ATE191224T1 - Tnf-inhibitoren - Google Patents

Tnf-inhibitoren

Info

Publication number
ATE191224T1
ATE191224T1 AT94116015T AT94116015T ATE191224T1 AT E191224 T1 ATE191224 T1 AT E191224T1 AT 94116015 T AT94116015 T AT 94116015T AT 94116015 T AT94116015 T AT 94116015T AT E191224 T1 ATE191224 T1 AT E191224T1
Authority
AT
Austria
Prior art keywords
tnf
tnf inhibitors
ligands
receptors
inhibit
Prior art date
Application number
AT94116015T
Other languages
English (en)
Inventor
David Wallach
Jacek Bigda
Igor Beletsky
Igor Mett
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Application granted granted Critical
Publication of ATE191224T1 publication Critical patent/ATE191224T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
AT94116015T 1993-10-12 1994-10-11 Tnf-inhibitoren ATE191224T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL107267A IL107267A (en) 1993-10-12 1993-10-12 Ligand to a member of the tnf/ngf receptor family

Publications (1)

Publication Number Publication Date
ATE191224T1 true ATE191224T1 (de) 2000-04-15

Family

ID=11065339

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94116015T ATE191224T1 (de) 1993-10-12 1994-10-11 Tnf-inhibitoren

Country Status (12)

Country Link
EP (1) EP0648783B1 (de)
JP (1) JPH07188298A (de)
AT (1) ATE191224T1 (de)
AU (1) AU683298B2 (de)
CA (1) CA2133873C (de)
DE (1) DE69423697T2 (de)
DK (1) DK0648783T3 (de)
ES (1) ES2146243T3 (de)
GR (1) GR3033468T3 (de)
IL (1) IL107267A (de)
PT (1) PT648783E (de)
ZA (1) ZA947961B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6232446B1 (en) * 1989-05-18 2001-05-15 Yeda Research And Development Co. Ltd. TNF ligands
US6262239B1 (en) * 1989-05-18 2001-07-17 Yeda Research And Development Co., Ltd. TNF receptor-specific antibodies
IL139574A0 (en) * 1998-05-18 2002-02-10 Applied Research Systems TNF-RII (p75) AGONISTS FOR TREATING ASTHMA AND OTHER ALLERGIC CONDITIONS
US6627199B1 (en) 1999-07-09 2003-09-30 Amgen Inc Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family
WO2001010908A1 (en) 1999-08-04 2001-02-15 Amgen Inc. Ntr3, a member of the tnf-receptor supergene family
EP1210435A1 (de) 1999-08-04 2002-06-05 Amgen Inc. Fhm, EIN NEUES MITGLIED DER TUMOR NECROSIS FAKTOR (TNF) SUPERGEN FAMILIE
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
PT2087908T (pt) 2001-06-26 2018-07-16 Amgen Inc Anticorpos contra opgl
WO2003009864A1 (en) * 2001-07-23 2003-02-06 Genset S.A. Agonists and antagonists of disomet for the treatment of metabolic disorders
US9028822B2 (en) 2002-06-28 2015-05-12 Domantis Limited Antagonists against TNFR1 and methods of use therefor
JP2006517191A (ja) 2002-12-30 2006-07-20 アムジエン・インコーポレーテツド 共刺激因子を用いた併用療法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL94039A (en) * 1989-08-06 2006-09-05 Yeda Res & Dev Antibodies to tbp - 1 and their use
IL106271A (en) * 1992-09-03 2008-03-20 Yeda Res & Dev Ligand to TNF 75P receptor and its preparation
AU636608B2 (en) * 1989-05-18 1993-05-06 Yeda Research And Development Co. Ltd. Tumor necrosis factor binding protein II, it's purification and antibodies thereto

Also Published As

Publication number Publication date
EP0648783A1 (de) 1995-04-19
AU7574394A (en) 1995-05-04
EP0648783B1 (de) 2000-03-29
PT648783E (pt) 2000-08-31
ES2146243T3 (es) 2000-08-01
AU683298B2 (en) 1997-11-06
CA2133873A1 (en) 1995-04-13
GR3033468T3 (en) 2000-09-29
DK0648783T3 (da) 2000-08-14
IL107267A (en) 2009-07-20
IL107267A0 (en) 1994-01-25
DE69423697T2 (de) 2000-11-09
JPH07188298A (ja) 1995-07-25
DE69423697D1 (de) 2000-05-04
ZA947961B (en) 1995-05-24
CA2133873C (en) 2010-08-03

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification