ATE168681T1 - 3-phenylureido-1,5-benzodiazepin-dione verwendbar als gastrin- oder cck antagonisten - Google Patents

3-phenylureido-1,5-benzodiazepin-dione verwendbar als gastrin- oder cck antagonisten

Info

Publication number
ATE168681T1
ATE168681T1 AT94915089T AT94915089T ATE168681T1 AT E168681 T1 ATE168681 T1 AT E168681T1 AT 94915089 T AT94915089 T AT 94915089T AT 94915089 T AT94915089 T AT 94915089T AT E168681 T1 ATE168681 T1 AT E168681T1
Authority
AT
Austria
Prior art keywords
phenylureido
gastrin
benzodiazepine
antagonists
pct
Prior art date
Application number
AT94915089T
Other languages
English (en)
Inventor
Harry Finch
David Gordon Trist
Aldo Feriani
Giorgio Tarzia
Pritom Shah
Original Assignee
Glaxo Wellcome Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Wellcome Spa filed Critical Glaxo Wellcome Spa
Application granted granted Critical
Publication of ATE168681T1 publication Critical patent/ATE168681T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
AT94915089T 1993-04-23 1994-04-22 3-phenylureido-1,5-benzodiazepin-dione verwendbar als gastrin- oder cck antagonisten ATE168681T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939308431A GB9308431D0 (en) 1993-04-23 1993-04-23 Chemical compounds

Publications (1)

Publication Number Publication Date
ATE168681T1 true ATE168681T1 (de) 1998-08-15

Family

ID=10734357

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94915089T ATE168681T1 (de) 1993-04-23 1994-04-22 3-phenylureido-1,5-benzodiazepin-dione verwendbar als gastrin- oder cck antagonisten

Country Status (8)

Country Link
US (1) US5641775A (de)
EP (1) EP0698014B1 (de)
JP (1) JPH08509236A (de)
AT (1) ATE168681T1 (de)
AU (1) AU6646894A (de)
DE (1) DE69411909D1 (de)
GB (1) GB9308431D0 (de)
WO (1) WO1994025444A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9308431D0 (en) * 1993-04-23 1993-06-09 Glaxo Spa Chemical compounds
US5739129A (en) * 1994-04-14 1998-04-14 Glaxo Wellcome Inc. CCK or gastrin modulating 5-heterocyclic-1, 5 benzodiazepines
PE27497A1 (es) * 1994-04-15 1997-08-07 Glaxo Inc Derivados de 1,5 benzodiazepina
AU721081B2 (en) * 1996-12-10 2000-06-22 Zeria Pharmaceutical Co., Ltd. 1,5-benzodiazepine derivatives
JP2000026434A (ja) 1998-06-05 2000-01-25 Zeria Pharmaceut Co Ltd 新規１，５−ベンゾジアゼピン誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2641280B1 (fr) * 1988-12-29 1994-01-21 Roussel Uclaf Nouveaux derives de la 2,4-dioxo 2,3,4,5-tetrahydro 1h-1,5-benzodiazepine, leur procede de preparation et leur application comme medicaments
IL101514A (en) * 1991-04-10 1996-01-31 Merck & Co Inc History of benzodiazepines and anticoagulants containing cholecystokinin containing them
WO1993008175A1 (en) * 1991-10-24 1993-04-29 Glaxo Group Limited Benzodiazepine derivatives as antagonists of gastrin and/or cholecystokinin
GEP20001968B (en) * 1992-01-21 2000-03-05 Glaxo Spa Arilthio Compounds as Antibacterial and Antiviral Agents
GB9308431D0 (en) * 1993-04-23 1993-06-09 Glaxo Spa Chemical compounds

Also Published As

Publication number Publication date
AU6646894A (en) 1994-11-21
US5641775A (en) 1997-06-24
GB9308431D0 (en) 1993-06-09
JPH08509236A (ja) 1996-10-01
DE69411909D1 (de) 1998-08-27
WO1994025444A1 (en) 1994-11-10
EP0698014B1 (de) 1998-07-22
EP0698014A1 (de) 1996-02-28

Similar Documents

Publication Publication Date Title
SG55184A1 (en) New imidazopyridines
DK0712408T3 (da) Tropyl-7-azaindol-3-ylcarboxyamider som antihostemiddel
IL115903A0 (en) Use of dioxomorpholines for combating endoparasites new dioxomorpholines and processes for their preparation
FI954579A (fi) Uusia pednisolonijohdannaisia
GR3033528T3 (en) Novel piperidine derivatives with paf antagonist activity
FI973221A (fi) 1-aryyli-2-asyyliammo-etaaniyhdisteitä ja niiden käyttö neurokiniiniantagonisteina, erityisesti neurokiniini 1 antagonisteina
DK0711283T3 (da) Tetrahydro-1H-benzazepinoner og hexahydroazepinoner som selektive cholecystokinin-B-receptorantagonister
ES2115053T3 (es) Derivados indolicos inhibidores de la 5alfa-reductasa de esteroides.
ATE168681T1 (de) 3-phenylureido-1,5-benzodiazepin-dione verwendbar als gastrin- oder cck antagonisten
NO953660D0 (no) Antrakinoner som markeringsmidler for mineraloljer
GR3027609T3 (en) Carbamate derivatives and their use in medicine.
DE69332019T2 (de) 4-oxo-und 4h-imidazo(5,1-c)(1,4)benzoxazine nützlich als benzodiazepinrezeptor-bindemittel.
ES2087567T3 (es) Derivados antibioticos de 7'-amino-naftazarina.
ES2175424T3 (es) Sal de metansulfonato de una arilpiperazina derivada de triptamina y sus solvatos para uso farmaceutico.
ATE154601T1 (de) 4-amino-2-(hetero)aryl-butanamide verwenbar als 5-ht1a-antagonisten