ATE194493T1 - Verfahren zur behandlung von hyperproliferaktiven gefässerkrankungen unter verwendung von rapamycin, eventuell in kombination mit mykophenolsäure - Google Patents
Verfahren zur behandlung von hyperproliferaktiven gefässerkrankungen unter verwendung von rapamycin, eventuell in kombination mit mykophenolsäureInfo
- Publication number
- ATE194493T1 ATE194493T1 AT93300052T AT93300052T ATE194493T1 AT E194493 T1 ATE194493 T1 AT E194493T1 AT 93300052 T AT93300052 T AT 93300052T AT 93300052 T AT93300052 T AT 93300052T AT E194493 T1 ATE194493 T1 AT E194493T1
- Authority
- AT
- Austria
- Prior art keywords
- treating
- combination
- rapamycin
- mycophenolic acid
- hyperproliferactive
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81931492A | 1992-01-09 | 1992-01-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE194493T1 true ATE194493T1 (de) | 2000-07-15 |
Family
ID=25227805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT93300052T ATE194493T1 (de) | 1992-01-09 | 1993-01-06 | Verfahren zur behandlung von hyperproliferaktiven gefässerkrankungen unter verwendung von rapamycin, eventuell in kombination mit mykophenolsäure |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0551182B1 (de) |
JP (1) | JP2644955B2 (de) |
KR (1) | KR100276142B1 (de) |
AT (1) | ATE194493T1 (de) |
AU (1) | AU665041B2 (de) |
CA (1) | CA2086642C (de) |
DE (1) | DE69328981T2 (de) |
DK (1) | DK0551182T3 (de) |
ES (1) | ES2147740T3 (de) |
GR (1) | GR3034479T3 (de) |
HK (1) | HK1010332A1 (de) |
LV (1) | LV12603B (de) |
NZ (1) | NZ245630A (de) |
PT (1) | PT551182E (de) |
SG (1) | SG47639A1 (de) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6515009B1 (en) * | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5516781A (en) * | 1992-01-09 | 1996-05-14 | American Home Products Corporation | Method of treating restenosis with rapamycin |
US5283257A (en) * | 1992-07-10 | 1994-02-01 | The Board Of Trustees Of The Leland Stanford Junior University | Method of treating hyperproliferative vascular disease |
US6663881B2 (en) | 1993-01-28 | 2003-12-16 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5981568A (en) | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
DK1155689T3 (da) | 1993-07-19 | 2006-11-20 | Angiotech Pharm Inc | Antiangiogene stents og fremgangsmåder til fremstilling heraf |
US5527907A (en) * | 1993-11-19 | 1996-06-18 | Abbott Laboratories | Macrolide immunomodulators |
CA2175215C (en) * | 1993-11-19 | 2008-06-03 | Yat Sun Or | Semisynthetic analogs of rapamycin (macrolides) being immunomodulators |
US5519042A (en) * | 1994-01-13 | 1996-05-21 | Hoechst Aktiengesellschaft | Method of treating hyperproliferative vascular disease |
US5444072A (en) * | 1994-02-18 | 1995-08-22 | Syntex (U.S.A.) Inc. | 6-substituted mycophenolic acid and derivatives |
US6558798B2 (en) | 1995-02-22 | 2003-05-06 | Scimed Life Systems, Inc. | Hydrophilic coating and substrates coated therewith having enhanced durability and lubricity |
US5605696A (en) * | 1995-03-30 | 1997-02-25 | Advanced Cardiovascular Systems, Inc. | Drug loaded polymeric material and method of manufacture |
NZ311647A (en) | 1995-06-09 | 1999-11-29 | Novartis Ag | Rapamycin derivatives |
KR100616020B1 (ko) * | 1996-03-27 | 2007-01-31 | 노파르티스 아게 | 맥관장애및이종이식술에서의라파마이신유도체의용도 |
GB9606452D0 (en) * | 1996-03-27 | 1996-06-05 | Sandoz Ltd | Organic compounds |
ID18663A (id) | 1996-04-12 | 1998-04-30 | Novartis Ag | Komposisi farmasi berlapis enterik |
US6495579B1 (en) | 1996-12-02 | 2002-12-17 | Angiotech Pharmaceuticals, Inc. | Method for treating multiple sclerosis |
US6515016B2 (en) | 1996-12-02 | 2003-02-04 | Angiotech Pharmaceuticals, Inc. | Composition and methods of paclitaxel for treating psoriasis |
IT1289815B1 (it) | 1996-12-30 | 1998-10-16 | Sorin Biomedica Cardio Spa | Stent per angioplastica e relativo procedimento di produzione |
US6273913B1 (en) † | 1997-04-18 | 2001-08-14 | Cordis Corporation | Modified stent useful for delivery of drugs along stent strut |
US7208010B2 (en) | 2000-10-16 | 2007-04-24 | Conor Medsystems, Inc. | Expandable medical device for delivery of beneficial agent |
US6241762B1 (en) | 1998-03-30 | 2001-06-05 | Conor Medsystems, Inc. | Expandable medical device with ductile hinges |
US6120847A (en) * | 1999-01-08 | 2000-09-19 | Scimed Life Systems, Inc. | Surface treatment method for stent coating |
US6419692B1 (en) | 1999-02-03 | 2002-07-16 | Scimed Life Systems, Inc. | Surface protection method for stents and balloon catheters for drug delivery |
US6156373A (en) * | 1999-05-03 | 2000-12-05 | Scimed Life Systems, Inc. | Medical device coating methods and devices |
US6258121B1 (en) | 1999-07-02 | 2001-07-10 | Scimed Life Systems, Inc. | Stent coating |
US6251136B1 (en) | 1999-12-08 | 2001-06-26 | Advanced Cardiovascular Systems, Inc. | Method of layering a three-coated stent using pharmacological and polymeric agents |
US6702849B1 (en) | 1999-12-13 | 2004-03-09 | Advanced Cardiovascular Systems, Inc. | Method of processing open-celled microcellular polymeric foams with controlled porosity for use as vascular grafts and stent covers |
AU2001294634B2 (en) | 2000-10-16 | 2006-07-06 | Innovational Holdings, Llc | Expandable medical device for delivery of beneficial agent |
DE10115740A1 (de) | 2001-03-26 | 2002-10-02 | Ulrich Speck | Zubereitung für die Restenoseprophylaxe |
US7842083B2 (en) | 2001-08-20 | 2010-11-30 | Innovational Holdings, Llc. | Expandable medical device with improved spatial distribution |
US7682387B2 (en) | 2002-04-24 | 2010-03-23 | Biosensors International Group, Ltd. | Drug-delivery endovascular stent and method for treating restenosis |
US6939376B2 (en) | 2001-11-05 | 2005-09-06 | Sun Biomedical, Ltd. | Drug-delivery endovascular stent and method for treating restenosis |
US7097850B2 (en) | 2002-06-18 | 2006-08-29 | Surmodics, Inc. | Bioactive agent release coating and controlled humidity method |
DE10244847A1 (de) | 2002-09-20 | 2004-04-01 | Ulrich Prof. Dr. Speck | Medizinische Vorrichtung zur Arzneimittelabgabe |
ATE538820T1 (de) | 2003-02-21 | 2012-01-15 | Sorin Biomedica Cardio Srl | Verfahren zur herstellung eines stents und entsprechender stent |
AR045957A1 (es) * | 2003-10-03 | 2005-11-16 | Novartis Ag | Composicion farmaceutica y combinacion |
US7303758B2 (en) * | 2004-01-20 | 2007-12-04 | Cordis Corporation | Local vascular delivery of mycophenolic acid in combination with rapamycin to prevent restenosis following vascular injury |
JP5141254B2 (ja) | 2005-10-06 | 2013-02-13 | 株式会社カネカ | 生体留置用ステント |
JP2010500889A (ja) | 2006-07-03 | 2010-01-14 | ヘモテック アーゲー | 恒久的に血管を開いた状態にするための薬剤溶出医療デバイスの製造、方法、および使用 |
BRPI0806727B8 (pt) | 2007-01-21 | 2021-06-22 | Hemoteq Ag | método para o revestimento de um cateter de balão |
US9192697B2 (en) | 2007-07-03 | 2015-11-24 | Hemoteq Ag | Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis |
WO2009089549A1 (en) | 2008-01-11 | 2009-07-16 | Massachusetts Eye & Ear Infirmary | Conditional-stop dimerizable caspase transgenic animals |
WO2011005421A2 (en) | 2009-07-10 | 2011-01-13 | Boston Scientific Scimed, Inc. | Use of nanocrystals for a drug delivery balloon |
US10080821B2 (en) | 2009-07-17 | 2018-09-25 | Boston Scientific Scimed, Inc. | Nucleation of drug delivery balloons to provide improved crystal size and density |
WO2012031236A1 (en) | 2010-09-02 | 2012-03-08 | Boston Scientific Scimed, Inc. | Coating process for drug delivery balloons using heat-induced rewrap memory |
WO2013022458A1 (en) | 2011-08-05 | 2013-02-14 | Boston Scientific Scimed, Inc. | Methods of converting amorphous drug substance into crystalline form |
WO2013028208A1 (en) | 2011-08-25 | 2013-02-28 | Boston Scientific Scimed, Inc. | Medical device with crystalline drug coating |
JP6278332B2 (ja) | 2013-04-22 | 2018-02-14 | スズキ株式会社 | 変速機の制御装置 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5078999A (en) * | 1991-02-22 | 1992-01-07 | American Home Products Corporation | Method of treating systemic lupus erythematosus |
-
1993
- 1993-01-04 CA CA002086642A patent/CA2086642C/en not_active Expired - Lifetime
- 1993-01-06 ES ES93300052T patent/ES2147740T3/es not_active Expired - Lifetime
- 1993-01-06 DE DE69328981T patent/DE69328981T2/de not_active Expired - Lifetime
- 1993-01-06 PT PT93300052T patent/PT551182E/pt unknown
- 1993-01-06 SG SG1996003304A patent/SG47639A1/en unknown
- 1993-01-06 EP EP93300052A patent/EP0551182B1/de not_active Expired - Lifetime
- 1993-01-06 AT AT93300052T patent/ATE194493T1/de active
- 1993-01-06 DK DK93300052T patent/DK0551182T3/da active
- 1993-01-07 NZ NZ245630A patent/NZ245630A/en not_active IP Right Cessation
- 1993-01-07 AU AU31079/93A patent/AU665041B2/en not_active Expired
- 1993-01-08 KR KR1019930000174A patent/KR100276142B1/ko not_active IP Right Cessation
- 1993-01-08 JP JP5001773A patent/JP2644955B2/ja not_active Expired - Lifetime
-
1998
- 1998-09-25 HK HK98110984A patent/HK1010332A1/xx not_active IP Right Cessation
-
2000
- 2000-09-26 GR GR20000402168T patent/GR3034479T3/el unknown
- 2000-10-06 LV LVP-00-134A patent/LV12603B/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP0551182A1 (de) | 1993-07-14 |
NZ245630A (en) | 1997-07-27 |
ES2147740T3 (es) | 2000-10-01 |
SG47639A1 (en) | 1998-04-17 |
KR100276142B1 (ko) | 2001-02-01 |
JPH069390A (ja) | 1994-01-18 |
AU3107993A (en) | 1993-07-15 |
PT551182E (pt) | 2000-12-29 |
KR930016102A (ko) | 1993-08-26 |
AU665041B2 (en) | 1995-12-14 |
LV12603B (en) | 2001-04-20 |
EP0551182B1 (de) | 2000-07-12 |
JP2644955B2 (ja) | 1997-08-25 |
DE69328981D1 (de) | 2000-08-17 |
HK1010332A1 (en) | 1999-06-17 |
CA2086642C (en) | 2004-06-15 |
CA2086642A1 (en) | 1993-07-10 |
DK0551182T3 (da) | 2000-10-09 |
GR3034479T3 (en) | 2000-12-29 |
LV12603A (en) | 2001-01-20 |
DE69328981T2 (de) | 2000-11-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |