30 | Revaax Pharmaceuticals, Llc | Use of β-lactamase inhibitors as neuroprotectants |
| AU2002333374B2 (en) | 2001-09-03 | 2007-03-22 | Newron Pharmaceuticals S.P.A. | Pharmaceutical composition comprising gabapentin or an analogue thereof and an (alpha)- aminoamide and its analgesic use |
| EP1438956A1 (de) | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-Aminoamidderivate die als Antimigränemittel nützlich sind |
| US7163937B2 (en) | 2003-08-21 | 2007-01-16 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| EP1524267A1 (de) * | 2003-10-15 | 2005-04-20 | Newron Pharmaceuticals S.p.A. | Substituierte Benzylaminoalkylen-Heterozyklen |
| EP1533298A1 (de) * | 2003-11-21 | 2005-05-25 | Newron Pharmaceuticals S.p.A. | 3-aminopyrrolidonederivate |
| EP1588704A1 (de) | 2004-04-22 | 2005-10-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamidderivate zur Behandlung des Restless-Leg-Syndroms und der Suchterkrankungen |
| EP1870097A1 (de) | 2006-06-15 | 2007-12-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamidederivate zur Behandlung von kognitiven Störungen |
| US7671062B2 (en) | 2006-07-28 | 2010-03-02 | Bristol-Myers Squibb Company | Modulators of chemokine receptor activity, crystalline forms and process |
| US7629351B2 (en) | 2006-07-28 | 2009-12-08 | Bristol-Myers Squibb Company | N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-2-oxo-3-(6-(trifluoromethyl)quinazolin-4-ylamino) pyrrolidin-1-yl)cyclohexyl)acetamide and other modulators of chemokine receptor activity, crystalline forms and process |
| US7687508B2 (en) | 2006-07-28 | 2010-03-30 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| JP2012525427A (ja) * | 2009-04-29 | 2012-10-22 | レクサン ファーマシューティカルズ インコーポレイテッド | 神経保護および神経変性疾患の治療のためのクラブラン酸塩製剤 |
| US8383812B2 (en) | 2009-10-13 | 2013-02-26 | Bristol-Myers Squibb Company | N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-A][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide, a dual modulator of chemokine receptor activity, crystalline forms and processes |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU518986B2 (en) * | 1977-10-11 | 1981-10-29 | Takeda Chemical Industries Ltd. | Lactams |
| US4719207A (en) * | 1984-06-25 | 1988-01-12 | Yamanouchi Pharmaceutical Co., Ltd. | CNS active substituted azetidinone compounds |
| GB8823605D0 (en) * | 1988-10-07 | 1988-11-16 | Merck Sharp & Dohme | Therapeutic agents |
-
1995
- 1995-07-27 GB GBGB9515411.8A patent/GB9515411D0/en active Pending
-
1996
- 1996-07-05 US US08/981,493 patent/US5912242A/en not_active Expired - Lifetime
- 1996-07-05 IL IL12270696A patent/IL122706A0/xx unknown
- 1996-07-05 EP EP96925667A patent/EP0842152B1/de not_active Expired - Lifetime
- 1996-07-05 AT AT96925667T patent/ATE199013T1/de not_active IP Right Cessation
- 1996-07-05 JP JP50714897A patent/JP3939755B2/ja not_active Expired - Lifetime
- 1996-07-05 ES ES96925667T patent/ES2154830T3/es not_active Expired - Lifetime
- 1996-07-05 CA CA002226886A patent/CA2226886C/en not_active Expired - Lifetime
- 1996-07-05 AU AU66116/96A patent/AU6611696A/en not_active Abandoned
- 1996-07-05 DE DE69611728T patent/DE69611728T2/de not_active Expired - Lifetime
- 1996-07-05 WO PCT/EP1996/002962 patent/WO1997005111A1/en active IP Right Grant
- 1996-07-05 BR BR9609847A patent/BR9609847A/pt not_active Application Discontinuation
- 1996-07-15 ZA ZA965997A patent/ZA965997B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997005111A1 (en) | 1997-02-13 |
| JP3939755B2 (ja) | 2007-07-04 |
| CA2226886C (en) | 2007-01-30 |
| CA2226886A1 (en) | 1997-02-13 |
| DE69611728T2 (de) | 2001-05-10 |
| BR9609847A (pt) | 1999-03-09 |
| EP0842152B1 (de) | 2001-01-31 |
| JPH11509848A (ja) | 1999-08-31 |
| IL122706A0 (en) | 1998-08-16 |
| DE69611728D1 (de) | 2001-03-08 |
| AU6611696A (en) | 1997-02-26 |
| ZA965997B (en) | 1997-01-31 |
| ES2154830T3 (es) | 2001-04-16 |
| EP0842152A1 (de) | 1998-05-20 |
| GB9515411D0 (en) | 1995-09-27 |
| US5912242A (en) | 1999-06-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE199013T1 (de) | N-(4-substituerte benzyl)-2-aminolactamderivate | |
| NO306346B1 (no) | N-substituerte azabicykloalkanderivater, anvendelse derav og farmasöytisk preparat | |
| NO963850D0 (no) | Heterosykliske forbindelser, deres fremstilling og anvendelse | |
| BR9611175B1 (pt) | compostos e composiÇÕes farmacÊuticas. | |
| NO963053L (no) | Kosmetiske eller farmasöytiske preparater inneholdende mangiferin eller derivater derav | |
| PT958296E (pt) | Compostos heterociclicos processo para a sua preparacao composicoes farmaceuticas contendo-os e sua utilizacao no tratamento da diabetes e doencas relacionadas | |
| FR2743562B1 (fr) | Derives de n-(arylsulfonyl) aminoacides, leur preparation, les compositions pharmaceutiques en contenant | |
| MXPA02001340A (es) | Compuestos novedosos 1,4-benzodiazepina y derivados de los mismos. | |
| FI972434A (fi) | Lamotrigiiniä sisältävä farmaseuttinen koostumus | |
| DK0810991T3 (da) | 1-Aryl-2-acylamino-ethan-forbindelser og deres anvendelse som neurokinin- især neurokinin-1-antagonister | |
| ATE233246T1 (de) | Hydantoinderivate als zwischenprodukte für pharmazeutische wirkstoffe | |
| DK0891341T3 (da) | 1,3,4-Oxadiazinderivater samt deres anvendelse som pesticider | |
| NO306400B1 (no) | N-substituerte azabicykloheptan-derivater, anvendelse derav og farmasöytisk preparat | |
| DK0775143T3 (da) | 3-substituerede 3H-2,3-benzodiazepinderivater, deres fremstilling og anvendelse som lægdemidler | |
| BR9610175A (pt) | Composto processo de preparação do composto composição farmacêutica e utilização do composto | |
| PL323305A1 (en) | Applications of allyl amines | |
| DK0805817T3 (da) | Thiolderivater med metallopeptidaseinhiberende aktivitet | |
| DK0815109T3 (da) | Fremgangsmåde til fremstilling af estere af anhydroecgonin | |
| ZA955052B (en) | Pyrrolidine derivatives their preparation and compositions containing them | |
| CA2241788A1 (fr) | Nouveaux derives de n-(arylsulfonyl)aminoacides, leur procede de preparation et compositions pharmaceutiques en contenant |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |