ATE176243T1 - Pacap-derivate mit c-amp-produzierenden eigenschaften - Google Patents

Pacap-derivate mit c-amp-produzierenden eigenschaften

Info

Publication number
ATE176243T1
ATE176243T1 AT92114102T AT92114102T ATE176243T1 AT E176243 T1 ATE176243 T1 AT E176243T1 AT 92114102 T AT92114102 T AT 92114102T AT 92114102 T AT92114102 T AT 92114102T AT E176243 T1 ATE176243 T1 AT E176243T1
Authority
AT
Austria
Prior art keywords
group
lys
substituted
leu
val
Prior art date
Application number
AT92114102T
Other languages
English (en)
Inventor
Chieko Kitada
Takuya Watanabe
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE176243T1 publication Critical patent/ATE176243T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AT92114102T 1991-08-22 1992-08-19 Pacap-derivate mit c-amp-produzierenden eigenschaften ATE176243T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21116191 1991-08-22

Publications (1)

Publication Number Publication Date
ATE176243T1 true ATE176243T1 (de) 1999-02-15

Family

ID=16601412

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92114102T ATE176243T1 (de) 1991-08-22 1992-08-19 Pacap-derivate mit c-amp-produzierenden eigenschaften

Country Status (5)

Country Link
US (2) US5623050A (de)
EP (1) EP0529487B1 (de)
AT (1) ATE176243T1 (de)
CA (1) CA2076593C (de)
DE (1) DE69228277T2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996034958A1 (en) * 1995-05-03 1996-11-07 Biostar Inc. Vasoactive intestinal peptide
US6037321A (en) * 1995-05-03 2000-03-14 Biostar Inc. Fusion proteins comprising vasoactive intestinal peptide or PACAP
US6017533A (en) * 1996-04-25 2000-01-25 Shiseido Company, Ltd. Peptides having specific affinity to pituitary adenylate cyclase activating polypeptide type 1 receptors
US6242563B1 (en) 1998-07-20 2001-06-05 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Peptide analogues
CZ2001253A3 (cs) * 1998-07-20 2001-11-14 Societe De Conseils De Recherches Et D'application Peptidové analogy PACAP
AU2002325712C1 (en) 2001-08-30 2008-07-31 Stem Cell Therapeutics Inc. Differentiation of neural stem cells and therapeutic use theeof
JP4906231B2 (ja) * 2001-09-14 2012-03-28 ステム セル セラピューティクス インコーポレイテッド プロラクチン誘導性の神経幹細胞数の増加ならびにその治療用途
US20030054551A1 (en) * 2001-09-18 2003-03-20 Stem Cell Therapeutics Inc. Effect of growth hormone and IGF-1 on neural stem cells
EP1549740A2 (de) * 2002-07-30 2005-07-06 Stem Cell Therapeutics Inc. Oligodendrozytenherstellung aus multipotenten nervenstammzellen
CA2492442A1 (en) * 2002-07-31 2004-02-05 Stem Cell Therapeutics Inc. Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (pacap)
WO2004048401A1 (ja) * 2002-11-27 2004-06-10 Itoham Foods Inc. ペプチド及びこれを含む医薬組成物
AU2005211847B2 (en) * 2004-02-13 2011-02-24 Stem Cell Therapeutics Corp. Use of luteinizing hormone (LH) and chorionic gonadotropin (hCG) for proliferation of neural stem cells and neurogenesis
EP2319531A3 (de) 2004-10-07 2011-09-07 Stem Cell Therapeutics Corp. Stimulation der Proliferation von pluripotenten Stammzellen durch Verabreichung von Schwangerschafts-assoziierten Verbindungen
US7007328B1 (en) * 2004-11-05 2006-03-07 Terry Bailey System and apparatus for upper body support of a recumbent person
JP2009509943A (ja) 2005-09-27 2009-03-12 ステム セル セラピューティクス コーポレイション プロラクチンにより制御される乏突起膠細胞前駆体細胞の増殖
WO2007106987A1 (en) * 2006-03-17 2007-09-27 Stem Cell Therapeutics Corp. Continuous dosing regimens for neural stem cell proliferating agents and neural stem cell differentiating agents
RU2615450C2 (ru) 2009-12-29 2017-04-04 Курна, Инк. Лечение заболеваний, связанных с ядерным респираторным фактором 1(nrf1), путем ингибирования природного антисмыслового транскрипта к nrf1
JPWO2019098254A1 (ja) * 2017-11-14 2020-12-03 千寿製薬株式会社 Ｐａｃａｐの安定化ペプチド

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562175A (en) * 1984-02-03 1985-12-31 Ding Chang Synthetic peptides
US4605641A (en) * 1984-10-09 1986-08-12 Hoffmann-La Roche Inc. Synthetic vasoactive intestinal peptide analogs
JPS62246595A (ja) * 1986-04-17 1987-10-27 Eisai Co Ltd 気菅支拡張作用・降圧作用ペプタイド
US5128242A (en) * 1989-06-19 1992-07-07 The Administrators Of The Tulane Educational Fund Hypothalamic polypeptides with adenylate cyclase stimulating activity
US5198542A (en) * 1989-06-20 1993-03-30 Takeda Chemical Industries, Inc. Dna encoding a pitvitary adenylate cyclase activating protein and use thereof
EP0467279A3 (en) * 1990-07-18 1992-08-05 Takeda Chemical Industries, Ltd. Polypeptides having c-amp producing activity

Also Published As

Publication number Publication date
EP0529487B1 (de) 1999-01-27
EP0529487A3 (en) 1994-06-22
CA2076593A1 (en) 1993-02-23
EP0529487A2 (de) 1993-03-03
US5623050A (en) 1997-04-22
US5801147A (en) 1998-09-01
DE69228277T2 (de) 1999-07-08
CA2076593C (en) 2002-06-04
DE69228277D1 (de) 1999-03-11

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties