ATE176243T1 - Pacap-derivate mit c-amp-produzierenden eigenschaften - Google Patents

Pacap-derivate mit c-amp-produzierenden eigenschaften

Info

Publication number
ATE176243T1
ATE176243T1 AT92114102T AT92114102T ATE176243T1 AT E176243 T1 ATE176243 T1 AT E176243T1 AT 92114102 T AT92114102 T AT 92114102T AT 92114102 T AT92114102 T AT 92114102T AT E176243 T1 ATE176243 T1 AT E176243T1
Authority
AT
Austria
Prior art keywords
group
lys
substituted
leu
val
Prior art date
Application number
AT92114102T
Other languages
English (en)
Inventor
Chieko Kitada
Takuya Watanabe
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE176243T1 publication Critical patent/ATE176243T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT92114102T 1991-08-22 1992-08-19 Pacap-derivate mit c-amp-produzierenden eigenschaften ATE176243T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21116191 1991-08-22

Publications (1)

Publication Number Publication Date
ATE176243T1 true ATE176243T1 (de) 1999-02-15

Family

ID=16601412

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92114102T ATE176243T1 (de) 1991-08-22 1992-08-19 Pacap-derivate mit c-amp-produzierenden eigenschaften

Country Status (5)

Country Link
US (2) US5623050A (de)
EP (1) EP0529487B1 (de)
AT (1) ATE176243T1 (de)
CA (1) CA2076593C (de)
DE (1) DE69228277T2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996034958A1 (en) * 1995-05-03 1996-11-07 Biostar Inc. Vasoactive intestinal peptide
US6037321A (en) * 1995-05-03 2000-03-14 Biostar Inc. Fusion proteins comprising vasoactive intestinal peptide or PACAP
US6017533A (en) * 1996-04-25 2000-01-25 Shiseido Company, Ltd. Peptides having specific affinity to pituitary adenylate cyclase activating polypeptide type 1 receptors
US6242563B1 (en) 1998-07-20 2001-06-05 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Peptide analogues
PL345583A1 (en) * 1998-07-20 2001-12-17 Sod Conseils Rech Applic Peptide analogues of pacap
US7048934B2 (en) * 2001-08-30 2006-05-23 Stem Cell Therapeutics Inc. Combined regulation of neural cell production
ATE541921T1 (de) * 2001-09-14 2012-02-15 Stem Cell Therapeutics Inc Prolaktin-induzierte zunahme an neuronalen stammzellen und dessen therapeutische anwendung
EP1430113A2 (de) * 2001-09-18 2004-06-23 Stem Cell Therapeutics Inc. Wirkung von wachstumshormon und igf-1 auf neurale stammzellen und therapeutische anwendung
EP2095823A1 (de) 2002-07-30 2009-09-02 Stem Cell Therapeutics Inc. Oligodendrozytenherstellung aus multipotenten neuralen Stammzellen
AU2003250705A1 (en) * 2002-07-31 2004-02-16 Stem Cell Therapeutics Inc. Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (pacap)
JP4477506B2 (ja) * 2002-11-27 2010-06-09 Ｉｌｓ株式会社 ペプチド及びこれを含む医薬組成物
JP4990634B2 (ja) * 2004-02-13 2012-08-01 ステム セル セラピューティクス コーポレイション 神経幹細胞の増殖および神経発生のための黄体化ホルモン（ＬＨ）、および絨毛性ゴナドトロピン（ｈＣＧ）の使用
AU2005291810B2 (en) 2004-10-07 2011-12-08 Stem Cell Therapeutics Corp. Stimulation of proliferation of pluripotential stem cells through administration of pregnancy associated compounds
US7007328B1 (en) * 2004-11-05 2006-03-07 Terry Bailey System and apparatus for upper body support of a recumbent person
AU2006297041A1 (en) 2005-09-27 2007-04-05 Stem Cell Therapeutics Corp. Oligodendrocyte precursor cell proliferation regulated by prolactin
EP2004211A4 (de) * 2006-03-17 2010-07-07 Stem Cell Therapeutics Corp Dosierschemata für lh oder hcg und epo zur behandlung von neurologischen erkrankungen
JP5993744B2 (ja) 2009-12-29 2016-09-14 カッパーアールエヌエー，インコーポレイテッド 核呼吸因子１（ｎｒｆ１）に対する天然アンチセンス転写物の阻害による核呼吸因子１関連疾患の治療
CN111344300B (zh) * 2017-11-14 2024-08-30 千寿制药株式会社 Pacap的稳定化肽

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562175A (en) * 1984-02-03 1985-12-31 Ding Chang Synthetic peptides
US4605641A (en) * 1984-10-09 1986-08-12 Hoffmann-La Roche Inc. Synthetic vasoactive intestinal peptide analogs
JPS62246595A (ja) * 1986-04-17 1987-10-27 Eisai Co Ltd 気菅支拡張作用・降圧作用ペプタイド
US5128242A (en) * 1989-06-19 1992-07-07 The Administrators Of The Tulane Educational Fund Hypothalamic polypeptides with adenylate cyclase stimulating activity
US5198542A (en) * 1989-06-20 1993-03-30 Takeda Chemical Industries, Inc. Dna encoding a pitvitary adenylate cyclase activating protein and use thereof
EP0768090A3 (de) * 1990-07-18 1997-06-18 Takeda Chemical Industries Ltd Polypeptide mit c-AMP produzierender Aktivität zur Vorbeugung des neuronalen Zelltodes

Also Published As

Publication number Publication date
US5623050A (en) 1997-04-22
DE69228277T2 (de) 1999-07-08
DE69228277D1 (de) 1999-03-11
EP0529487A3 (en) 1994-06-22
EP0529487B1 (de) 1999-01-27
EP0529487A2 (de) 1993-03-03
US5801147A (en) 1998-09-01
CA2076593C (en) 2002-06-04
CA2076593A1 (en) 1993-02-23

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties