ATE190505T1 - Verwendung von ibuprofen-beta-cyclodextrin- komplex für die orale verabreichung - Google Patents
Verwendung von ibuprofen-beta-cyclodextrin- komplex für die orale verabreichungInfo
- Publication number
- ATE190505T1 ATE190505T1 AT93907987T AT93907987T ATE190505T1 AT E190505 T1 ATE190505 T1 AT E190505T1 AT 93907987 T AT93907987 T AT 93907987T AT 93907987 T AT93907987 T AT 93907987T AT E190505 T1 ATE190505 T1 AT E190505T1
- Authority
- AT
- Austria
- Prior art keywords
- ibuprofen
- beta
- pct
- cyclodextrin complex
- oral administration
- Prior art date
Links
- 229920000858 Cyclodextrin Polymers 0.000 title abstract 2
- 239000001116 FEMA 4028 Substances 0.000 title abstract 2
- 229960004853 betadex Drugs 0.000 title abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 235000011175 beta-cyclodextrine Nutrition 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nanotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929207990A GB9207990D0 (en) | 1992-04-10 | 1992-04-10 | Pharmaceutical composition |
| PCT/GB1993/000702 WO1993020850A1 (en) | 1992-04-10 | 1993-04-02 | Pharmaceutical composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE190505T1 true ATE190505T1 (de) | 2000-04-15 |
Family
ID=10713877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93907987T ATE190505T1 (de) | 1992-04-10 | 1993-04-02 | Verwendung von ibuprofen-beta-cyclodextrin- komplex für die orale verabreichung |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5597583A (de) |
| EP (1) | EP0633787B1 (de) |
| JP (1) | JPH07505645A (de) |
| KR (1) | KR950700762A (de) |
| AT (1) | ATE190505T1 (de) |
| AU (1) | AU667095B2 (de) |
| CA (1) | CA2117762A1 (de) |
| DE (1) | DE69328087T2 (de) |
| ES (1) | ES2145772T3 (de) |
| GB (1) | GB9207990D0 (de) |
| NZ (1) | NZ251393A (de) |
| WO (1) | WO1993020850A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9507768A (pt) * | 1994-05-27 | 1997-09-02 | Farmarc Nederland Bv | Composição farmacêutica |
| GB9625589D0 (en) * | 1996-12-10 | 1997-01-29 | Boots Co Plc | Therapeutic agents |
| IT1301966B1 (it) | 1998-07-30 | 2000-07-20 | Zambon Spa | Composizioni farmaceutiche ad attivita' analgesica |
| US6211246B1 (en) * | 1999-06-10 | 2001-04-03 | Mcneil-Ppc, Inc. | Rapidly absorbed liquid compositions |
| ES2171110B1 (es) * | 2000-03-03 | 2003-06-16 | Aplicaciones Farmacodinamicas | Composicion farmaceutica a base de ibuprofeno y procedimiento para su preparacion. |
| NZ524348A (en) * | 2000-08-02 | 2004-07-30 | Malope Company Ltd | Diagnosis and treatment of non-ulcer dyspepsia based on dysfunction in the corticotropin releasing hormone (CRH) receptor and repsonse to ACTH |
| AU2002327418A1 (en) * | 2001-08-01 | 2003-02-17 | Bristol-Myers Squibb Company | Taste masking composition |
| KR100567131B1 (ko) * | 2004-01-05 | 2006-04-05 | 신일제약주식회사 | 쓴맛을 차폐한 아르기닌 함유 이부프로펜 경구투여 액상조성물 |
| AU2006312119B2 (en) * | 2005-11-02 | 2010-04-29 | Teikoku Pharma Usa, Inc. | Organoleptically acceptable ibuprofen oral dosage formulations, methods of making and using the same |
| US20070207206A1 (en) * | 2006-03-02 | 2007-09-06 | Rice Bronwyn C | Chewable pain formula |
| RU2437657C2 (ru) * | 2006-03-16 | 2011-12-27 | Новартис Аг | Твердая лекарственная форма, содержащая активный агент с маскированным вкусом |
| EP2253329B1 (de) * | 2009-04-27 | 2016-09-21 | Laboratorio de Aplicaciones Farmacodinamicas, S.A. | Orale Ibuprofenlysinat-Suspension |
| JP5977672B2 (ja) * | 2009-04-27 | 2016-08-24 | ラボラトリオ デ アプリカシオネス ファルマコディナミカス,エセ.アー.Laboratorio De Aplicaciones Farmacodinamicas,S.A. | イブプロフェンリシナートの経口投与用の懸濁液 |
| CN114588107B (zh) * | 2022-04-06 | 2023-04-18 | 河北一品生物医药有限公司 | 一种布洛芬赖氨酸盐注射液及其制备方法 |
| EP4516290A1 (de) | 2023-08-31 | 2025-03-05 | Grindeks, A Joint Stock Company | Pharmazeutische zusammensetzung aus einer kombination aus einem nichtsteroidalen antirheumatikum und einem dekongestivum in pulverform oder granulat zur herstellung eines heissgetränks |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| YU43290B (en) * | 1986-11-13 | 1989-06-30 | Lek Tovarna Farmacevtskih | Process for preparing inclusioned complex of ibuproxane with beta-cyclodextrine |
| CA1298290C (en) * | 1987-01-09 | 1992-03-31 | Herand M. Markarian | Solution ibuprofen complexes, compositions and processes for preparing the same |
| GB8813682D0 (en) * | 1988-06-09 | 1988-07-13 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions |
| US5024997A (en) * | 1990-06-22 | 1991-06-18 | American Home Products Corporation | Palatable ibuprofen solutions |
| DE4038314A1 (de) * | 1990-11-30 | 1992-06-04 | Puetter Medice Chem Pharm | Komplexe des aktiven enantiomers des ibuprofens mit cyclodextrin |
-
1992
- 1992-04-10 GB GB929207990A patent/GB9207990D0/en active Pending
-
1993
- 1993-04-02 CA CA002117762A patent/CA2117762A1/en not_active Abandoned
- 1993-04-02 EP EP93907987A patent/EP0633787B1/de not_active Expired - Lifetime
- 1993-04-02 US US08/318,739 patent/US5597583A/en not_active Expired - Fee Related
- 1993-04-02 WO PCT/GB1993/000702 patent/WO1993020850A1/en not_active Ceased
- 1993-04-02 AT AT93907987T patent/ATE190505T1/de not_active IP Right Cessation
- 1993-04-02 DE DE69328087T patent/DE69328087T2/de not_active Expired - Lifetime
- 1993-04-02 JP JP5518085A patent/JPH07505645A/ja active Pending
- 1993-04-02 NZ NZ251393A patent/NZ251393A/en unknown
- 1993-04-02 ES ES93907987T patent/ES2145772T3/es not_active Expired - Lifetime
- 1993-04-02 AU AU38987/93A patent/AU667095B2/en not_active Ceased
-
1994
- 1994-10-10 KR KR1019940703598A patent/KR950700762A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0633787B1 (de) | 2000-03-15 |
| WO1993020850A1 (en) | 1993-10-28 |
| DE69328087T2 (de) | 2000-08-24 |
| US5597583A (en) | 1997-01-28 |
| JPH07505645A (ja) | 1995-06-22 |
| GB9207990D0 (en) | 1992-05-27 |
| ES2145772T3 (es) | 2000-07-16 |
| CA2117762A1 (en) | 1993-10-28 |
| HK1012260A1 (en) | 1999-07-30 |
| DE69328087D1 (de) | 2000-04-20 |
| KR950700762A (ko) | 1995-02-20 |
| AU3898793A (en) | 1993-11-18 |
| EP0633787A1 (de) | 1995-01-18 |
| NZ251393A (en) | 1996-08-27 |
| AU667095B2 (en) | 1996-03-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69328087D1 (de) | Verwendung von ibuprofen-beta-cyclodextrin-komplex für die orale verabreichung | |
| ATE163418T1 (de) | Risperidon pamoate | |
| TR199700844T1 (xx) | Pirazolil-Benzoil T�revleri. | |
| ATE131051T1 (de) | Indolderivate, die die leukotrienbiosynthese hemmen. | |
| AR038429A2 (es) | Compuestos 15-alquil-16-hidroxilo de marcfortina | |
| DK0696281T3 (da) | Hidtil ukendte 5-pyrrolyl-2-pyridylmethylsulfinylbenzimidazolderivater | |
| IL118167A0 (en) | Pyrazolo (1,5a) pyrimidines their preparation and use | |
| ATE205868T1 (de) | Monofilmmembran, verfahren zu ihrer herstellung und ihre verwendung | |
| DE69225410D1 (de) | Herstellung von n-acetylneuraminsäure-derivaten | |
| DK455088D0 (da) | Syntetiske receptoranaloger | |
| DE69224295D1 (de) | Pestizid und fungizid | |
| MX9401406A (es) | Agentes receptores de adenosina selectivos para intensificar el conocimiento. | |
| DE69622889D1 (de) | Substituierte 4-(1h-benzimidazol-2-yl)(1,4)diazepane für die behandlung von allergischen krankheiten | |
| NO941084D0 (no) | Neuroleptiske 2-substituerte perhydro-1-H-pyrido[1,2-aÅpyraziner | |
| ES8603506A1 (es) | Un procedimiento para la preparacion de 9-deoxo-9a-metil-9a-aza-9a-homoeritromicina b o una sal de la misma | |
| TR26431A (tr) | ANIYONIK AZO BOYAR MADDELERININ KONSANTRE, SULU CÖZELTILERININ üRETILMESINE MAHSUS USUL. | |
| FR2734724B1 (fr) | Application de derives de pyrrolidine a la preparation de medicaments destines au traitement de l'alcoolisme | |
| FI934977A0 (fi) | Foerfarande foer att reducera elkfoerbrukningen i mikroprocessorbaserade,isynnerhet foer publika telefonstationer avsedda anordningar | |
| DE69512087D1 (de) | Monoazopigmente | |
| ZA922102B (en) | Method of treatment | |
| ATE175971T1 (de) | Wasserlösliche retinoide | |
| PT871632E (pt) | Producao de um sal cristalino de amoxicilina | |
| ATE374188T1 (de) | Pestizide indazol-derivate | |
| HU9501691D0 (en) | New triazoloquinazolines, their production and their use | |
| ATE221068T1 (de) | Anellierte beta-carboline |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |