ATE165524T1 - ACCESS VALVE, ITS USE IN A SEPARATOR AND PROCEDURE - Google Patents

ACCESS VALVE, ITS USE IN A SEPARATOR AND PROCEDURE

Info

Publication number
ATE165524T1
ATE165524T1 AT95932854T AT95932854T ATE165524T1 AT E165524 T1 ATE165524 T1 AT E165524T1 AT 95932854 T AT95932854 T AT 95932854T AT 95932854 T AT95932854 T AT 95932854T AT E165524 T1 ATE165524 T1 AT E165524T1
Authority
AT
Austria
Prior art keywords
probe
valve
column
conduit
conduits
Prior art date
Application number
AT95932854T
Other languages
German (de)
Inventor
John Davis
Martin John Hofmann
Original Assignee
Euroflow Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10762247&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE165524(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Euroflow Uk Ltd filed Critical Euroflow Uk Ltd
Application granted granted Critical
Publication of ATE165524T1 publication Critical patent/ATE165524T1/en

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K1/00—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces
    • F16K1/32—Details
    • F16K1/34—Cutting-off parts, e.g. valve members, seats
    • F16K1/44—Details of seats or valve members of double-seat valves
    • F16K1/443—Details of seats or valve members of double-seat valves the seats being in series
    • F16K1/446—Details of seats or valve members of double-seat valves the seats being in series with additional cleaning or venting means between the two seats
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • B01D15/206—Packing or coating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/22—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the construction of the column
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/56—Packing methods or coating methods
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/56—Packing methods or coating methods
    • G01N2030/562—Packing methods or coating methods packing
    • G01N2030/565—Packing methods or coating methods packing slurry packing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6017—Fluid distributors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Vehicle Body Suspensions (AREA)
  • Peptides Or Proteins (AREA)
  • Channel Selection Circuits, Automatic Tuning Circuits (AREA)
  • Multiple-Way Valves (AREA)
  • Manipulator (AREA)
  • Check Valves (AREA)
  • Filtering Of Dispersed Particles In Gases (AREA)

Abstract

An access valve suitable for controlling fluid flow into and out of a chromatography column has a central axially movable probe with a head (71) acting as a spool valve in a barrel (6). Axial movement of the probe adjusts the valve between a fully open condition, in which both a first conduit (73) extending through the probe and a second conduit (51) defined around the probe are open to the column interior, a partly open condition in which a second sealing land (76) on the probe closes the second conduit (51), and a fully closed position in which both conduits are closed. The three positions are useful for packing and unpacking chromatography media into and from the column. In the closed condition of the valve, the first and second conduits (73, 51) communicate with one another so that the valve interior can be cleaned while the column is operating.
AT95932854T 1994-10-03 1995-10-03 ACCESS VALVE, ITS USE IN A SEPARATOR AND PROCEDURE ATE165524T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9419888A GB9419888D0 (en) 1994-10-03 1994-10-03 Apparatus and techiques for separation

Publications (1)

Publication Number Publication Date
ATE165524T1 true ATE165524T1 (en) 1998-05-15

Family

ID=10762247

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95932854T ATE165524T1 (en) 1994-10-03 1995-10-03 ACCESS VALVE, ITS USE IN A SEPARATOR AND PROCEDURE

Country Status (11)

Country Link
EP (1) EP0776243B1 (en)
JP (2) JP3486415B2 (en)
AT (1) ATE165524T1 (en)
AU (1) AU690747B2 (en)
CA (1) CA2198035C (en)
DE (2) DE69502288T2 (en)
DK (1) DK0776243T3 (en)
ES (1) ES2101667T3 (en)
GB (1) GB9419888D0 (en)
WO (1) WO1996010451A1 (en)
ZA (1) ZA958290B (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5902485A (en) 1994-10-03 1999-05-11 Amersham Pharmacia Biotech Ab Access valve devices, their use in separation apparatus and corresponding methods
GB2325418B (en) * 1997-05-23 2001-04-11 Millipore Corp Chromatographic column and valve
US6117317A (en) * 1997-05-23 2000-09-12 Millipore Investment Holdings Limited Chromatographic column and valve with movable valve sleeve
SE9702169D0 (en) 1997-06-06 1997-06-06 Pharmacia Biotech Ab Chromatography column end arrangements
WO1999022234A1 (en) * 1997-10-27 1999-05-06 Millipore Corporation Chromatographic column and valve
US6136197A (en) * 1998-05-27 2000-10-24 Battelle Memorial Institute Systems for column-based separations, methods of forming packed columns, and methods of purifying sample components
GB9812344D0 (en) * 1998-06-08 1998-08-05 Euroflow Uk Ltd Methods and apparatus for packing chromatography columns
GB2344543B (en) 1998-12-10 2002-11-27 Millipore Corp Chromatography column system and method of packing a chromatography system
DE10029142B4 (en) * 2000-06-14 2004-08-05 InfraServ GmbH & Co. Höchst KG Method for unpacking chromatography columns and device suitable therefor
US6966991B2 (en) * 2000-07-28 2005-11-22 Pall Corporation Methods and apparatus for packing chromatography columns and chromatography column
DE10054781B4 (en) * 2000-11-04 2004-01-29 InfraServ GmbH & Co. Höchst KG Container with a closable opening
GB0328674D0 (en) 2003-12-10 2004-01-14 Euroflow Uk Ltd Chromatography columns and their operation
GB0415394D0 (en) * 2004-07-08 2004-08-11 Euroflow Uk Ltd Chromatography columns and their operation
EP1775001A1 (en) * 2005-10-13 2007-04-18 Xendo Holding B.V. Device for chromatographic separations
GB0614315D0 (en) 2006-07-19 2006-08-30 Ge Healthcare Bio Sciences Ab Chromatography columns, systems and methods
US9597611B2 (en) 2007-03-09 2017-03-21 Ge Healthcare Bioprocess R&D Ab Packing system and method for chromatography columns
US9597610B2 (en) 2007-03-09 2017-03-21 Ge Healthcare Bioprocess R&D Ab Packing system and method for chromatography columns
GB0704603D0 (en) * 2007-03-09 2007-04-18 Ge Healthcare Bio Sciences Ab Packing system and method for chromatography columns
JP5227253B2 (en) * 2009-05-07 2013-07-03 オルガノ株式会社 Separation column for liquid chromatography
WO2010132011A1 (en) * 2009-05-15 2010-11-18 Ge Healthcare Bio-Sciences Ab Filter holder in a chromatography column
US9289699B2 (en) 2009-07-30 2016-03-22 Hoffmann-La Roche Inc. Moveable chromatography column separator
SE1000230A1 (en) * 2010-03-12 2011-09-06 Ge Healthcare Bio Sciences Ab Chromatography column fixture
JP5736732B2 (en) * 2010-11-02 2015-06-17 栗田工業株式会社 Chromatography column and its movable stopper
CN103339502B (en) 2011-02-02 2016-02-17 霍夫曼-拉罗奇有限公司 Column support
WO2013191631A1 (en) * 2012-06-21 2013-12-27 Ge Healthcare Bio-Sciences Ab Chromatography column nozzle
EP3224613B1 (en) 2014-11-28 2019-07-31 GE Healthcare Bio-Sciences AB Method of assessing the cleanness of a bed support in a column
GB201504695D0 (en) * 2015-03-19 2015-05-06 Biotechflow Ltd Chromatography columns and processes
CN105435488B (en) * 2015-12-22 2018-01-23 荣捷生物工程（苏州）有限公司 Unload column valve and containing automatic chromatographic apparatus and the device usage for unloading column valve
WO2024127801A1 (en) * 2022-12-13 2024-06-20 Jsr株式会社 Chromatography apparatus, slurry filling method, and chromatography system

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE356682B (en) * 1969-06-26 1973-06-04 Tetra Pak Int
SE437710B (en) * 1977-01-29 1985-03-11 Tuchenhagen Otto Gmbh PIPE CONNECTORS WITH LEAK CONTROL AND CLEANABLE LECK CHAMBER AND EXPORTED AS DOUBLE-SET COUPLING FOR PIPE PIPES
DE3107429C2 (en) * 1981-02-27 1986-11-20 Otto Tuchenhagen GmbH & Co KG, 2059 Büchen Cleanable sampling valve
US5213683A (en) * 1991-08-08 1993-05-25 Chromaflow, Inc. Apparatus for charging and discharging of chromatography column bed

Also Published As

Publication number Publication date
AU690747B2 (en) 1998-04-30
JP3721180B2 (en) 2005-11-30
JP2004045416A (en) 2004-02-12
EP0776243A1 (en) 1997-06-04
DE69502288D1 (en) 1998-06-04
DE776243T1 (en) 1997-11-20
CA2198035C (en) 2000-08-01
ES2101667T1 (en) 1997-07-16
GB9419888D0 (en) 1994-11-16
JP3486415B2 (en) 2004-01-13
DK0776243T3 (en) 1999-01-18
DE69502288T2 (en) 1998-10-08
ES2101667T3 (en) 1998-09-01
WO1996010451A1 (en) 1996-04-11
EP0776243B1 (en) 1998-04-29
AU3573895A (en) 1996-04-26
ZA958290B (en) 1996-04-24
JPH10506470A (en) 1998-06-23
CA2198035A1 (en) 1996-04-11

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee
UEP Publication of translation of european patent specification